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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS00180


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PURL: https://purl.expasy.org/prosite/signature/PS00180

Direct ScanProsite submission
General information about the entry

Entry name [info] GLNA_1
Accession [info] PS00180
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-NOV-1995 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00162

Name and characterization of the entry

Description [info] Glutamine synthetase signature 1.
Pattern [info] 
[FYWL]-D-G-S-S-x(6,8)-[DENQSTAK]-[SA]-[DE]-x(2)-[LIVMFY].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 167 in 167 different sequences
Number of true positive hits 155 in 155 different sequences
Number of 'unknown' hits 0
Number of false positive hits 12 in 12 different sequences
Number of false negative sequences 28
Number of 'partial' sequences 6
Precision (true positives / (true positives + false positives)) 92.81 %
Recall (true positives / (true positives + false negatives)) 84.70 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 155 sequences 

3HAPM_CUPPJ (Q46ZL2), GLN11_ARATH (Q56WN1), GLN11_ORYSJ (P14656), 

GLN12_ARATH (Q8LCE1), GLN12_ORYSJ (P14654), GLN13_ARATH (Q9LVI8), 
GLN13_ORYSJ (Q4W8D0), GLN14_ARATH (Q9FMD9), GLN15_ARATH (Q8GXW5), 
GLN1A_BACCE (P19064), GLN1A_BACSU (P12425), GLN1A_CLOSA (P10656), 
GLN1A_LACDE (P45627), GLN1A_LACLA (Q9CDL9), GLN1A_STAAC (Q5HGC3), 
GLN1A_STAAM (P60890), GLN1A_STAAN (P99095), GLN1A_STAAR (Q6GHC6), 
GLN1A_STAAS (Q6G9Q4), GLN1A_STAAU (P0A040), GLN1A_STAAW (P0A039), 
GLN1A_STAEQ (Q5HPN2), GLN1A_STAES (Q8CSR8), GLN1A_THEMA (P36205), 
GLN1B_ACIFR (P07804), GLN1B_AZOBR (P10583), GLN1B_AZOC5 (P94126), 
GLN1B_AZOVI (P22248), GLN1B_BRADU (P05457), GLN1B_CERSP (P43518), 
GLN1B_ECO57 (P0A9C7), GLN1B_ECOL6 (P0A9C6), GLN1B_ECOLI (P0A9C5), 
GLN1B_FRAAL (P46033), GLN1B_HAEIN (P43794), GLN1B_METCA (P15124), 
GLN1B_MICDP (P33035), GLN1B_MYCBO (P0A591), GLN1B_MYCS2 (A0R079), 
GLN1B_MYCTO (P9WN38), GLN1B_MYCTU (P9WN39), GLN1B_NEIGO (P25821), 
GLN1B_NOSS1 (P00964), GLN1B_PASMU (Q9CLP2), GLN1B_PICP2 (P28605), 
GLN1B_PROHU (P28786), GLN1B_PSEAE (Q9HU65), GLN1B_PSETA (Q3V5W6), 
GLN1B_RHIME (Q59747), GLN1B_RHOCA (P13499), GLN1B_SALTI (P0A1P7), 
GLN1B_SALTY (P0A1P6), GLN1B_SHIFL (P0A9C8), GLN1B_STRCO (P15106), 
GLN1B_STRFL (P77958), GLN1B_STRVR (Q05542), GLN1B_SYNY3 (P77961), 
GLN1B_VIBAL (P19904), GLN1B_VIBCH (Q9KNJ2), GLNA1_ALNGL (O04867), 
GLNA1_CHLRE (Q42688), GLNA1_DAUCA (O22504), GLNA1_DROME (P20477), 
GLNA1_LOTJA (Q42899), GLNA1_MAIZE (P38559), GLNA1_MEDSA (P04078), 
GLNA1_METMA (Q8PY99), GLNA1_PEA   (P08282), GLNA1_PHAVU (P04770), 
GLNA1_SOYBN (P24099), GLNA1_VITVI (P51118), GLNA2_ARATH (Q43127), 
GLNA2_BRADU (P04772), GLNA2_CHLRE (Q42689), GLNA2_DAUCA (O22506), 
GLNA2_DROME (P20478), GLNA2_FRAAL (P20805), GLNA2_HORVU (P13564), 
GLNA2_MAIZE (P38560), GLNA2_MEDSA (Q9XQ94), GLNA2_ORYSJ (P14655), 
GLNA2_PEA   (P08281), GLNA2_PHAVU (P04771), GLNA2_RHILP (Q02154), 
GLNA2_RHIML (P45626), GLNA2_SOYBN (O82560), GLNA2_STRHY (P22878), 
GLNA2_STRVR (P19432), GLNA2_VITVI (P51119), GLNA3_HALMT (I3R176), 
GLNA3_HORVU (Q06378), GLNA3_LUPAN (P14636), GLNA3_MAIZE (P38561), 
GLNA3_MEDSA (Q43785), GLNA3_PEA   (P07694), GLNA3_PHAVU (P00965), 
GLNA4_MAIZE (P38562), GLNA4_PEA   (Q43066), GLNA4_PHAVU (P15102), 
GLNA5_MAIZE (P38563), GLNAC_BRANA (Q42624), GLNAC_MAIZE (P25462), 
GLNA_ACOCA  (Q9QY94), GLNA_AGABI  (O00088), GLNA_AMAMU  (Q8X169), 
GLNA_BOVIN  (P15103), GLNA_CAEEL  (P34497), GLNA_CANGA  (Q6FMT6), 
GLNA_CANLF  (Q8HZM5), GLNA_CHICK  (P16580), GLNA_COLGL  (Q12613), 
GLNA_CRIGR  (P04773), GLNA_CRYNB  (P0CN85), GLNA_CRYNJ  (P0CN84), 
GLNA_DEBHA  (Q6B4U7), GLNA_EMENI  (Q96V52), GLNA_EREGS  (Q75BT9), 
GLNA_FUSFU  (Q9C2U9), GLNA_FUSSH  (Q9UUN6), GLNA_HALSA  (Q9HNI2), 
GLNA_HALVD  (P43386), GLNA_HEBCY  (Q96UV5), GLNA_HUMAN  (P15104), 
GLNA_KLULA  (Q874T6), GLNA_LACSA  (P23712), GLNA_LUPLU  (P52782), 
GLNA_MACFA  (Q4R7U3), GLNA_METJA  (Q60182), GLNA_METMP  (O59648), 
GLNA_METTH  (O27612), GLNA_METVO  (P21154), GLNA_MIMIV  (Q5UR44), 
GLNA_MOUSE  (P15105), GLNA_NEUCR  (Q86ZF9), GLNA_NICPL  (P12424), 
GLNA_PANAR  (Q04831), GLNA_PIG(P46410), GLNA_PINSY  (P52783), 
GLNA_PYRAB  (Q9UY99), GLNA_PYRFU  (Q05907), GLNA_PYRHO  (O58097), 
GLNA_PYRWO  (P36687), GLNA_RAT(P09606), GLNA_SACS2  (P23794), 
GLNA_SCHPO  (Q09179), GLNA_SQUAC  (P41320), GLNA_SUIBO  (Q8J1R3), 
GLNA_SULAC  (Q9HH09), GLNA_THEKO  (O08467), GLNA_THET8  (Q5SIP0), 
GLNA_TUBBO  (Q86ZU6), GLNA_VIGAC  (P32289), GLNA_XENLA  (P51121), 
GLNA_YARLI  (Q6C3E0), GLNA_YEAST  (P32288)
» more

UniProtKB/Swiss-Prot
False negative sequences		 28 sequences 

GLN1A_MYCBO (P64246), GLN1A_MYCS2 (A0R083), GLN1A_MYCTO (P9WN36), 

GLN1A_MYCTU (P9WN37), GLN1B_AQUAE (O66514), GLN1B_HELPJ (Q9ZLW5), 
GLN1B_HELPY (P94845), GLN1B_RHILV (P09826), GLNA1_DICDI (Q86B00), 
GLNA2_DICDI (P0C7B6), GLNA2_HALMT (I3R584), GLNA2_STRCO (Q9RDS6), 
GLNA3_BACFR (P15623), GLNA3_BUTFI (Q05650), GLNA3_DICDI (Q54WR9), 
GLNA3_RHILP (P31592), GLNA3_RHIME (O87393), GLNA3_STRCO (Q9KZC7), 
GLNA4_STRCO (O88070), GLNA_ARCFU  (O29313), GMAS_METMY  (A9ZPH9), 
GMAS_METUF  (F5RH07), LGSN_CANLF  (Q1ZZS1), LGSN_HUMAN  (Q5TDP6), 
LGSN_MOUSE  (Q8CIX8), LGSN_RABIT  (Q0GA40), LGSN_RAT(Q7TT51), 
PUUA_ECOLI  (P78061)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 6 sequences 

GLN1B_PHOLP (P20479), GLN1B_TRITH (P51120), GLNA2_EMIHU (P81643), 

GLNA2_PINPS (P81107), GLNA_DUNSA  (P11600), GLNA_VITSX  (P85087)
» more

UniProtKB/Swiss-Prot
False positive sequences		 12 sequences 

BGBP2_MANSE (Q8ISB6), COR2A_BOVIN (Q32LP9), COR2A_HUMAN (Q92828), 

COR2A_MOUSE (Q8C0P5), EAE_ECO11   (O31000), EAE_ECO27   (P19809), 
EAE_ECO57   (P43261), GLYAR_HALSA (Q9HHR2), SPZ2A_WHEAT (Q9ST57), 
SPZ2B_WHEAT (P93692), TRM82_ASPFC (B0XNT4), TRM82_ASPFU (Q4WJR4)
» more

PDB
[Detailed view]		 48 PDB

pdb_00001f1h; pdb_00001f52; pdb_00001fpy; pdb_00001hto; pdb_00001htq; pdb_00001lgr; pdb_00002bvc; pdb_00002d3a; pdb_00002d3b; pdb_00002d3c; pdb_00002gls; pdb_00002lgs; pdb_00002ojw; pdb_00002qc8; pdb_00002uu7; pdb_00002wgs; pdb_00002whi; pdb_00003fky; pdb_00003ng0; pdb_00003zxr; pdb_00003zxv; pdb_00004acf; pdb_00004lnf; pdb_00004lni; pdb_00004lnk; pdb_00004lnn; pdb_00004lno; pdb_00004s0r; pdb_00004xyc; pdb_00005ldf; pdb_00007cpr; pdb_00007evt; pdb_00007u5n; pdb_00007w85; pdb_00008dnu; pdb_00008ecy; pdb_00008fbp; pdb_00008pvg; pdb_00008s59; pdb_00008tfb; pdb_00008tfc; pdb_00008tfk; pdb_00008tge; pdb_00008ufj; pdb_00008v1y; pdb_00008v22; pdb_00008xlj; pdb_00009c28
» more