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PROSITE entry PS00353


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General information about the entry

Entry name [info] HMG_BOX_1
Accession [info] PS00353
Entry type [info] PATTERN
Date [info] 01-NOV-1990 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00305

Name and characterization of the entry

Description [info] HMG box A DNA-binding domain signature.
Pattern [info]
[FI]-S-[KR]-K-C-x-[EK]-R-W-K-T-[MV].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.


Total number of hits 25 in 25 different sequences
Number of true positive hits 25 in 25 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 29
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 46.30 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
25 sequences

HMG2_DROME  (Q24537), HMGB1_BOVIN (P10103), HMGB1_CALJA (B0CM99), 
HMGB1_CANLF (Q6YKA4), HMGB1_CHICK (Q9YH06), HMGB1_CRIGR (P07156), 
HMGB1_HORSE (Q08IE6), HMGB1_HUMAN (P09429), HMGB1_MACFA (Q4R844), 
HMGB1_MOUSE (P63158), HMGB1_PAPAN (A9RA84), HMGB1_PIG   (P12682), 
HMGB1_PLEMO (B1MTB0), HMGB1_RAT   (P63159), HMGB2_BOVIN (P40673), 
HMGB2_CHICK (P26584), HMGB2_HUMAN (P26583), HMGB2_MOUSE (P30681), 
HMGB2_PIG   (P17741), HMGB2_RAT   (P52925), HMGB3_BOVIN (Q32L31), 
HMGB3_CHICK (P40618), HMGB3_HUMAN (O15347), HMGB3_MOUSE (O54879), 
HMGT_ONCMY  (P07746)
» more

UniProtKB/Swiss-Prot
False negative sequences
29 sequences

HGB1A_HUMAN (B2RPK0), HM20A_CHICK (Q5ZKF4), HM20A_HUMAN (Q9NP66), 
HM20A_MOUSE (Q9DC33), HM20A_XENLA (Q6AZF8), HM20A_XENTR (Q6DIJ5), 
HM20B_BOVIN (Q32L68), HM20B_HUMAN (Q9P0W2), HM20B_MOUSE (Q9Z104), 
HMGB4_BOVIN (Q32L34), HMGB4_HUMAN (Q8WW32), HMGB4_MOUSE (Q6P8W9), 
HMO1_YEAST  (Q03973), MATA2_CANAL (Q71U11), MATA2_KLULA (Q9HG13), 
MATA2_YARLL (O93958), MATB_NEUCS  (P36981), MATD_NEUCR  (Q10116), 
NHP10_YEAST (Q03435), SMCE1_HUMAN (Q969G3), SMCE1_MOUSE (O54941), 
SMCE1_RAT   (Q56A18), SOX21_MOUSE (Q811W0), TOX3_HUMAN  (O15405), 
TOX3_MOUSE  (Q80W03), TOX3_RAT(B7SBD2), TOX_HUMAN   (O94900), 
TOX_MOUSE   (Q66JW3), VF401_IIV3  (Q196Z2)
» more

PDB
[Detailed view]
21 PDB

1AAB; 1CKT; 1J3X; 2EQZ; 2LY4; 2RTU; 2YRQ; 4QR9; 5ZDZ; 5ZE0; 5ZE1; 5ZE2; 6CG0; 6CIJ; 6CIK; 6CIL; 6CIM; 6OEM; 6OEN; 6OEO; 6OER
» more