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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS00398


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PURL: https://purl.expasy.org/prosite/signature/PS00398

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General information about the entry

Entry name [info] RECOMBINASES_2
Accession [info] PS00398
Entry type [info] PATTERN
Date [info] 01-NOV-1990 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00334

Name and characterization of the entry

Description [info] Site-specific recombinases signature 2.
Pattern [info] 
G-[DE]-x(2)-[LIVM]-{E}-x-{V}-[LIVM]-[DT]-R-[LIVM]-[GSA].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 37 in 37 different sequences
Number of true positive hits 32 in 32 different sequences
Number of 'unknown' hits 0
Number of false positive hits 5 in 5 different sequences
Number of false negative sequences 8
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 86.49 %
Recall (true positives / (true positives + false negatives)) 80.00 %

Comments [info]

Taxonomic range [info] Bacteriophages, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 32 sequences 

BIN3_STAAU  (P20384), BINL_STAAU  (P18358), BINR_STAAU  (P19241), 

CIN_BPP1(P10311), CIN_BPP7(P21703), GIN_BPD10   (Q38199), 
GIN_BPMU(P03015), HIN_SALAE   (Q02869), HIN_SALTY   (P03013), 
PARA4_ECOLX (P22996), PINE_ECOLI  (P03014), PINQ_ECOLI  (P77170), 
PINR_ECOL6  (P0ADI1), PINR_ECOLI  (P0ADI0), RES4_ECOLX  (P13606), 
RES_CLOPE   (Q93MD2), RES_CLOPF   (P07945), STBA_PSEUB  (Q52563), 
TNPT_PSEPU  (P30739), TNR0_ECOLX  (P05823), TNR1_ECOLI  (P03012), 
TNR2_ECOLX  (P04130), TNR3_ECOLX  (P0ADI2), TNR3_KLEPN  (P0ADI3), 
TNR4_KLEPN  (P21424), TNR5_PSEAI  (P06691), TNR7_ECOLX  (P0C1G2), 
TNR7_ENTFL  (P06693), TNR7_PSEPU  (P0C1G3), UVP1_ECOLX  (P18957), 
Y4CG_SINFN  (P55389), Y4LS_SINFN  (P55559)
» more

UniProtKB/Swiss-Prot
False negative sequences		 8 sequences 

CISA_BACSU  (P17867), ISTA_PSEAI  (P15025), TNR6_ENTFC  (Q06237), 

YL103_MIMIV (Q5UPI1), YNEB_BACSU  (Q45057), YOKA_BACSU  (O32006), 
YR080_MIMIV (Q5UPF4), YR771_MIMIV (Q5UPQ7)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

PINH_ECOLI  (P76611)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			5 sequences
			


			
ABCE_ASPFU  (Q4WA92), FOLD_ALCBS  (Q0VQ92), KMT2D_HUMAN (O14686), 

			
NTE1_CANGA  (Q6FKJ1), SP4A_CLOD6  (Q182W3)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			18 PDB
			


			pdb_00001gdr; pdb_00001gdt; pdb_00001ght; pdb_00001hx7; pdb_00001zr2; pdb_00001zr4; pdb_00002gm4; pdb_00002r0q; pdb_00002rsl; pdb_00003pkz; pdb_00003uj3; pdb_00004m6f; 
			
				pdb_00005c31; pdb_00005c32; pdb_00005c34; pdb_00005c35; pdb_00005cy1; pdb_00005cy2
			
			

			» more