PROSITE entry PS00479

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General information about the entry

Entry name [info]	ZF_DAG_PE_1
Accession [info]	PS00479
Entry type [info]	PATTERN
Date [info]	01-MAY-1991 CREATED; 01-NOV-1997 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00379

Name and characterization of the entry

Description [info]	Zinc finger phorbol-ester/DAG-type signature.
Pattern [info]	H-x-[LIVMFYW]-x(8,11)-C-x(2)-C-x(3)-[LIVMFC]-x(5,10)-C-x(2)-C-x(4)-[HD]- x(2)-C-x(5,9)-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_04 which contains 571'864 sequence entries.

Total number of hits	342 in 246 different sequences
Number of true positive hits	342 in 246 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	42
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	89.06 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	3
Site [info]	zinc at position 1
Site [info]	zinc at position 5
Site [info]	zinc at position 7
Site [info]	zinc at position 11
Site [info]	zinc at position 13
Site [info]	zinc at position 15
Site [info]	zinc at position 17
Site [info]	zinc at position 19
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

246 sequences

AKP13_HUMAN (Q12802), AKP13_MOUSE (E9Q394), AKP13_RAT   (F1M3G7),

APKC_DROME  (A1Z9X0), ARAF_HUMAN  (P10398), ARAF_MOUSE  (P04627), 
ARAF_PIG(O19004), ARAF_RAT(P14056), ARG28_HUMAN (Q8N1W1), 
ARG28_MOUSE (P97433), ARG28_RAT   (P0C6P5), ARHG2_CANLF (Q865S3), 
ARHG2_HUMAN (Q92974), ARHG2_MOUSE (Q60875), ARHG2_PIG   (B2DCZ9), 
ARHG2_RAT   (Q5FVC2), BRAF_CHICK  (Q04982), BRAF_COTJA  (P34908), 
BRAF_HUMAN  (P15056), BRAF_MOUSE  (P28028), BZZ1_SCHPO  (Q09746), 
CHIN_BOVIN  (Q17QN0), CHIN_HUMAN  (P15882), CHIN_MOUSE  (Q91V57), 
CHIN_RAT(P30337), CHIO_HUMAN  (P52757), CHIO_MOUSE  (Q80XD1), 
CHIO_RAT(Q03070), CTRO_HUMAN  (O14578), CTRO_MOUSE  (P49025), 
CTRO_RAT(E9PSL7), DEFI8_BOVIN (A5PJM7), DEFI8_HUMAN (Q6ZN54), 
DEFI8_MOUSE (Q99J78), DEFI8_RAT   (Q4V8I4), DEFI8_XENTR (Q6DJB3), 
DFI8A_XENLA (Q6DDJ3), DFI8B_XENLA (Q7T0P6), DGK1_DROME  (Q01583), 
DGK3_CAEEL  (Q03603), DGKA_BOVIN  (A0JN54), DGKA_DICDI  (P34125), 
DGKA_HUMAN  (P23743), DGKA_MOUSE  (O88673), DGKA_PIG(P20192), 
DGKA_RAT(P51556), DGKB_HUMAN  (Q9Y6T7), DGKB_MOUSE  (Q6NS52), 
DGKB_RAT(P49621), DGKD_HUMAN  (Q16760), DGKD_MOUSE  (E9PUQ8), 
DGKE_HUMAN  (P52429), DGKE_MOUSE  (Q9R1C6), DGKG_HUMAN  (P49619), 
DGKG_MOUSE  (Q91WG7), DGKG_RAT(P49620), DGKH_DROAN  (B3LXF2), 
DGKH_DROER  (B3NYS4), DGKH_DROGR  (B4JHJ7), DGKH_DROME  (A8JQ65), 
DGKH_DROMO  (B4K6T8), DGKH_DROSE  (B4I4Y1), DGKH_DROSI  (B4R0A5), 
DGKH_DROYA  (B4PRE2), DGKH_HUMAN  (Q86XP1), DGKH_MESAU  (Q64398), 
DGKH_MOUSE  (D3YXJ0), DGKK_HUMAN  (Q5KSL6), DGKQ_HUMAN  (P52824), 
DGKQ_MOUSE  (Q6P5E8), DGKQ_RAT(D3ZEY4), DKF1_CAEBR  (A8XWC4), 
DKF1_CAEEL  (Q9XUJ7), DKF2_CAEBR  (A8XQD5), DKF2_CAEEL  (O45818), 
GEK_DROME   (Q9W1B0), GMIP_HUMAN  (Q9P107), GMIP_MOUSE  (Q6PGG2), 
GRP1_HUMAN  (O95267), GRP1_MOUSE  (Q9Z1S3), GRP1_RAT(Q9R1K8), 
GRP1_XENLA  (Q6NTL4), GRP1_XENTR  (A4IJ06), GRP2A_XENLA (Q32N25), 
GRP2B_XENLA (Q6DCK3), GRP2_BOVIN  (A6N9I4), GRP2_HUMAN  (Q7LDG7), 
GRP2_MOUSE  (Q9QUG9), GRP2_RAT(P0C643), GRP3_HUMAN  (Q8IV61), 
GRP4_BOVIN  (Q1LZ97), GRP4_HUMAN  (Q8TDF6), GRP4_MOUSE  (Q8BTM9), 
HMHA1_HUMAN (Q92619), HMHA1_MOUSE (Q3TBD2), HMHA1_PONAB (Q5RB40), 
HMHA1_XENLA (Q6DE55), KPC1B_CAEEL (P34885), KPC1_APLCA  (Q16974), 
KPC1_ASPNG  (Q00078), KPC1_CAEEL  (P34722), KPC1_CANAX  (P43057), 
KPC1_COCHE  (O42632), KPC1_DROME  (P05130), KPC1_HYPJE  (Q99014), 
KPC1_LYTPI  (Q25378), KPC1_NEUCR  (P87253), KPC1_YEAST  (P24583), 
KPC2_APLCA  (Q16975), KPC2_CAEEL  (P90980), KPC2_DROME  (P13677), 
KPC3_CAEBR  (A8WUG4), KPC3_CAEEL  (Q19266), KPC3_DROME  (P13678), 
KPC4_DROME  (P83099), KPCA_BOVIN  (P04409), KPCA_HUMAN  (P17252), 
KPCA_MOUSE  (P20444), KPCA_RABIT  (P10102), KPCA_RAT(P05696), 
KPCB_BOVIN  (P05126), KPCB_DANRE  (Q7SY24), KPCB_HUMAN  (P05771), 
KPCB_MOUSE  (P68404), KPCB_RABIT  (P05772), KPCB_RAT(P68403), 
KPCB_XENLA  (Q7LZQ8), KPCB_XENTR  (A8KBH6), KPCD1_HUMAN (Q15139), 
KPCD1_MOUSE (Q62101), KPCD1_RAT   (Q9WTQ1), KPCD2_HUMAN (Q9BZL6), 
KPCD2_MOUSE (Q8BZ03), KPCD2_RAT   (Q5XIS9), KPCD3_HUMAN (O94806), 
KPCD3_MOUSE (Q8K1Y2), KPCD_CANLF  (Q5PU49), KPCD_HUMAN  (Q05655), 
KPCD_MOUSE  (P28867), KPCD_RAT(P09215), KPCE_HUMAN  (Q02156), 
KPCE_MOUSE  (P16054), KPCE_RABIT  (P10830), KPCE_RAT(P09216), 
KPCG_BOVIN  (P05128), KPCG_HUMAN  (P05129), KPCG_MACFA  (Q4R4U2), 
KPCG_MOUSE  (P63318), KPCG_RABIT  (P10829), KPCG_RAT(P63319), 
KPCI_DANRE  (Q90XF2), KPCI_HUMAN  (P41743), KPCI_MOUSE  (Q62074), 
KPCI_PONAB  (Q5R4K9), KPCI_RAT(F1M7Y5), KPCL_HUMAN  (P24723), 
KPCL_MOUSE  (P23298), KPCL_RAT(Q64617), KPCT_HUMAN  (Q04759), 
KPCT_MOUSE  (Q02111), KPCT_RAT(Q9WTQ0), KPCZ_HUMAN  (Q05513), 
KPCZ_MOUSE  (Q02956), KPCZ_RABIT  (O19111), KPCZ_RAT(P09217), 
KRAF1_CAEBR (Q61UC4), KRAF1_CAEEL (Q07292), KRAF1_DROME (P11346), 
KSR1_HUMAN  (Q8IVT5), KSR1_MOUSE  (Q61097), KSR2_HUMAN  (Q6VAB6), 
KSR2_MOUSE  (Q3UVC0), MRCKA_HUMAN (Q5VT25), MRCKA_MOUSE (Q3UU96), 
MRCKA_RAT   (O54874), MRCKB_HUMAN (Q9Y5S2), MRCKB_MOUSE (Q7TT50), 
MRCKB_RAT   (Q7TT49), MRCKG_HUMAN (Q6DT37), MRCKG_MOUSE (Q80UW5), 
MRCK_CAEEL  (O01583), MY9AA_DANRE (E7EZG2), MY9AB_DANRE (E7F3F0), 
MYO9A_HUMAN (B2RTY4), MYO9A_MOUSE (Q8C170), MYO9A_RAT   (Q9Z1N3), 
MYO9B_HUMAN (Q13459), MYO9B_MOUSE (Q9QY06), MYO9B_RAT   (Q63358), 
PCK1_SCHPO  (P36582), PCK2_SCHPO  (P36583), PKCA_ASPFU  (Q4WVG0), 
RAF1_BOVIN  (A7E3S4), RAF1_CHICK  (P05625), RAF1_HUMAN  (P04049), 
RAF1_MOUSE  (Q99N57), RAF1_PONAB  (Q5R5M7), RAF1_RAT(P11345), 
RAF1_XENLA  (P09560), RASF1_CAEEL (Q22744), RASF1_MOUSE (Q99MK9), 
RASF5_HUMAN (Q8WWW0), RASF5_MOUSE (Q5EBH1), RASF5_RAT   (O35141), 
RG84C_DROME (P40809), RGAP1_HUMAN (Q9H0H5), RGAP1_MOUSE (Q9WVM1), 
RHG29_BOVIN (A7YY57), RHG29_DANRE (Q6PCS4), RHG29_HUMAN (Q52LW3), 
RHG29_MOUSE (Q8CGF1), RHG29_RAT   (Q5PQJ5), STAC2_HUMAN (Q6ZMT1), 
STAC2_MOUSE (Q8R1B0), STAC3_DANRE (Q6DBR6), STAC3_HUMAN (Q96MF2), 
STAC3_MOUSE (Q8BZ71), STAC3_XENTR (Q68F99), STAC_BOVIN  (A0JNJ1), 
STAC_HUMAN  (Q99469), STAC_MOUSE  (P97306), TENS1_BOVIN (Q9GLM4), 
TENS1_HUMAN (Q9HBL0), TENS1_MOUSE (E9Q0S6), TENS2_HUMAN (Q63HR2), 
TENS2_MOUSE (Q8CGB6), UN13A_HUMAN (Q9UPW8), UN13A_MOUSE (Q4KUS2), 
UN13A_RAT   (Q62768), UN13B_HUMAN (O14795), UN13B_MOUSE (Q9Z1N9), 
UN13B_RAT   (Q62769), UN13C_HUMAN (Q8NB66), UN13C_MOUSE (Q8K0T7), 
UN13C_RAT   (Q62770), UNC13_CAEEL (P27715), VAV2_HUMAN  (P52735), 
VAV2_MOUSE  (Q60992), VAV3_HUMAN  (Q9UKW4), VAV3_MOUSE  (Q9R0C8), 
VAV_BOVIN   (Q08DN7), VAV_CAEEL   (Q45FX5), VAV_DROME   (Q9NHV9), 
VAV_HUMAN   (P15498), VAV_MOUSE   (P27870), VAV_RAT (P54100)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

42 sequences

ARKA_DICDI  (Q54HC6), ATX1_ARATH  (Q9C5X4), DEFI8_CAEEL (O01738),

DEFI8_DROME (Q9VTT9), DGK1_ARATH  (Q39017), DGK2_ARATH  (Q9FFN7), 
DGK2_DROME  (Q09103), DGKI_HUMAN  (O75912), DGKI_MOUSE  (D3YWQ0), 
DGKI_RAT(F1MAB7), DGKZ_HUMAN  (Q13574), DGKZ_MOUSE  (Q80UP3), 
DGKZ_RAT(O08560), FORE_DICDI  (Q5TJ57), GRP4_RAT(Q8R5I4), 
KSRA_CAEEL  (G5EFD2), KSRB_CAEEL  (G5EDA5), MTMR5_CAEEL (Q9TXP3), 
PAKD_DICDI  (Q55DD4), PDZD8_HUMAN (Q8NEN9), PDZD8_MOUSE (B9EJ80), 
PKHM1_HUMAN (Q9Y4G2), PKHM1_MOUSE (Q7TSI1), PKHM1_RAT   (Q5PQS0), 
PKHM3_HUMAN (Q6ZWE6), PKHM3_MOUSE (Q8BM47), PKHM3_XENLA (Q08AW4), 
RASF1_HUMAN (Q9NS23), RGA3_SCHPO  (O14014), ROCK1_HUMAN (Q13464), 
ROCK1_MOUSE (P70335), ROCK1_PANTR (P61584), ROCK1_RABIT (O77819), 
ROCK1_RAT   (Q63644), ROCK2_BOVIN (Q28021), ROCK2_HUMAN (O75116), 
ROCK2_MOUSE (P70336), ROCK2_RAT   (Q62868), ROCK_CAEBR  (A8WVU9), 
ROCK_CAEEL  (P92199), SNT2_SCHPO  (Q10077), TRX1_ORYSJ  (Q6K431)

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PDB
[Detailed view]

78 PDB

1FAQ; 1FAR; 1KBE; 1KBF; 1PTQ; 1PTR; 1R79; 1RFH; 1TBN; 1TBO; 1XA6; 1Y8F; 2DB6; 2E73; 2ELI; 2ENN; 2ENZ; 2FNF; 2VRW; 2YUU; 3BJI; 3CXL; 3KY9; 3PFQ; 3UEJ; 3UEY; 3UFF; 3UGD; 3UGI; 3UGL; 4B6D; 4FKD; 4L9M; 5UE8; 6NEW; 6NF1; 6NFA; 6NYB; 6PTS; 6PTW; 6Q0J; 6Q0K; 6Q0T; 6RA0; 6UAN; 6XGU; 6XGV; 6XHA; 6XHB; 6XI7; 7JHP; 7KND; 7KNJ; 7KO6; 7L92; 7LCB; 7LEO; 7LF3; 7MFD; 7MFE; 7MFF; 7T7C; 7T7R; 7T7V; 7T7X; 7T81; 7Z37; 7Z38; 7Z6E; 7ZR0; 7ZR5; 7ZR6; 8CHF; 8CPD; 8DGS; 8DGT; 8T75; 8U1L
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