PROSITE entry PS52014
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General information about the entry
| Entry name [info] | SAMD1_WH |
| Accession [info] | PS52014 |
| Entry type [info] | MATRIX |
| Date [info] |
03-MAY-2023 CREATED;
03-MAY-2023 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC52014 |
| Associated ProRule [info] | PRU01358 |
Name and characterization of the entry
| Description [info] | SAMD1-like winged helix (WH) domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=77; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=72; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.1320529; R2=0.0085043; TEXT='-LogE'; /CUT_OFF: LEVEL=0; SCORE=1220; N_SCORE=12.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=514; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-23; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='M'; M=-38,-13,-33,-26,-74,-35,-75, 7, 18,-23, 31,-43,-35,-66, 12, 18, -3, 18,-36,-73; /M: SY='R'; M=-46,-21, 10,-24,-76,-38, 6,-77, 0,-38, 7, -3, 5,-14, 58, 1,-24,-37,-84, 6; /M: SY='R'; M=-12,-52, -7, 2,-82,-29,-64,-56,-22,-50,-13,-13,-25, 0, 76,-12,-15,-34,-86,-73; /M: SY='M'; M= 2,-79,-26, 8,-42,-35, 17, 0,-11,-20, 48,-21, 5, 38, -3, 0,-23,-19,-80, -9; /M: SY='S'; M= 30, 15, -6,-42,-33,-17,-10,-69,-25,-29,-67,-10, 35,-63,-46, 37, 26,-21,-86,-72; /M: SY='D'; M=-42, 33, 71, -5,-32,-34,-18,-37,-34,-34,-29, 16, -5,-37,-40, 24, -7,-41,-93,-71; /M: SY='P'; M=-27,-82, -1, 26,-81,-43,-24,-42,-42,-50, 13, 14, 81,-27,-45, 8, 6,-40,-86,-76; /M: SY='Q'; M=-30,-78, -8, 28,-12,-59, -7, 3, 20,-22,-61,-16,-36, 41,-14,-23, 32, 2,-82,-65; /M: SY='W'; M=-27,-18,-48,-51,-21,-78, 19, 19,-20,-17,-31, -2,-25,-20,-10,-65, 22, 20, 92, 34; /M: SY='V'; M=-11,-26,-28,-51,-18,-78,-13, -4, 9, -2,-24,-66,-23, 20, 0,-26, 22, 44,-10, -5; /M: SY='Q'; M=-37,-26, 13, 34,-81,-25, 29,-46, 29,-33,-25,-20,-33, 61, 11, -1,-33,-53,-83,-67; /M: SY='W'; M=-47, 10,-54,-13,-20,-77, 33,-44, 14,-18,-11,-24,-47, 43, 3,-50,-46,-20,116, 13; /M: SY='I'; M=-22,-34,-44,-82,-25,-88,-82, 71,-80, 38, 1,-81,-81,-77,-82,-75,-62, 32,-79,-60; /M: SY='W'; M=-48,-83,-87,-39,-32,-82,-35, 21,-39, 45, 0,-49,-82,-33,-33,-78,-72,-29,129,-13; /M: SY='D'; M= -5,-79, 68, 47,-32,-25,-60,-47,-37,-65,-14, 4,-13, -2,-15, 6,-13,-60,-88,-71; /M: SY='A'; M= 82, -7,-70,-40,-76,-33,-73,-34,-66,-67,-18,-64,-70,-63,-71, 3, -1, -9,-81,-73; /M: SY='I'; M=-66,-79,-87,-84,-31,-91,-85, 96,-80,-22,-10,-78,-77,-35,-82,-48,-60, 20,-76,-24; /M: SY='R'; M= -3,-13, 28, 31,-78,-12, 22,-62, 18,-54,-68, 6,-70,-10, 43, 2,-17,-25, 2,-67; /M: SY='K'; M=-25, 11,-21, -8,-13,-57, 23,-18, 55,-39,-26, -8,-71, 7, -1, 9, 7, 0,-77, -2; /M: SY='I'; M= -2, 4,-83,-79,-30,-82,-79, 74,-77, 27, -2,-43,-37,-74,-79,-16,-41, 18,-78,-61; /M: SY='R'; M=-65,-14,-33,-33,-75,-74,-59,-31, 62,-46, -3, -4,-72, -6, 76,-12,-61,-20,-79,-66; /M: SY='H'; M= 1,-76,-21, -9,-32, 3, 60,-69, 6,-40,-22, 0,-72, 14, 21, 29,-36,-12,-75, 29; /M: SY='Q'; M=-63,-83,-37,-19,-82,-48, 35,-76,-26,-39, -1,-13,-71,102, 50, -5,-63,-76,-78,-62; /M: SY='K'; M=-66,-80,-58,-47,-80,-48, 14,-82, 88,-79,-67, -2,-69,-20, 59,-59,-38,-78,-77,-66; /I: I=-45; MD=-115; /M: SY='Q'; M= 10,-34,-61,-44,-83,-47,-55,-49,-23,-38,-60,-23,-38,110, 2,-41,-28,-38,-76,-36; D=-45; /I: I=-45; MI=-115; IM=-115; DM=-115; /M: SY='R'; M=-14, 27,-69,-60,-40,-55,-62, 16,-19,-38, -6,-61,-18, 13, 79, 1, -9,-13,-78,-31; /M: SY='P'; M= 36, 2,-70,-60,-81,-65,-72,-68,-65,-60,-68,-70,103,-66,-42, -8,-24,-17,-82,-79; /M: SY='N'; M=-49, 1, 61,-52,-79,-49,-56,-54,-56,-79,-73, 73, -6,-56,-43, 33, 43,-72,-95,-72; /M: SY='L'; M= 12,-73,-35, 20, -3,-43,-68, 16,-24, 37, 36,-69,-36, 1,-68, -8,-60, 10, -4,-59; /M: SY='E'; M=-18,-79, 52, 72,-31,-41,-59,-33, -9,-59,-40,-29,-38, 17,-57,-10, 9,-71,-12,-69; /M: SY='R'; M=-67,-82,-63,-55,-75,-39,-30,-78, 20,-44,-65, 4,-76,-45,101,-32,-38,-33,-78,-31; /M: SY='I'; M=-66,-78,-87,-84,-30,-63,-84, 92,-80, 11, 16,-79,-39,-77,-82,-75,-61, 19,-76,-58; /M: SY='C'; M= -5, 78,-72,-69, -1,-56,-19, 28,-18,-14,-56,-63,-75, -1,-49, 42, 3, 11,-80,-28; /M: SY='R'; M= 0,-77,-57,-23,-74,-27, 40,-76, 40,-46,-22, 43,-42, 8, 49, 10,-33,-53, 17,-22; /M: SY='Y'; M= 23,-39,-40,-67, 24,-58, 29, -1,-25,-26, 20,-36, -7,-63, 3,-36, 2, 1, 11, 69; /M: SY='M'; M=-13, 19,-81,-75,-28,-64,-69, 31,-72, 43, 84,-37,-77,-68,-73,-46,-34, 40,-76,-56; /I: I=-21; MD=-53; /M: SY='R'; M=-18, -5,-62, -9,-30,-42, 7,-53, 16, 4, 10, 7,-73, 38, 52, 18,-36,-29,-75, -1; D=-21; /I: I=-21; MI=0; MD=-53; IM=0; DM=-53; /M: SY='R'; M=-33,-78,-39,-47,-76,-49, -5,-51, 60,-32,-36, -2,-36, 50, 74,-22,-33,-71,-75,-63; /M: SY='H'; M=-35, 5, -8, 21,-32,-56, 48,-53, 28,-50,-31, 36,-36, 21, 43, 3,-22, 3,-79,-13; /M: SY='H'; M=-48,-12,-23,-29, 14,-72, 99,-34,-43,-12,-52, -5,-45, -7,-25,-13,-32,-49,-58, 84; /M: SY='G'; M=-27,-74, 26,-36,-32, 51, 3,-53, 6,-49,-67, 32, -5, 24, 0, 28,-16,-53,-79,-67; /M: SY='M'; M=-29, 24,-78,-73, 28,-79,-67, 40,-51, 17, 47,-37,-12,-11,-29,-66, -8, 34, 8, 35; /M: SY='T'; M=-31,-19, 27, -1,-50, -1, 38,-50, 8,-53,-65, 20, 26,-28,-32, 41, 43,-45,-83,-43; /M: SY='P'; M= 1,-75, -8, 41,-36,-13,-38,-67, -1,-44,-64, -4, 53, 9, 2, 20, 3, -5, -3,-34; /M: SY='D'; M= 4,-35, 41, 36,-43,-17, -1,-72, 29,-44,-65, 22,-66, 33, -2, 12,-10,-24,-18,-65; /M: SY='E'; M=-31,-74, 41, 58,-33,-50,-58,-33, -1,-48,-64,-18,-42, 36,-17, -2, 41, -3,-82,-66; /M: SY='V'; M= 3, 40,-72,-32,-58,-52,-76, 49,-37, -9,-47,-34,-71,-68,-72,-38, 50, 52,-82,-63; /M: SY='E'; M= -2,-25,-18, 61,-69,-49,-38, -1, 3, 11,-56, -9,-48, 36, 11,-30, 1,-12,-78,-65; /M: SY='E'; M= 13,-75,-22, 45,-69,-28, 36,-51, 26, 15,-20,-29,-67, 9, 35,-10,-28,-43,-78,-63; /M: SY='Q'; M=-26, 5, 22, -2,-41,-41, 71,-49, -9,-13, -4, 3,-50, 71, -4,-38,-14,-37,-12, 19; /I: I=-23; MI=0; MD=-58; IM=0; DM=-58; /M: SY='L'; M=-65,-70,-84,-77,-25,-86,-71, 24,-78, 81,-15,-82,-41,-72,-76,-76,-61, 15,-72,-54; /M: SY='E'; M=-16,-76, 42, 59,-79,-19, 26,-76, 18,-74,-20, 16,-63, 41,-15, 2, -6,-38,-83,-66; /M: SY='Q'; M=-13,-76, 13, 24, -9,-70, 24,-45, 18, 15,-56, 19,-70, 53, 26,-28,-30,-58, 4, 7; /M: SY='C'; M= 61, 75,-73,-67,-39,-25,-69,-26,-66, 33, 21,-66,-74,-40,-25, -8,-25,-51,-77,-65; /M: SY='V'; M=-33, 5,-76, -4,-55,-55,-30, 25,-50, 9,-43,-73,-76,-70,-73,-30,-32, 83,-83,-61; /M: SY='K'; M= 4,-75, 15, 44,-78,-16, -3,-39, 50,-57,-36, 14,-64, 33, 21, 2,-25,-70,-79,-66; /M: SY='D'; M=-10,-12, 86, 26,-42,-64, 9,-77, 0,-58,-71, 4,-67, 3, 0, 14,-55,-39,-87,-38; /M: SY='G'; M=-29, -8,-27,-20,-80, 81,-20,-84, 10,-62,-71, 23,-68,-25, 17,-15,-62,-79,-77,-73; /M: SY='L'; M=-16,-32,-10,-40,-29,-50,-39, 13, 11, 63,-41,-35,-75, 6,-17, -9,-10,-25,-74,-58; /M: SY='I'; M=-59,-71,-83,-78,-36,-85,-80, 74,-75, 23,-12,-76,-77,-73,-46,-20,-55, 61,-78,-58; /M: SY='L'; M=-27, -3,-70, 3,-10,-78,-39, 36,-38, 37, 13,-29,-19,-17, -2,-30, 10, 32,-75,-31; /M: SY='K'; M=-28,-36,-33, 20,-43,-46,-58,-33, 68,-34,-32,-31,-18, 0, 43, 3,-12,-10,-74,-16; /M: SY='V'; M=-25,-21,-20,-30,-54,-50,-69, 24,-12, 1,-47,-20,-74,-65,-14, -6, 15, 65,-75, 27; /I: I=-33; MI=0; MD=-84; IM=0; DM=-84; /M: SY='K'; M=-49,-73, -8, 27, 18,-11, 8, 1, 31,-13, 12, -2,-15,-33,-40, 16, 16,-21, 13, 9; /M: SY='Y'; M= -5,-73,-34,-26, 11, -3, 5,-31, 29,-52,-61, 42,-20,-29, 20, 6, 15,-34, 6, 48; /M: SY='K'; M=-21,-40, 11,-10,-47,-24,-25, 0, 67,-27,-22, 25,-13, 8,-22,-30,-35, 19,-78,-64; /M: SY='G'; M= -4,-75, -6,-11,-78, 88,-29,-81,-53,-80,-71,-12,-21,-62,-32,-24,-42,-36,-74,-17; /M: SY='C'; M= -2, 32,-11, -6, -6,-29, 2,-44, 6,-11, 2, 29,-34, 30,-27, 23, 23, 7,-78,-26; /M: SY='K'; M= -8, 4,-12,-27,-31,-54, 8, 3, 52,-27,-19, 4, -9,-27,-10,-30, 20, 22, 9, 12; /M: SY='S'; M=-35, 6,-60,-62,-74, 47, -2,-35,-22,-73,-66,-31,-34,-56, -2, 72, 24,-13,-81,-68; /M: SY='Y'; M=-25,-26,-38,-67,-12,-70,-45,-30,-31,-19,-52,-34,-77,-29,-62, 37,-26,-48,-40,114; /M: SY='R'; M=-20,-78,-60,-19,-74,-72,-16,-39, 63,-50,-12,-23,-26,-14, 83,-26,-43,-33,-76,-63; /M: SY='D'; M= 2,-22, 51,-25,-67,-48,-61, 18, -5, -3,-17, 49, -6,-13,-38,-20, -4, 17,-84,-66; /M: SY='P'; M= 34,-20,-41,-45,-76, 51,-70,-67,-48,-26,-64,-39, 76,-64,-72,-38, 7,-11,-78,-74; /M: SY='S'; M= 18,-10, 9, 10,-69, -9,-62, -1, 3,-21, 4, 23,-15, 6,-35, 25, 2, 17,-81,-66; /M: SY='E'; M= -6,-74,-12, 45, 10, -8, 16,-69, 26,-44,-19, -9, -5, 13, -7, 29, -1,-23, 1,-60; /M: SY='W'; M= -9,-36, 6, -2,-46,-69, -9,-32, 2,-21, 29,-31, -9, 65, -9, 9, 2, 4, 72,-29; /I: E1=0; IE=-380; DE=-380;» more |
Numerical results [info]
| Total number of hits | 11 in 11 different sequences |
| Number of true positive hits | 11 in 11 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | SAMD1-like winged helix (WH) |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
11 sequences
KAT6A_HUMAN (Q92794), KAT6A_MOUSE (Q8BZ21), KAT6A_RAT (Q5TKR9), KAT6B_HUMAN (Q8WYB5), KAT6B_MACFA (Q8WML3), KAT6B_MOUSE (Q8BRB7), SAMD1_HUMAN (Q6SPF0), SAMD1_MOUSE (D3YXK1), SAMD1_RABIT (Q6SPE9), ZMY11_HUMAN (Q15326), ZMY11_MOUSE (Q8R5C8)» more
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| PDB [Detailed view] |
3 PDB
6LUI; 7Y43; 8H7A |