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PROSITE entry PS60021


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General information about the entry

Entry name [info] HWTX_1
Accession [info] PS60021
Entry type [info] PATTERN
Date [info] 01-AUG-2005 CREATED;
01-AUG-2005 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC60021

Name and characterization of the entry

Description [info] Huwentoxin-1 family signature.
Pattern [info] 
C-[KALRVG]-x-{M}-x(1,3)-C-x(4,6)-C-C-x(4,6)-C-x(4)-[ERK]-W-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_04 which contains 571'864 sequence entries.


Total number of hits 129 in 129 different sequences
Number of true positive hits 129 in 129 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 119
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 52.02 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 1
Site [info] disulfide at position 6
Site [info] disulfide at position 8
Site [info] disulfide at position 9
Site [info] disulfide at position 11
Site [info] disulfide at position 15
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 129 sequences 

CCY1A_CHRCN (P0DP93), CCY1B_CHRCN (P0DP94), H12A1_CYRHA (D2Y2C1), 

H12A2_CYRHA (D2Y2H6), H12A3_CYRHA (D2Y2H7), H12A4_CYRHA (D2Y2H8), 
H1A01_CYRHA (D2Y1X6), H1A02_CYRHA (D2Y1X7), H1A03_CYRHA (D2Y1X8), 
H3A01_CYRHA (D2Y1X9), H3A02_CYRHA (D2Y1Y0), H3A03_CYRHA (D2Y1Y1), 
H3A04_CYRHA (D2Y1Y2), H3A05_CYRHA (D2Y1Y3), H3A06_CYRHA (D2Y1Z4), 
H3A07_CYRHA (D2Y1Z7), H3A08_CYRHA (D2Y1Z8), H3A09_CYRHA (D2Y2D1), 
H3A10_CYRHA (D2Y2D2), H3A11_CYRHA (D2Y2D3), H3A12_CYRHA (D2Y2I3), 
H3B01_CYRHA (D2Y1Y4), H3B02_CYRHA (D2Y1Y5), H3B03_CYRHA (D2Y1Z3), 
H3B04_CYRHA (D2Y1Z5), H3B05_CYRHA (D2Y1Z6), H3C01_CYRHA (D2Y1Y6), 
H3D01_CYRHA (D2Y1Y7), H3E01_CYRHA (D2Y1Y8), H3F01_CYRHA (D2Y1Y9), 
H3G01_CYRHA (D2Y1Z0), H3H01_CYRHA (D2Y1Z1), H3I01_CYRHA (D2Y1Z2), 
H3J01_CYRHA (D2Y1Z9), H3K01_CYRHA (D2Y200), H3L01_CYRHA (D2Y201), 
H3M01_CYRHA (D2Y202), H3O01_CYRHA (D2Y2I5), H3P01_CYRHA (D2Y2I6), 
H4A01_CYRHA (D2Y232), H4A02_CYRHA (D2Y233), H4A03_CYRHA (D2Y2D7), 
H4C01_CYRHA (D2Y235), H8A01_CYRHA (D2Y240), H8A02_CYRHA (D2Y241), 
H8A03_CYRHA (D2Y242), H8A04_CYRHA (D2Y243), H8A05_CYRHA (D2Y248), 
H8A06_CYRHA (D2Y249), H8A07_CYRHA (D2Y250), H8A08_CYRHA (D2Y2G3), 
H8A09_CYRHA (D2Y2G4), H8A10_CYRHA (D2Y2G5), H8A11_CYRHA (D2Y2G6), 
H8A12_CYRHA (D2Y2M1), H8A13_CYRHA (D2Y2M4), H8A14_CYRHA (D2Y2M5), 
H8A15_CYRHA (D2Y2M6), H8A16_CYRHA (D2Y2M8), H8A17_CYRHA (D2Y2N0), 
H8A18_CYRHA (D2Y2N1), H8A19_CYRHA (D2Y2N4), H8B01_CYRHA (D2Y244), 
H8D01_CYRHA (D2Y246), H8E01_CYRHA (D2Y247), H8F01_CYRHA (D2Y2G7), 
H8H01_CYRHA (D2Y2G9), H8I01_CYRHA (D2Y2M0), H8K01_CYRHA (D2Y2M3), 
H8L01_CYRHA (D2Y2M9), H8M01_CYRHA (D2Y2N2), H8N01_CYRHA (D2Y2N3), 
H8P01_CYRHA (D2Y2N6), H8Q01_CYRHA (D2Y2N7), H9A01_CYRHA (D2Y236), 
H9A02_CYRHA (D2Y2E8), H9A03_CYRHA (D2Y2E9), H9A04_CYRHA (D2Y2F0), 
H9B01_CYRHA (D2Y237), H9B02_CYRHA (D2Y239), H9B03_CYRHA (D2Y2L7), 
H9C01_CYRHA (D2Y238), H9D01_CYRHA (D2Y2F1), H9E01_CYRHA (D2Y2L5), 
HD1A_CYRDO  (A0A0J9X1W9), HN423_CYRHA (P0CH72), HTX1_CYRLI  (B3EWN2), 
HTX2_CYRLI  (B3EWN3), JZ12A_CHIGU (B1P1C4), JZ12B_CHIGU (B1P1C6), 
JZ13A_CHIGU (B1P1C9), JZ13B_CHIGU (B1P1D0), JZ13C_CHIGU (B1P1C8), 
JZ16B_CHIGU (B1P1D2), JZT10_CHIGU (B1P1C2), JZT18_CHIGU (B1P1D3), 
JZT26_CHIGU (B1P1F2), JZT49_CHIGU (B1P1C7), JZT7A_CHIGU (P0C2X7), 
JZT7B_CHIGU (B1P1A4), NTA_ORPS2   (P0DP95), TX15_GRAPO  (P0DL72), 
TX15_GRARO  (P0DJA9), TX15_PARSR  (P0DL73), TX1_CERDA   (P0DL84), 
TX1_CERMR   (P84507), TX2_CERMR   (P84508), TX3_PARSR   (P84510), 
TX3_SELPU   (P0DM67), TX623_PSACA (P0C246), TXH1_CYRSC  (P56676), 
TXH3_CYRSC  (P61103), TXH4_CYRSC  (P83303), TXH5_CYRSC  (P61104), 
TXHA5_CYRHA (P60975), TXLA1_CYRSC (Q86C51), TXLA3_CYRSC (B3FIS2), 
TXLA4_CYRSC (B3FIS3), TXLA5_CYRSC (B3FIS4), TXLA6_CYRSC (B3FIS5), 
TXLC_CYRSC  (B3FIS0), TXLD_CYRSC  (B3FIS1), TXLF3_CYRHA (P0CH71), 
TXNA1_OMOSC (A0A4V8GZX0), TXP5_BRASM  (P49266), VSTX1_ACAGO (P0DQJ5), 
VSTX1_GRARO (P60980), VSTX3_GRARO (P0C2P5), VSTX3_PARSR (P0DL74)
» more

UniProtKB/Swiss-Prot
False negative sequences		 119 sequences 

DKTX_CYRSC  (P0CH43), H13A1_CYRHA (D2Y2A0), H13A2_CYRHA (D2Y2A1), 

H13A3_CYRHA (D2Y2A2), H13A4_CYRHA (D2Y2B2), H13A5_CYRHA (D2Y2B3), 
H13A6_CYRHA (D2Y2B4), H13A7_CYRHA (D2Y2B5), H13A8_CYRHA (D2Y2H5), 
H13B1_CYRHA (D2Y2A3), H13C1_CYRHA (D2Y2A4), H13E1_CYRHA (D2Y2A5), 
H13F1_CYRHA (D2Y2A6), H13H1_CYRHA (D2Y2A7), H13I1_CYRHA (D2Y2A8), 
H13J1_CYRHA (D2Y2A9), H13K1_CYRHA (D2Y2B0), H13L1_CYRHA (D2Y2B1), 
H13M1_CYRHA (D2Y2H3), H13N1_CYRHA (D2Y2H4), H7A01_CYRHA (D2Y2C3), 
H8C01_CYRHA (D2Y245), H8G01_CYRHA (D2Y2G8), H8J01_CYRHA (D2Y2M2), 
H8O01_CYRHA (D2Y2N5), H9F01_CYRHA (D2Y2L8), HN324_CYRHA (P0CH70), 
JZ11A_CHIGU (P0C247), JZ11B_CHIGU (B1P1E1), JZ11C_CHIGU (B1P1E0), 
JZ11E_CHIGU (B1P1E3), JZ11F_CHIGU (B1P1D9), JZ14A_CHIGU (B1P1C0), 
JZ14B_CHIGU (B1P1C1), JZ20A_CHIGU (B1P1G9), JZ20B_CHIGU (B1P1H0), 
JZ21A_CHIGU (B1P1E6), JZ21B_CHIGU (B1P1E7), JZ21C_CHIGU (B1P1E5), 
JZ31A_CHIGU (B1P1F4), JZ31B_CHIGU (B1P1F3), JZ31C_CHIGU (P0CH56), 
JZ35A_CHIGU (B1P1F9), JZ35B_CHIGU (B1P1F8), JZ38A_CHIGU (B1P1G2), 
JZ38B_CHIGU (B1P1G0), JZ38C_CHIGU (B1P1G3), JZ38D_CHIGU (B1P1G1), 
JZ41A_CHIGU (B1P1G6), JZ41B_CHIGU (B1P1G7), JZ432_CHIGU (P0CH50), 
JZ521_CHIGU (P0CH51), JZ627_CHIGU (P0CH52), JZ67B_CHIGU (B1P1I7), 
JZ710_CHIGU (P0CH54), JZT15_CHIGU (B1P1D4), JZT1A_CHIGU (P83974), 
JZT1B_CHIGU (B1P1B7), JZT1C_CHIGU (B1P1B8), JZT22_CHIGU (B1P1E8), 
JZT23_CHIGU (B1P1E9), JZT24_CHIGU (B1P1F0), JZT25_CHIGU (B1P1F1), 
JZT27_CHIGU (B1P1H2), JZT29_CHIGU (B1P1E4), JZT30_CHIGU (B1P1A0), 
JZT32_CHIGU (B1P1F5), JZT33_CHIGU (B1P1F6), JZT34_CHIGU (B1P1F7), 
JZT36_CHIGU (B1P1D7), JZT37_CHIGU (B1P1D8), JZT39_CHIGU (B1P1G4), 
JZT40_CHIGU (B1P1G5), JZT42_CHIGU (B1P1A2), JZT44_CHIGU (B1P1G8), 
JZT4A_CHIGU (B1P1D5), JZT4B_CHIGU (B1P1D6), JZT60_CHIGU (B1P1H9), 
JZT61_CHIGU (B1P1H1), JZT68_CHIGU (B1P1I8), JZTX2_CHIGU (B1P1B9), 
JZTX3_CHIGU (P62520), MTX4_GRARO  (Q7YT39), NTA_MACGS   (Q75WH5), 
TX1A_HETMC  (P60992), TX1_STRCF   (P60991), TX1_STRGF   (P56855), 
TX1_THEBL   (P83745), TX26A_PHONI (P86418), TX27_PHONI  (P83996), 
TX27_PHORI  (P83892), TX29_PHONI  (P29426), TX2_HETMC   (P60993), 
TX2_THEBL   (P83746), TX32_PHOKE  (P83910), TX3_CERMR   (P84509), 
TX3_THEBL   (P83747), TX482_HYSGI (P56854), TX4_SELPU   (P0DM68), 
TX5A_HETVE  (P61789), TX5B_HETVE  (P61790), TX621_PSACA (P0C244), 
TX622_PSACA (P0C245), TXG1D_CHIGU (P84836), TXG1E_CHIGU (P84835), 
TXG2_CHIGU  (P84837), TXHN1_GRARO (P56852), TXHN2_GRARO (P56853), 
TXHP1_HETVE (P58425), TXHP2_HETVE (P58426), TXHP3_HETVE (P58427), 
TXJ1_HETVE  (P61791), TXLB1_CYRSC (B3FIS6), TXLB2_CYRSC (B3FIS7), 
TXM1A_PTEMU (P0DQZ2), TXPR1_THRPR (P83480), TXT1_CYRSC  (P68426), 
TXU2_HETVE  (P61792), WGRTX_GRARO (P60590)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

HN131_CYRHA (P0CH59)


				
	

	

		PDB
[Detailed view]		
		
			25 PDB
			


			1MB6; 1NIX; 1NIY; 1QK6; 1QK7; 1RYV; 1S6X; 1ZJQ; 2AAP; 2JTB; 2M4X; 2M50; 
			
				2MPQ; 2MQF; 2MXO; 2N1N; 5T3M; 5TLR; 5WE3; 6BR0; 6BTV; 6GFT; 6MK5; 6W6O; 
				7K48
			
			

			» more