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PROSITE entry PS00121


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PURL: https://purl.expasy.org/prosite/signature/PS00121

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General information about the entry

Entry name [info] COLIPASE_1
Accession [info] PS00121
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-1990 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00111

Name and characterization of the entry

Description [info] Colipase signature.
Pattern [info] 
Y-x(2)-Y-Y-x-C-x-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 14 in 14 different sequences
Number of true positive hits 12 in 12 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 4
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 85.71 %
Recall (true positives / (true positives + false negatives)) 75.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] interfacial_binding at position 1
Site [info] interfacial_binding at position 3
Site [info] interfacial_binding at position 4
Site [info] disulfide at position 6
Site [info] disulfide at position 8
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 12 sequences 

COLA_HORSE  (P02704), COLB_HORSE  (P02705), COL_BOVIN   (A0JNQ7), 

COL_CANLF   (P19090), COL_HUMAN   (P04118), COL_ICTTR   (Q91XL7), 
COL_MOUSE   (Q9CQC2), COL_MYOCO   (P42889), COL_PIG (P02703), 
COL_RABIT   (P42890), COL_RAT (P17084), COL_XENTR   (A9JSD6)
» more

UniProtKB/Swiss-Prot
False negative sequences		 4 sequences 

COLL1_HUMAN (A2RUU4), COLL2_HUMAN (Q6UWE3), COLL2_MOUSE (Q3UW21), 

COLL2_RAT   (D3ZVN1)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 2 sequences 

COL_CHICK   (P11148), COL_SQUAC   (P11149)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			2 sequences
			


			
PGA15_CANAL (Q5A1E1), YLOH_SCHPO  (Q9URY3)


				
	

	

		PDB
[Detailed view]		
		
			6 PDB
			


			pdb_00001eth; pdb_00001lpa; pdb_00001lpb; pdb_00001n8s; pdb_00001pcn; pdb_00001pco