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PROSITE entry PS00223


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PURL: https://purl.expasy.org/prosite/signature/PS00223

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General information about the entry

Entry name [info] ANNEXIN_1
Accession [info] PS00223
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00195

Name and characterization of the entry

Description [info] Annexin repeat signature.
Pattern [info] 
[TG]-[STV]-x(8)-[LIVMF]-x(2)-R-x(3)-[DEQNH]-x(2)-{S}-x(4)-[IFY]-x(7)-
[LIVMF]-x(3)-[LIVMF]-x(5)-{I}-x(5)-[LIVMFA]-x(2)-[LIVMF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 319 in 100 different sequences
Number of true positive hits 310 in 91 different sequences
Number of 'unknown' hits 0
Number of false positive hits 9 in 9 different sequences
Number of false negative sequences 3
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 97.18 %
Recall (true positives / (true positives + false negatives)) 99.04 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 8
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 91 sequences 

ANX10_DROME (P22465), ANX10_HUMAN (Q9UJ72), ANX10_MOUSE (Q9QZ10), 

ANX11_BOVIN (P27214), ANX11_COLLI (P14950), ANX11_DROME (Q9VXG4), 
ANX11_HUMAN (P50995), ANX11_MOUSE (P97384), ANX11_RABIT (P33477), 
ANX12_COLLI (Q92040), ANX12_HYDVU (P26256), ANX13_CANLF (Q29471), 
ANX13_HUMAN (P27216), ANX13_MOUSE (Q99JG3), ANX13_SCHJA (C1L7Y4), 
ANX1_GOSHI  (P93157), ANX22_SCHMA (C4QH88), ANX2A_XENLA (P27006), 
ANX2B_XENLA (P24801), ANX4_FRAAN  (P51074), ANXA1_BOVIN (P46193), 
ANXA1_CAVCU (P14087), ANXA1_CHICK (Q92108), ANXA1_HORSE (Q8HZM6), 
ANXA1_HUMAN (P04083), ANXA1_MOUSE (P10107), ANXA1_PANTR (A5A6M2), 
ANXA1_PIG   (P19619), ANXA1_PONAB (Q5REL2), ANXA1_RABIT (P51662), 
ANXA1_RAT   (P07150), ANXA1_RODSP (P24551), ANXA2_BOVIN (P04272), 
ANXA2_CANLF (Q6TEQ7), ANXA2_CEREL (Q2Q1M6), ANXA2_CHICK (P17785), 
ANXA2_HUMAN (P07355), ANXA2_MOUSE (P07356), ANXA2_PIG   (P19620), 
ANXA2_PONAB (Q5R5A0), ANXA2_RAT   (Q07936), ANXA2_SHEEP (A2SW69), 
ANXA3_BOVIN (Q3SWX7), ANXA3_HUMAN (P12429), ANXA3_MOUSE (O35639), 
ANXA3_RAT   (P14669), ANXA4_BOVIN (P13214), ANXA4_CANLF (P50994), 
ANXA4_HUMAN (P09525), ANXA4_MOUSE (P97429), ANXA4_PIG   (P08132), 
ANXA4_RAT   (P55260), ANXA5_BOVIN (P81287), ANXA5_CHICK (P17153), 
ANXA5_CYNPY (P70075), ANXA5_HUMAN (P08758), ANXA5_MACFA (Q4R4H7), 
ANXA5_MOUSE (P48036), ANXA5_PANTR (Q5R1W0), ANXA5_RAT   (P14668), 
ANXA6_BOVIN (P79134), ANXA6_CHICK (P51901), ANXA6_HUMAN (P08133), 
ANXA6_MOUSE (P14824), ANXA6_RAT   (P48037), ANXA7_BOVIN (P20072), 
ANXA7_DICDI (P24639), ANXA7_HUMAN (P20073), ANXA7_MACFA (Q4R5L5), 
ANXA7_MOUSE (Q07076), ANXA7_XENLA (Q92125), ANXA8_BOVIN (Q95L54), 
ANXA8_HUMAN (P13928), ANXA8_MOUSE (O35640), ANXA8_PANTR (A5A6L7), 
ANXA8_RABIT (O97529), ANXA8_RAT   (Q4FZU6), ANXA9_BOVIN (Q3ZC08), 
ANXA9_HUMAN (O76027), ANXA9_MOUSE (Q9JHQ0), ANXB9_DROME (P22464), 
ANXC1_CRYNH (J9VS56), ANXD1_ARATH (Q9SYT0), ANXD2_ARATH (Q9XEE2), 
ANXD3_ARATH (Q9SE45), ANXD5_ARATH (Q9C9X3), ANXD6_ARATH (Q9LX08), 
ANXD7_ARATH (Q9LX07), ANXD8_ARATH (Q94CK4), AXA2L_HUMAN (A6NMY6), 
AXA81_HUMAN (Q5VT79)
» more

UniProtKB/Swiss-Prot
False negative sequences		 3 sequences 

ANXA2_MESAU (C0HJG9), ANXD4_ARATH (Q9ZVJ6), ANXE1_GIAIN (Q9NFS4)


				
	

	

		UniProtKB/Swiss-Prot
'Partial' sequences		
		
			1 sequence
			


			
ANXA6_RABIT (Q9TS53)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			9 sequences
			


			
ATP6_ACTP2  (A3N2V0), ATP6_ACTP7  (B3H2P9), ATP6_ACTPJ  (B0BRX8), 

			
ATP6_HAEDU  (Q7VPP6), CBPQ_MOUSE  (Q9WVJ3), CBPQ_RAT(Q6IRK9), 
DOX1_PERHD  (W0FKI0), PLSP2_LOTGI (B3A0P3), RPOB_BDEBA  (Q6MJ09)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			103 PDB
			


			pdb_00001a8a; pdb_00001a8b; pdb_00001aei; pdb_00001aii; pdb_00001ain; pdb_00001ala; pdb_00001ann; pdb_00001anw; pdb_00001anx; pdb_00001aow; pdb_00001avc; pdb_00001avh; 
			
				pdb_00001avr; pdb_00001axn; pdb_00001bc0; pdb_00001bc1; pdb_00001bc3; pdb_00001bcw; pdb_00001bcy; pdb_00001bcz; pdb_00001bo9; pdb_00001dm5; pdb_00001g5n; pdb_00001hak; 
				pdb_00001hm6; pdb_00001hvd; pdb_00001hve; pdb_00001hvf; pdb_00001hvg; pdb_00001i4a; pdb_00001m9i; pdb_00001mcx; pdb_00001n00; pdb_00001n41; pdb_00001n42; pdb_00001n44; 
				pdb_00001sav; pdb_00001w3w; pdb_00001w45; pdb_00001w7b; pdb_00001xjl; pdb_00001ycn; pdb_00001yii; pdb_00001yj0; pdb_00002h0k; pdb_00002h0l; pdb_00002h0m; pdb_00002hyu; 
				pdb_00002hyv; pdb_00002hyw; pdb_00002ie6; pdb_00002ie7; pdb_00002q4c; pdb_00002ran; pdb_00002xo2; pdb_00002xo3; pdb_00002zhi; pdb_00002zhj; pdb_00002zoc; pdb_00003brx; 
				pdb_00004hre; pdb_00004mdu; pdb_00004mdv; pdb_00004x9p; pdb_00005lpu; pdb_00005lpx; pdb_00005lq0; pdb_00005lq2; pdb_00005n7d; pdb_00005n7f; pdb_00005n7g; pdb_00006b3i; 
				pdb_00006k22; pdb_00006k25; pdb_00006twq; pdb_00006twu; pdb_00006twx; pdb_00006twy; pdb_00007dto; pdb_00007eq7; pdb_00007nmi; pdb_00007p70; pdb_00007p71; pdb_00007p72; 
				pdb_00007p73; pdb_00007p74; pdb_00007pc3; pdb_00007pc4; pdb_00007pc5; pdb_00007pc7; pdb_00007pc8; pdb_00007pc9; pdb_00007pcb; pdb_00007qql; pdb_00007qqm; pdb_00007qqn; 
				pdb_00007zvn; pdb_00007zvx; pdb_00008ael; pdb_00008gyc; pdb_00008h0j; pdb_00008h9z; pdb_00008w5s
			
			

			» more