PROSITE logo

PROSITE entry PS00059


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00059
Entry name [info] ADH_ZINC
Accession [info] PS00059
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00058

Name and characterization of the entry

Description [info] Zinc-containing alcohol dehydrogenases signature.
Pattern [info] 
G-H-E-x-{EL}-G-{AP}-x(4)-[GA]-x(2)-[IVSAC].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 535 in 535 different sequences
Number of true positive hits 520 in 520 different sequences
Number of 'unknown' hits 0
Number of false positive hits 15 in 15 different sequences
Number of false negative sequences 50
Number of 'partial' sequences 7
Precision (true positives / (true positives + false positives)) 97.20 %
Recall (true positives / (true positives + false negatives)) 91.23 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] zinc at position 2
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 520 sequences 

10HGO_CATRO (Q6V4H0), 8HGO_CATRO  (W8JWV8), ACAR_METS5  (A4YGN2),
» more

UniProtKB/Swiss-Prot
False negative sequences		 50 sequences 

AHNL_LINUS  (P93243), CCR_STRAW   (Q82LU9), CIPB_EMENI  (Q5AUY5),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 7 sequences 

ADH1_ANAPL  (P30350), ADH1_CATRO  (P85440), ADH1_ZEALU  (Q07264),
» more

UniProtKB/Swiss-Prot
False positive sequences		 15 sequences 

ATG2A_HUMAN (Q2TAZ0), ATG2A_MOUSE (Q6P4T0), DYP_AURAJ   (I2DBY1),
» more

PDB
[Detailed view]		 214 PDB

1A71; 1A72; 1ADB; 1ADC; 1ADF; 1ADG; 1AGN; 1AXE; 1AXG; 1BTO; 1BXZ; 1CDO;
» more