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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS00503


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PURL: https://purl.expasy.org/prosite/signature/PS00503

Direct ScanProsite submission
General information about the entry

Entry name [info] PECTINESTERASE_2
Accession [info] PS00503
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED;
01-JUN-2002 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00413
Associated ProRule [info] PRU10040

Name and characterization of the entry

Description [info] Pectinesterase signature 2.
Pattern [info]
[IV]-x-G-[STAD]-[LIVT]-D-[FYI]-[IV]-[FSN]-G.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 148 in 148 different sequences
Number of true positive hits 85 in 85 different sequences
Number of 'unknown' hits 0
Number of false positive hits 63 in 63 different sequences
Number of false negative sequences 17
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 57.43 %
Recall (true positives / (true positives + false negatives)) 83.33 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 6
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
85 sequences

AL11A_OLEEU (D8VPP5), AL11B_OLEEU (B2VPR8), PME12_ARATH (O48711), 
PME13_ARATH (Q7Y201), PME14_ARATH (Q9ZQA4), PME15_ARATH (Q9ZQA3), 
PME16_ARATH (Q9SKX2), PME17_ARATH (O22149), PME18_ARATH (Q1JPL7), 
PME1_ARATH  (Q43867), PME1_CITSI  (O04886), PME1_FICPW  (P83947), 
PME1_SOLLC  (P14280), PME20_ARATH (O22256), PME21_SOLLC (P09607), 
PME22_ARATH (Q9M9W7), PME22_SOLLC (Q96575), PME23_ARATH (Q8GXA1), 
PME24_ARATH (Q9SG77), PME25_ARATH (Q94CB1), PME26_ARATH (Q9LUL8), 
PME29_ARATH (Q4PSN0), PME2_ARATH  (Q42534), PME2_CITSI  (O04887), 
PME31_ARATH (Q9LVQ0), PME32_ARATH (Q9LXK7), PME33_ARATH (Q9STY3), 
PME34_ARATH (Q9M3B0), PME35_ARATH (Q9LYT5), PME36_ARATH (Q84R10), 
PME37_ARATH (Q5MFV6), PME38_ARATH (O81320), PME39_ARATH (O81415), 
PME3_ARATH  (O49006), PME3_CITSI  (P83948), PME3_PHAVU  (Q43111), 
PME3_SOLLC  (Q96576), PME40_ARATH (O81301), PME41_ARATH (Q8RXK7), 
PME43_ARATH (O23447), PME44_ARATH (Q9SMY7), PME45_ARATH (Q9SMY6), 
PME46_ARATH (Q9FF78), PME47_ARATH (Q9FF77), PME4_ARATH  (O80722), 
PME52_ARATH (O04953), PME53_ARATH (Q8VYZ3), PME54_ARATH (Q3E989), 
PME56_ARATH (Q4PT34), PME58_ARATH (Q9FJ21), PME59_ARATH (Q9FHN5), 
PME5_ARATH  (Q5MFV8), PME60_ARATH (Q9FHN4), PME61_ARATH (Q9FK05), 
PME67_ARATH (Q9LSP1), PME68_ARATH (Q8LPF3), PME6_ARATH  (O49298), 
PME7_ARATH  (Q9SRX4), PME8_ARATH  (O23038), PMEA_ASPFC  (B0Y9F9), 
PMEA_ASPFN  (B8NPS7), PMEA_ASPFU  (Q4WBT5), PMEA_ASPNC  (A2QK82), 
PMEA_ASPOR  (Q2UBD9), PMEA_DICCH  (P0C1A8), PMEA_DICD3  (P0C1A9), 
PMEA_EMENI  (Q5B7U0), PMEA_NEOFI  (A1DBT4), PMEB_DICD3  (Q47474), 
PMEB_PECPM  (P55743), PMEU1_SOLLC (Q43143), PME_ACTDE   (P85076), 
PME_ASPAC   (Q12535), PME_ASPNG   (P17872), PME_BRACM   (Q42608), 
PME_BRANA   (P41510), PME_DAUCA   (P83218), PME_MEDSA   (Q42920), 
PME_PARHY   (C0HMB4), PME_PETIN   (Q43043), PME_PRUPE   (Q43062), 
PME_RALN1   (P58601), PME_RALSL   (P24791), PME_SITOR   (E7CIP7), 
YBHC_ECOLI  (P46130)
» more

UniProtKB/Swiss-Prot
False negative sequences
17 sequences

PME10_ARATH (O64479), PME11_ARATH (Q9SIJ9), PME21_ARATH (Q8GX86), 
PME28_ARATH (Q3E8Z8), PME30_ARATH (Q3EAY9), PME42_ARATH (Q1PEC0), 
PME48_ARATH (Q9LY19), PME49_ARATH (Q9LY18), PME50_ARATH (Q9LY17), 
PME51_ARATH (Q9LXD9), PME55_ARATH (Q3E9D3), PME57_ARATH (Q9MAL0), 
PME62_ARATH (Q9FM79), PME63_ARATH (Q9FKF3), PME64_ARATH (Q8L7Q7), 
PME66_ARATH (Q4PSQ5), PPME1_ARATH (Q84WM7)
» more

UniProtKB/Swiss-Prot
'Partial' sequences
2 sequences

PME_CAPAA   (P86075), PME_CAPCH   (P86085)

		
UniProtKB/Swiss-Prot
False positive sequences
63 sequences

NUOD1_BEII9 (B2IHW4), NUOD1_NITHX (Q1QP34), NUOD1_RHIE6 (B3PW00), 
NUOD1_RHIEC (Q2K9T1), NUOD1_RHIME (P56907), NUOD1_SINMW (A6U7W6), 
NUOD2_BEII9 (B2ILG7), NUOD2_NITHX (Q1QL87), NUOD_ACICJ  (A5FX11), 
NUOD_AFIC5  (B6JGW3), NUOD_AGRFC  (A9CJA9), NUOD_ALBFT  (Q21YC4), 
NUOD_ANAMM  (Q5PAR3), NUOD_ANAPZ  (Q2GJY9), NUOD_AZOC5  (A8I3Z3), 
NUOD_BARBK  (A1USX0), NUOD_BARHE  (Q6G391), NUOD_BARQU  (Q6FZY8), 
NUOD_BART1  (A9IUP7), NUOD_BRADU  (Q89KI9), NUOD_BRASB  (A5EK97), 
NUOD_BRASO  (A4YVK9), NUOD_BRUA1  (B2S546), NUOD_BRUA2  (Q2YNG0), 
NUOD_BRUA4  (A6X1N0), NUOD_BRUAB  (Q57DU8), NUOD_BRUC2  (A9MAI2), 
NUOD_BRUME  (Q8YGK3), NUOD_BRUO2  (A5VPY6), NUOD_BRUSI  (B0CLD2), 
NUOD_BRUSU  (Q8G1B4), NUOD_CAUSK  (B0SZ49), NUOD_CAUVC  (Q9A6X4), 
NUOD_CHESB  (Q11JK3), NUOD_EHRCJ  (Q3YS37), NUOD_EHRCR  (Q2GGK7), 
NUOD_EHRRG  (Q5FGV3), NUOD_EHRRW  (Q5HB88), NUOD_HYPNA  (Q0C1E4), 
NUOD_JANSC  (Q28T72), NUOD_MAGMM  (A0LDS4), NUOD_METEP  (A9W1N0), 
NUOD_METPB  (B1ZA43), NUOD_METRJ  (B1LUN4), NUOD_METS4  (B0ULK7), 
NUOD_NEOSM  (Q2GDJ8), NUOD_NITWN  (Q3SRE6), NUOD_PARL1  (A7HY46), 
NUOD_PELUB  (Q4FM88), NUOD_PHEZH  (B4RCM6), NUOD_RHIJ3  (Q1MIL2), 
NUOD_RHILO  (Q98KQ8), NUOD_RHILW  (B5ZYL5), NUOD_RHOP2  (Q2IWY2), 
NUOD_RHOP5  (Q07NM3), NUOD_RHOPA  (Q6N5M5), NUOD_RHOPB  (Q215I0), 
NUOD_RHOPS  (Q135X7), NUOD_RHOPT  (B3Q7N3), NUOD_WOLPM  (Q73HJ8), 
NUOD_WOLPP  (B3CLH1), NUOD_WOLTR  (Q5GTF8), NUOD_XANP2  (A7IPA4)
» more

PDB
[Detailed view]
12 PDB

pdb_00001gq8; pdb_00001qjv; pdb_00001xg2; pdb_00002nsp; pdb_00002nst; pdb_00002nt6; pdb_00002nt9; pdb_00002ntb; pdb_00002ntp; pdb_00002ntq; pdb_00003grh; pdb_00004pmh