PROSITE logo
Black ribbon
We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS00352


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
PURL: https://purl.expasy.org/prosite/signature/PS00352

Direct ScanProsite submission
General information about the entry

Entry name [info] CSD_1
Accession [info] PS00352
Entry type [info] PATTERN
Date [info] 01-NOV-1990 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00304

Name and characterization of the entry

Description [info] Cold-shock (CSD) domain signature.
Pattern [info] 
[FYKH]-G-[FL]-[IL]-x(6,7)-[DER]-[LIVM]-[FQ]-x-H-x-[STKR]-x-[LIVMFYC].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 179 in 168 different sequences
Number of true positive hits 178 in 167 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 1
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 99.44 %
Recall (true positives / (true positives + false negatives)) 99.44 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 4
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 167 sequences 

CAPA_PSEFR  (P72188), CAPB_PSEFR  (P0A106), CAPB_PSESM  (P0A105), 

CHSP1_HUMAN (Q9Y2V2), CHSP1_MOUSE (Q9CR86), CHSP1_RAT   (Q9WU49), 
CSDC2_HUMAN (Q9Y534), CSDC2_MOUSE (Q91YQ3), CSDC2_RAT   (Q63430), 
CSDE1_HUMAN (O75534), CSDE1_MOUSE (Q91W50), CSDE1_RAT   (P18395), 
CSP1_ARATH  (O65639), CSP1_LACPL  (P71478), CSP2_ARATH  (Q41188), 
CSP2_LACPL  (P96349), CSP3_ARATH  (Q94C69), CSP4_ARATH  (Q38896), 
CSP7_STRCL  (Q01761), CSPA_AERHY  (Q44078), CSPA_AERSA  (Q44317), 
CSPA_BACAN  (Q81TW8), CSPA_BACCE  (Q45096), CSPA_BACCR  (Q81GQ6), 
CSPA_BORBR  (P0A353), CSPA_BORPA  (P0A354), CSPA_BORPE  (P0A352), 
CSPA_CITFR  (Q46051), CSPA_ECO57  (P0A9Y1), CSPA_ECOL6  (P0A9Y0), 
CSPA_ECOLI  (P0A9X9), CSPA_KLEAK  (Q46664), CSPA_KLEPN  (Q48493), 
CSPA_LISIN  (P0A356), CSPA_LISMO  (P0A355), CSPA_MICLC  (O30875), 
CSPA_MYCBO  (P63849), CSPA_MYCS2  (A0R5E1), CSPA_MYCTO  (P9WP74), 
CSPA_MYCTU  (P9WP75), CSPA_PHOLD  (Q51929), CSPA_PHOPO  (Q52287), 
CSPA_PSEAE  (P95459), CSPA_RHIME  (Q9Z3S6), CSPA_RICBR  (Q1RHK6), 
CSPA_RICCN  (Q92GV1), CSPA_RICFE  (Q4UMU5), CSPA_RICPR  (Q9ZCP9), 
CSPA_RICTY  (Q68W69), CSPA_SALEN  (P0A9Y5), CSPA_SALTI  (P0A9Y3), 
CSPA_SALTY  (P0A9Y2), CSPA_SALVI  (Q56178), CSPA_SHEVD  (Q9S1B7), 
CSPA_SHIBO  (Q53816), CSPA_SHIFL  (P0A9Y4), CSPA_STAA3  (Q2FH36), 
CSPA_STAA8  (Q2FYN2), CSPA_STAAB  (Q2YY16), CSPA_STAAC  (Q5HG18), 
CSPA_STAAM  (Q7A2R8), CSPA_STAAN  (Q7A5P3), CSPA_STAAR  (Q6GH06), 
CSPA_STAAS  (Q6G9F9), CSPA_STAAW  (Q7A0X3), CSPA_STAEQ  (Q5HPE0), 
CSPA_STAES  (Q8CP90), CSPA_STAHJ  (Q4L6A7), CSPA_STAS1  (Q49XK3), 
CSPA_STIAD  (P72366), CSPA_STRDY  (Q53984), CSPA_STRP1  (P0C0F1), 
CSPA_STRP3  (P0DA48), CSPA_STRP6  (Q5X9L4), CSPA_STRP8  (P0A361), 
CSPA_STRPQ  (P0DA49), CSPA_STRPY  (P0C0F0), CSPA_VIBCH  (Q9KN00), 
CSPA_YEREN  (Q56922), CSPB_BACCE  (Q45097), CSPB_BACCL  (P41016), 
CSPB_BACSU  (P32081), CSPB_ECOLI  (P36995), CSPB_GEOSE  (P42016), 
CSPB_LISIN  (P0A358), CSPB_LISMO  (P0A357), CSPB_SPOGL  (P41018), 
CSPB_YEREN  (P0A363), CSPB_YERPE  (P0A362), CSPC_BACAN  (P62169), 
CSPC_BACCE  (P62170), CSPC_BACCR  (P62171), CSPC_BACSU  (P39158), 
CSPC_BUCAI  (P57407), CSPC_ECO57  (P0A9Y8), CSPC_ECOL6  (P0A9Y7), 
CSPC_ECOLI  (P0A9Y6), CSPC_ECOLW  (E0J500), CSPC_SALTI  (P0A9Z0), 
CSPC_SALTY  (P0A9Y9), CSPC_SHIFL  (Q83RI9), CSPD_BACAN  (Q81K90), 
CSPD_BACCE  (Q45099), CSPD_BACCR  (Q816H3), CSPD_BACSU  (P51777), 
CSPD_ECO57  (P0A970), CSPD_ECOL6  (P0A969), CSPD_ECOLI  (P0A968), 
CSPD_HAEIN  (P46449), CSPD_SHIFL  (P0A971), CSPD_VIBCH  (Q9KSW4), 
CSPE_BACAN  (Q81QK2), CSPE_BACCE  (Q45100), CSPE_BACCR  (Q81DK5), 
CSPE_BUCAI  (P63237), CSPE_BUCAP  (P63238), CSPE_BUCBP  (Q89A90), 
CSPE_ECO57  (P0A974), CSPE_ECOL6  (P0A973), CSPE_ECOLI  (P0A972), 
CSPE_ECOLW  (E0J1Q3), CSPE_SHIFL  (P0A975), CSPF_ECOL6  (P0A977), 
CSPF_ECOLI  (P0A976), CSPF_STRCO  (P48859), CSPG_ECO57  (P0A980), 
CSPG_ECOL6  (P0A979), CSPG_ECOLI  (P0A978), CSPG_SHEVD  (Q9S170), 
CSPG_SHIFL  (P0A981), CSPH_ECO57  (P0A984), CSPH_ECOL6  (P0A983), 
CSPH_ECOLI  (P0A982), CSPH_SALTI  (P0A1E0), CSPH_SALTY  (P0A1D9), 
CSPH_SHIFL  (P0A985), CSPI_ECOL6  (P0A987), CSPI_ECOLI  (P0A986), 
CSPJ_SALTI  (P58726), CSPJ_SALTS  (E1WGN1), CSPJ_SALTY  (P0CL01), 
CSP_AQUAE   (O67327), CSP_ARTGO   (P54584), CSP_THEMA   (O54310), 
GRP2_NICSY  (P27484), TAPA_PSEFR  (P72191), TAPB_PSEFR  (P72192), 
UNR_DROME   (B7Z0E2), Y4CH_SINFN  (P55390), Y9705_DROME (Q9VVA0), 
YB3_XENLA   (Q00436), YBOX1_BOVIN (P67808), YBOX1_CHICK (Q06066), 
YBOX1_DANRE (B5DE31), YBOX1_HUMAN (P67809), YBOX1_MOUSE (P62960), 
YBOX1_RABIT (Q28618), YBOX1_RAT   (P62961), YBOX1_XENLA (P21573), 
YBOX2_HUMAN (Q9Y2T7), YBOX2_MOUSE (Q9Z2C8), YBOX3_HUMAN (P16989), 
YBOX3_MOUSE (Q9JKB3), YBOX3_RAT   (Q62764), YBOXH_APLCA (P41824), 
YBX2A_XENLA (P21574), YBX2B_XENLA (P45441)
» more

UniProtKB/Swiss-Prot
False negative sequences		 1 sequence 

CS72_SALH5  (P0DV90)


				
	

	

		UniProtKB/Swiss-Prot
'Partial' sequences		
		
			2 sequences
			


			
CSDE1_CAVPO (P29174), CSPS_STRTR  (P81622)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			1 sequence
			


			
DSBB_BLOPB  (Q492M6)


				
	

	

		PDB
[Detailed view]		
		
			56 PDB
			


			pdb_00001c9o; pdb_00001csp; pdb_00001csq; pdb_00001g6p; pdb_00001h95; pdb_00001hz9; pdb_00001hza; pdb_00001hzb; pdb_00001hzc; pdb_00001i5f; pdb_00001mjc; pdb_00001nmf; 
			
				pdb_00001nmg; pdb_00001wfq; pdb_00001x65; pdb_00002es2; pdb_00002f52; pdb_00002hax; pdb_00002i5l; pdb_00002i5m; pdb_00002l15; pdb_00002lxj; pdb_00002lxk; pdb_00002ytx; 
				pdb_00002yty; pdb_00003aqq; pdb_00003mef; pdb_00003pf4; pdb_00003pf5; pdb_00004qqb; pdb_00005jx4; pdb_00005yts; pdb_00005ytt; pdb_00005ytv; pdb_00005ytx; pdb_00006a6j; 
				pdb_00006a6l; pdb_00006ktc; pdb_00006kug; pdb_00006lmr; pdb_00006lms; pdb_00006szz; pdb_00006t00; pdb_00006y4h; pdb_00006y6e; pdb_00006y6m; pdb_00007f3i; pdb_00007f3j; 
				pdb_00007f3k; pdb_00007f3l; pdb_00007zhh; pdb_00007zhr; pdb_00008h1i; pdb_00008rxe; pdb_00008tg0; pdb_00008xyf
			
			

			» more