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PROSITE entry PS60004


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General information about the entry

Entry name [info] OMEGA_CONOTOXIN
Accession [info] PS60004
Entry type [info] PATTERN
Date [info] 01-OCT-2004 CREATED;
01-OCT-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC60004

Name and characterization of the entry

Description [info] Omega-conotoxin family signature.
Pattern [info] 
C-[SREYKLIMQVN]-x(2)-[DGWET]-x-[FYSPKV]-C-[GNDSRHTP]-x(1,5)-[NPGSMTAHF]-
[GWPNIYRSKLQ]-x-C-C-[STRHGD]-x(0,2)-[NFLWSRYIT]-C-x(0,3)-[VFGAITSNRKL]-
[FLIKRNGH]-[VWIARKF]-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_04 which contains 571'864 sequence entries.


Total number of hits 81 in 81 different sequences
Number of true positive hits 68 in 68 different sequences
Number of 'unknown' hits 0
Number of false positive hits 13 in 13 different sequences
Number of false negative sequences 3
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 83.95 %
Recall (true positives / (true positives + false negatives)) 95.77 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 1
Site [info] disulfide at position 7
Site [info] disulfide at position 13
Site [info] disulfide at position 14
Site [info] disulfide at position 18
Site [info] disulfide at position 23
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 68 sequences 

I166_CONTE  (P0DPM4), M7E_CONCN   (P0DKQ3), M7F_CONCN   (P0DKQ4), 

M7G_CONCN   (P0DKQ5), M7J_CONCN   (P0DKQ6), NEMA1_LINLO (P0DM24), 
NEMA2_LINLO (P0DM25), O1618_CONAE (Q9BP78), O161A_CONPL (Q9XYZ0), 
O161_CONST  (Q9XZL4), O162A_CONPL (Q9XYZ1), O162_CONAA  (A0A2L2P6T9), 
O162_CONAE  (Q9BH84), O162_CONIM  (Q5K0B9), O162_CONST  (Q5K0D8), 
O163_CONAA  (A0A3G3C7S6), O163_CONAE  (Q9BP99), O163_CONIM  (Q5K0C0), 
O163_CONTE  (Q9XZL0), O164_CONAH  (P0C8V8), O164_CONST  (Q9XZK3), 
O164_CONTE  (Q9XZL1), O164_CONVC  (P69761), O165_CONAA  (A0A3G3C7U7), 
O165_CONAH  (P0C8V9), O165_CONST  (Q9XZK4), O165_CONTE  (Q9XZL2), 
O1661_CONTE (Q3YEF3), O166_CONST  (P0C831), O167_CONMR  (Q3YED6), 
O168_CONBU  (P0CY66), O168_CONVE  (Q9BPA5), O16A2_CONST (Q9XZL5), 
O16A_CONCT  (P58917), O16A_CONFU  (P0DW83), O16A_CONGE  (P01522), 
O16A_CONMB  (A0A384E129), O16A_CONPE  (P56712), O16A_CONRA  (P58914), 
O16A_CONST  (P28880), O16A_CONTU  (P58915), O16B_CONCT  (P58918), 
O16B_CONPB  (P0DMA2), O16B_CONPE  (P56713), O16B_CONST  (P28881), 
O16C_CONCT  (P58919), O16C_CONST  (Q5K0D6), O16D_CONCT  (P58920), 
O16E_CONCT  (Q9N633), O16F_CONCT  (P0DQD4), O16F_CONST  (Q5K0D5), 
O16K_CONTE  (Q9U654), O16L6_CONST (Q5K0D3), O16L_CONTE  (Q9U645), 
O16M_CONTE  (Q9U648), O16O2_CONTE (Q9XZK9), O16O3_CONST (Q9XZK2), 
O16O6_CONTE (Q9XZL3), O17A_CONMA  (P05484), O17B_CONMA  (P05485), 
O17C_CONMA  (P37300), O17D_CONMA  (Q26350), O17H_CONCN  (P58916), 
O17_CONTE   (P56714), O194_CONTE  (Q9U647), O19_CONST   (Q5K0D2), 
O1X1_CONTE  (Q9XZK8), U7AB_CONGE  (P05483)
» more

UniProtKB/Swiss-Prot
False negative sequences		 3 sequences 

O161_CONTE  (Q9U651), O162_CONTE  (Q9U650), O167_CONST  (P0C832)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			13 sequences
			


			
NEMA1_LINLC (P0DQS1), NEMA1_LINRU (P0DQS2), NEMA2_LINRU (P0DQS3), 

			
NEMA4_LINSA (P0DQS6), NEMA8_RISOC (P0DQT0), O163_CONAH  (P0C8V7), 
O16A_CONCN  (P69750), O16A_CONMA  (P69753), O16A_CONSE  (P69757), 
O16B_CONMA  (P69754), O16C_CONMA  (P69755), O16D_CONMA  (P69756), 
O16E_CONST  (Q9XZK5)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			22 PDB
			


			1CNN; 1DW4; 1DW5; 1F3K; 1FEO; 1FYG; 1MVI; 1MVJ; 1OMC; 1OMG; 1OMN; 1TR6; 
			
				1TT3; 1TTK; 1TTL; 2CCO; 5ZNU; 6CEG; 6ENA; 7MIX; 7VFU; 8X91
			
			

			» more