PROSITE entry PS60014
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General information about the entry
Entry name [info] | ALPHA_CONOTOXIN |
Accession [info] | PS60014 |
Entry type [info] | PATTERN |
Date [info] |
01-MAR-2005 CREATED;
01-OCT-2005 DATA UPDATE; 03-MAY-2023 INFO UPDATE. |
PROSITE Doc. [info] | PDOC60004 |
Name and characterization of the entry
Description [info] | Alpha-conotoxin family signature. |
Pattern [info] |
C-C-[SHYN]-x(0,1)-[PRG]-[RPATV]-C-[ARMFTNHG]-x(0,4)-[QWHDGENLFYVP]- [RIVYLGSDW]-C. |
Numerical results [info]
Total number of hits | 72 in 72 different sequences |
Number of true positive hits | 67 in 67 different sequences |
Number of 'unknown' hits | 1 |
Number of false positive hits | 4 in 4 different sequences |
Number of false negative sequences | 48 |
Number of 'partial' sequences | 0 |
Precision (true positives / (true positives + false positives)) | 94.37 % |
Recall (true positives / (true positives + false negatives)) | 58.26 % |
Comments [info]
Taxonomic range [info] | Eukaryotes |
Maximum number of repetitions [info] | 1 |
Site [info] | disulfide at position 1 |
Site [info] | disulfide at position 2 |
Site [info] | disulfide at position 7 |
Site [info] | disulfide at position 12 |
Version [info] | 2 |
Cross-references [info]
UniProtKB/Swiss-Prot True positive sequences |
67 sequences
CA11B_CONAH (P0CAQ5 ), CA11_CONAJ (P0CB07 ), CA11_CONSE (P0C8V1 ), CA11_CONTE (Q9XZK6 ), CA12A_CONIM (Q9U619 ), CA12A_CONRE (P85013 ), CA12_CONAA (A0A3G3C7S9), CA12_CONAJ (P0CB08 ), CA12_CONGE (P01520 ), CA12_CONIM (Q8I6R5 ), CA12_CONMA (P56636 ), CA12_CONPE (P0DM23 ), CA12_CONVC (E2DIH5 ), CA13_CONBN (P0C1Y2 ), CA13_CONMR (A0SE59 ), CA14_CONLI (S4UJV1 ), CA14_CONMN (P0C8U5 ), CA15_CONAA (A0A3G3C7S0), CA16_CONAA (A0A3G3C7U1), CA16_CONEB (F2XFS9 ), CA16_CONQU (A1X8D1 ), CA189_CONAJ (P0CB12 ), CA1AB_CONAN (P0C1V7 ), CA1AB_CONSP (P85886 ), CA1A_CONAE (P0C8R2 ), CA1A_CONAL (P56639 ), CA1A_CONBU (P69657 ), CA1A_CONCN (P56973 ), CA1A_CONCT (D4HPD6 ), CA1A_CONEP (P56638 ), CA1A_CONER (P50982 ), CA1A_CONLG (X1WB75 ), CA1A_CONLI (L8BU87 ), CA1A_CONLM (P0DL68 ), CA1A_CONOB (P0DQY0 ), CA1A_CONOM (P0C1R7 ), CA1A_CONPE (P50984 ), CA1A_CONPU (P69658 ), CA1A_CONRE (P0C1D0 ), CA1A_CONST (P28878 ), CA1A_CONVC (P69747 ), CA1A_CONVR (F5C0A0 ), CA1B_CONAL (P56640 ), CA1B_CONOB (P0DQY1 ), CA1B_CONPE (P50985 ), CA1B_CONTE (K4RNX9 ), CA1C_CONAL (P56641 ), CA1C_CONAN (P0C1V8 ), CA1C_CONCN (P0C8U4 ), CA1C_CONGE (Q86RB2 ), CA1D_CONGE (P60274 ), CA1E_CONRE (P85011 ), CA1L_CONCN (P0DKP6 ), CA1Z_CONTE (P0DPL9 ), CA1_CONGE (X5I9Y2 ), CA1_CONIM (P50983 ), CA1_CONMA (P01521 ), CA1_CONST (P15471 ), CA2_CONTE (Q9XZK7 ), CA761_CONIN (P0DUR2 ), CA878_CONIN (P0DUR1 ), CA907_CONIN (P0DUR0 ), CAIA_CONGE (P0DQR7 ), CAIB_CONGE (X5IGW1 ), CAL12_CONPE (Q9BP56 ), CAS2_CONST (P28879 ), O16A_CONVX (Q86RA3 )» more
|
UniProtKB/Swiss-Prot False negative sequences |
48 sequences
CA11A_CONAH (P0CAQ4 ), CA11A_CONQU (Q6PTD7 ), CA11B_CONQU (Q6PPB3 ), CA11C_CONQU (A1X8C6 ), CA11_CONBN (P0CE73 ), CA11_CONBU (P0CY86 ), CA11_CONCB (P0C1V9 ), CA11_CONLE (Q6PTD5 ), CA11_CONLT (Q2I2R8 ), CA11_CONMR (Q6PTD1 ), CA11_CONPL (A0SE60 ), CA11_CONST (P0C1W4 ), CA12_CONBN (P0CE74 ), CA12_CONCB (P0C1W0 ), CA12_CONKI (D4HRK7 ), CA12_CONLE (Q6PTD4 ), CA12_CONLT (Q2I2R7 ), CA12_CONMR (A6M934 ), CA12_CONPL (A1X8D8 ), CA12_CONQU (Q6PTD6 ), CA13_CONLT (Q2I2R6 ), CA14A_CONQU (P0CAQ8 ), CA14B_CONQU (P0CAQ9 ), CA14_CONBR (P0C8U3 ), CA14_CONLE (A1X8B6 ), CA14_CONPL (P0C8U8 ), CA15_CONPL (P0C8U9 ), CA15_CONQU (A1X8D0 ), CA16A_CONLE (P0CAQ6 ), CA16B_CONLE (P0CAQ7 ), CA16_CONPL (P0C8V0 ), CA17_CONLE (A1X8C3 ), CA18_CONLE (A1X8C2 ), CA1A_CONLE (A6M938 ), CA1A_CONMA (P0C1W1 ), CA1A_CONPR (Q1L777 ), CA1A_CONTI (P0CI05 ), CA1B_CONBR (C0HLK1 ), CA1B_CONPU (P0C351 ), CA1B_CONRE (P85009 ), CA1C_CONTE (P86261 ), CA1D_CONRE (P85010 ), CA1F_CONRE (P85012 ), CA1LB_CONRE (C0HJA8 ), CA1_CONQU (A1X8B8 ), CA2_CONQU (A1X8B9 ), CAE1_CONPL (C6ZJQ2 ), CAEA_CONTS (P86362 )» more |
UniProtKB/Swiss-Prot 'Unknown' sequences |
1 sequence
M34_CONMR (P0C1N3 ) |
UniProtKB/Swiss-Prot False positive sequences |
4 sequences
CM314_CONRE (A0A2I6EDN1), O165_CONCL (D6C4L2 ), SJ380_SCHJA (Q5DBT1 ), SJ643_SCHJA (Q5DFA1 )» more |
PDB [Detailed view] |
61 PDB
1A0M; 1AKG; 1B45; 1CNL; 1DG2; 1E76; 1G2G; 1HJE; 1IM1; 1IMI; 1K64; 1M2C; 1MII; 1MTQ; 1MXN; 1MXP; 1NOT; 1PEN; 1QMW; 1UL2; 1XGA; 1XGB; 1XGC; 1ZLC; 2AJW; 2AK0; 2BYP; 2C9T; 2GCZ; 2H8S; 2I28; 2IGU; 2JUR; 2JUS; 2JUT; 2LZ5; 2MD6; 2MDQ; 2NS3; 4EZ1; 4TTL; 5CO5; 5UG3; 5UG5; 5XGL; 6HY7; 6M4X; 6M4Z; 6OTB; 6OVJ; 7EGR; 7N0T; 7N1Z; 7N20; 7N21; 7N22; 7N23; 7N24; 7N25; 7N26; 7N43 » more |