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PROSITE entry PS00275


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PURL: https://purl.expasy.org/prosite/signature/PS00275

Direct ScanProsite submission
General information about the entry

Entry name [info] SHIGA_RICIN
Accession [info] PS00275
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00248

Name and characterization of the entry

Description [info] Shiga/ricin ribosomal inactivating toxins active site signature.
Pattern [info] 
[LIVMA]-x-[LIVMSTA](2)-x-E-[SAGV]-[STAL]-R-[FY]-[RKNQST]-x-[LIVM]-[EQS]-
x(2)-[LIVMF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 59 in 59 different sequences
Number of true positive hits 57 in 57 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 7
Number of 'partial' sequences 12
Precision (true positives / (true positives + false positives)) 96.61 %
Recall (true positives / (true positives + false negatives)) 89.06 %

Comments [info]

Taxonomic range [info] Bacteriophages, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 5
Site [info] active_site at position 8
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 57 sequences 

ABRA_ABRPR  (P11140), ABRB_ABRPR  (Q06077), ABRC_ABRPR  (P28590), 

ABRD_ABRPR  (Q06076), AGGL_ABRPR  (Q9M6E9), AGGL_RICCO  (P06750), 
ALB3_MAIZE  (P10593), JI60_HORVU  (Q00531), NIGB_SAMNI  (P33183), 
RICI_RICCO  (P02879), RIP0_DIACA  (P24476), RIP1_BRYDI  (P33185), 
RIP1_CUCFI  (Q9FRX4), RIP1_GYNPE  (Q5F0I3), RIP1_HORVU  (P22244), 
RIP1_MOMCH  (P16094), RIP1_PHYAM  (P10297), RIP1_SAMNI  (P93543), 
RIP2_BRYDI  (P98184), RIP2_HORVU  (P04399), RIP2_MOMBA  (P29339), 
RIP2_PHYAM  (Q40772), RIP2_PHYDI  (P34967), RIP2_SAPOF  (P27559), 
RIP3_MAIZE  (P25891), RIP3_MOMCH  (P24817), RIP3_SAPOF  (P27560), 
RIP5_SAPOF  (Q41389), RIP6_SAPOF  (P20656), RIP7_SAPOF  (Q41391), 
RIP9_MAIZE  (P25892), RIPA_LUFAE  (Q00465), RIPA_PHYAM  (Q03464), 
RIPB_LUFAE  (P22851), RIPD2_PHYDI (P85208), RIPG_SURMU  (P33186), 
RIPL1_PHYDI (P84853), RIPL2_PHYDI (P84854), RIPLY_SILCH (P85101), 
RIPM_POLML  (Q9M654), RIPP_MIRJA  (P21326), RIPS_PHYAM  (P23339), 
RIPS_TRIKI  (P24478), RIPT_POLML  (Q9M653), RIPT_TRIKI  (P09989), 
RIPX_MAIZE  (P28522), RIP_CUCMO   (P84531), RIP_LUFAC   (P84530), 
SNAIB_SAMNI (Q41358), SNAIF_SAMNI (O22415), STXA_BP788  (Q779K4), 
STXA_BP933  (P09385), STXA_BPH19  (P08026), STXA_BPH30  (P10149), 
STXA_SHIDS  (Q32GM1), STXA_SHIDY  (Q9FBI2), VOLK_ADEVO  (Q70US9)
» more

UniProtKB/Swiss-Prot
False negative sequences		 7 sequences 

ML1_VISAL   (P81446), ML2_VISAL   (Q6H266), ML3_VISAL   (P82683), 

RIP1_TRIAN  (P56626), RIP4_PHYHE  (Q6EH50), RIP9_SAPOF  (Q7M1Z2), 
RIP_DRIMA   (P84786)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 12 sequences 

ARALA_ARAEL (P83572), LECA_IRIHO  (P36230), RIP1_SAPOF  (P98185), 

RIP2_DIACA  (P24477), RIP2_TRIKI  (P23029), RIP3_SURMU  (P24475), 
RIP4_SAPOF  (P27561), RIPD1_PHYDI (P86144), RIPK_TRIKI  (P16093), 
RIPS_MOMCO  (P20655), RIPX_CUCPE  (P80750), RIP_SIRGR   (P83323)
» more

UniProtKB/Swiss-Prot
False positive sequences		 2 sequences 

RIP1_GYPVA  (Q7M1L6), RIP2_GYPVA  (C0HM39)


				
	

	

		PDB
[Detailed view]		
		
			177 PDB
			


			pdb_00001abr; pdb_00001aha; pdb_00001ahb; pdb_00001ahc; pdb_00001apa; pdb_00001br5; pdb_00001br6; pdb_00001bry; pdb_00001cf5; pdb_00001d6a; pdb_00001d8v; pdb_00001dm0; 
			
				pdb_00001f8q; pdb_00001gik; pdb_00001gis; pdb_00001giu; pdb_00001ifs; pdb_00001ift; pdb_00001ifu; pdb_00001il3; pdb_00001il4; pdb_00001il5; pdb_00001il9; pdb_00001j1m; 
				pdb_00001j1q; pdb_00001j1r; pdb_00001j1s; pdb_00001j4g; pdb_00001lln; pdb_00001lp8; pdb_00001lpc; pdb_00001lpd; pdb_00001mom; pdb_00001mrg; pdb_00001mrh; pdb_00001mri; 
				pdb_00001mrj; pdb_00001mrk; pdb_00001nio; pdb_00001paf; pdb_00001pag; pdb_00001qcg; pdb_00001qci; pdb_00001qcj; pdb_00001qd2; pdb_00001qi7; pdb_00001r4p; pdb_00001r4q; 
				pdb_00001rl0; pdb_00001rtc; pdb_00001rzo; pdb_00001tcs; pdb_00001uq4; pdb_00001uq5; pdb_00002aai; pdb_00002g5x; pdb_00002ga4; pdb_00002jdl; pdb_00002jjr; pdb_00002k6h; 
				pdb_00002oqa; pdb_00002p8n; pdb_00002pjo; pdb_00002pqg; pdb_00002pqi; pdb_00002pqj; pdb_00002q3n; pdb_00002qes; pdb_00002qet; pdb_00002r2x; pdb_00002r3d; pdb_00002vs6; 
				pdb_00002z4u; pdb_00002z53; pdb_00002zr1; pdb_00003bwh; pdb_00003ej5; pdb_00003h5k; pdb_00003hio; pdb_00003ktz; pdb_00003ku0; pdb_00003lc9; pdb_00003le7; pdb_00003mk9; 
				pdb_00003px8; pdb_00003px9; pdb_00003rti; pdb_00003rtj; pdb_00003srp; pdb_00004esi; pdb_00004fb9; pdb_00004fba; pdb_00004fbb; pdb_00004fbc; pdb_00004fbh; pdb_00004huo; 
				pdb_00004hup; pdb_00004hv3; pdb_00004hv7; pdb_00004imv; pdb_00004kuc; pdb_00004lgp; pdb_00004lgr; pdb_00004lgs; pdb_00004lhj; pdb_00004lhq; pdb_00004mx1; pdb_00004mx5; 
				pdb_00004q2v; pdb_00004yp2; pdb_00004z9k; pdb_00005boz; pdb_00005cf9; pdb_00005ddz; pdb_00005e1h; pdb_00005gu4; pdb_00005j56; pdb_00005j57; pdb_00005sv3; pdb_00005u4l; 
				pdb_00005u4m; pdb_00005z37; pdb_00005z3i; pdb_00005z3j; pdb_00006cwg; pdb_00006loq; pdb_00006lor; pdb_00006lov; pdb_00006low; pdb_00006loy; pdb_00006loz; pdb_00006lp0; 
				pdb_00006obc; pdb_00006obe; pdb_00006obg; pdb_00006obm; pdb_00006obo; pdb_00006oca; pdb_00006ocd; pdb_00006urw; pdb_00006urx; pdb_00006ury; pdb_00007kbi; pdb_00007kbk; 
				pdb_00007kc9; pdb_00007kd0; pdb_00007kd2; pdb_00007kdm; pdb_00007kdu; pdb_00007mln; pdb_00007mlo; pdb_00007mlp; pdb_00007mlt; pdb_00007tgf; pdb_00007tgi; pdb_00007th2; 
				pdb_00007th3; pdb_00007ujj; pdb_00007xzs; pdb_00007xzt; pdb_00007xzu; pdb_00007xzw; pdb_00007y02; pdb_00007y03; pdb_00007y05; pdb_00007y06; pdb_00007y07; pdb_00007y08; 
				pdb_00007y4k; pdb_00007y4m; pdb_00008i7p; pdb_00008sz2; pdb_00008t9v; pdb_00008tab; pdb_00008tad; pdb_00008tfh; pdb_00008tfl
			
			

			» more