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PROSITE entry PS00622


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General information about the entry

Entry name [info] HTH_LUXR_1
Accession [info] PS00622
Entry type [info] PATTERN
Date [info] 01-JUN-1992 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00542

Name and characterization of the entry

Description [info] LuxR-type HTH domain signature.
Pattern [info] 
[GDC]-x(2)-[NSTAVY]-x(2)-[IV]-[GSTA]-x(2)-[LIVMFYWCT]-x-[LIVMFYWCR]-x(3)-
[NST]-[LIVM]-x(2)-{T}-x(2)-[NRHSA]-[LIVMSTA]-x(2)-[KR].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_04 which contains 571'864 sequence entries.


Total number of hits 189 in 189 different sequences
Number of true positive hits 174 in 174 different sequences
Number of 'unknown' hits 0
Number of false positive hits 15 in 15 different sequences
Number of false negative sequences 77
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 92.06 %
Recall (true positives / (true positives + false negatives)) 69.32 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 174 sequences 

AGMR_PSEAE  (P29369), AGMR_PSEPU  (A8R3T0), ANOR_ACINO  (A0A0N8YGA2), 

BVGA_BORBR  (P0A4H3), BVGA_BORPA  (P0A4H4), BVGA_BORPE  (P0A4H2), 
CARR_PECCC  (Q46751), CMPA_BACSU  (P14204), CSGD_ECOLI  (P52106), 
CSGD_SALTY  (O54294), DCTR_RHOCA  (P37740), DEGU_BACSU  (P13800), 
DEGU_BREBE  (P54662), DEVR_MYCTO  (P9WMF8), DEVR_MYCTU  (P9WMF9), 
ECHR_DICCH  (Q46967), ECNR_CITFR  (O69280), ESAR_PANSE  (P54293), 
EVGA_ECO57  (P0ACZ6), EVGA_ECOL6  (P0ACZ5), EVGA_ECOLI  (P0ACZ4), 
EVGA_SHIFL  (P0ACZ7), EXPR_DICD3  (Q47188), EXPR_PECPM  (Q47189), 
FIMZ_ECO57  (P0AEL9), FIMZ_ECOLI  (P0AEL8), FIMZ_SALTY  (P26319), 
FIXJ_AZOC5  (P26487), FIXJ_BRADU  (P23221), FIXJ_RHIME  (P10958), 
GACA_PSEAE  (Q51373), GACA_PSEPH  (P32967), GACA_PSEU2  (Q52376), 
GACA_PSEVI  (P95582), GERE_BACSU  (P11470), LASR_PSEAE  (P25084), 
LIAR_BACSU  (O32197), LNRK_BACSU  (P94439), LUXR_ALIFS  (P12746), 
LUXS_ALIF1  (P35327), MALT_CITK8  (A8AQX2), MALT_CROS8  (A7ME76), 
MALT_ECO24  (A7ZSU8), MALT_ECO27  (B7UKC3), MALT_ECO45  (B7MDP4), 
MALT_ECO55  (B7L4U8), MALT_ECO57  (Q8X701), MALT_ECO5E  (B5YTW9), 
MALT_ECO7I  (B7NMI3), MALT_ECO81  (B7N1J6), MALT_ECO8A  (B7M2H9), 
MALT_ECOBW  (C4ZVX0), MALT_ECODH  (B1X764), MALT_ECOHS  (A8A5M7), 
MALT_ECOK1  (A1AGU2), MALT_ECOL5  (Q0TC49), MALT_ECOL6  (Q8CXX5), 
MALT_ECOLC  (B1IP47), MALT_ECOLI  (P06993), MALT_ECOLU  (B7NE23), 
MALT_ECOSE  (B6I2Y2), MALT_ECOSM  (B1LI79), MALT_ECOUT  (Q1R5L6), 
MALT_ENT38  (A4WFK6), MALT_ESCF3  (B7LSC1), MALT_KLEP3  (B5XTR7), 
MALT_KLEP7  (A6TF41), MALT_PHOLL  (Q7N976), MALT_SALA4  (B5F8N2), 
MALT_SALAR  (A9MMA9), MALT_SALCH  (Q57IV9), MALT_SALDC  (B5FKD6), 
MALT_SALEP  (B5R375), MALT_SALG2  (B5R7J9), MALT_SALHS  (B4TKU2), 
MALT_SALNS  (B4SVL9), MALT_SALPA  (Q5PM00), MALT_SALPB  (A9MTT7), 
MALT_SALPK  (B5BHH3), MALT_SALSV  (B4TY75), MALT_SALTI  (Q8Z227), 
MALT_SALTY  (Q8ZLI3), MALT_SERP5  (A8GKU0), MALT_SHIBS  (Q31VL4), 
MALT_SHIF8  (Q0SZP7), MALT_SHISS  (Q3YWK7), MALT_VIBC1  (A7N5N6), 
MALT_VIBCH  (Q9KNF3), MALT_VIBPA  (Q87FQ5), MALT_VIBVU  (Q8D4P3), 
MALT_VIBVY  (Q7MG94), MALT_YERE8  (A1JSF2), MALT_YERP3  (A7FNW4), 
MALT_YERPA  (Q1C2L4), MALT_YERPB  (B2K5W2), MALT_YERPE  (Q8ZJI2), 
MALT_YERPP  (A4TGR4), MALT_YERPS  (Q664J3), MALT_YERPY  (B1JHZ0), 
MOAR_KLEAE  (P54794), NARL_ECO57  (P0AF30), NARL_ECOL6  (P0AF29), 
NARL_ECOLI  (P0AF28), NARL_SHIFL  (P0AF31), NARP_ECOLI  (P31802), 
NARP_HAEIN  (P44845), NODW_BRADU  (P15940), NREC_STAA1  (A7X623), 
NREC_STAA2  (A6U4C0), NREC_STAA3  (Q2FEA6), NREC_STAA8  (Q2FVM7), 
NREC_STAA9  (A5IVH2), NREC_STAAB  (Q2YZ42), NREC_STAAC  (Q5HDG5), 
NREC_STAAE  (A6QJN1), NREC_STAAM  (Q99RN8), NREC_STAAN  (Q7A3U5), 
NREC_STAAR  (Q6GE42), NREC_STAAS  (Q6G6T0), NREC_STAAT  (A8Z580), 
NREC_STAAW  (Q7A029), NREC_STACT  (Q7WZY4), NREC_STAEQ  (Q5HLK6), 
NREC_STAES  (Q8CN75), NREC_STAHJ  (Q4L8Q6), PHZR_PSECL  (P54303), 
PHZR_PSEFL  (Q51786), RCSA_ECO57  (P69406), RCSA_ECOLI  (P0DMC9), 
RCSA_ECOLX  (P0DMD0), RCSA_ERWAM  (P20098), RCSA_KLEAE  (P05338), 
RCSA_PANSE  (P27488), RCSA_SALTI  (Q56083), RCSA_SALTY  (P54698), 
RCSB_ECO57  (P69409), RCSB_ECOL6  (P69408), RCSB_ECOLI  (P0DMC7), 
RCSB_ECOLX  (P0DMC8), RCSB_SALTI  (Q56127), RCSB_SALTY  (P58663), 
RCSB_SHIFL  (P69410), RHIR_RHILV  (Q03316), RHLR_PSEAE  (P54292), 
SDIA_ECOLI  (P07026), SGAR_HYPME  (P56644), SOLR_RALN1  (P58590), 
SOLR_RALSL  (O30919), SSRB_SALTY  (Q7CQM5), TDIR_THAAR  (O87940), 
THAA_BURTA  (Q2T4M4), TRPO_PSEAE  (P24908), TTRR_SALTY  (Q7CQM8), 
UHPA_ECO57  (P0AGA8), UHPA_ECOL6  (P0AGA7), UHPA_ECOLI  (P0AGA6), 
UHPA_SALTY  (P27667), UHPA_SHIFL  (P0AGA9), UVRY_ECO57  (P66798), 
UVRY_ECOL6  (P66797), UVRY_ECOLI  (P0AED5), UVRY_SHIFL  (P0AED6), 
Y4QH_SINFN  (P55629), Y890_MYCTO  (P9WMG0), Y890_MYCTU  (P9WMG1), 
Y914_MYCBO  (P59969), YDFI_BACSU  (P96686), YENR_YEREN  (P54295), 
YEXN_AERSA  (P45785), YGEK_ECO57  (P58664), YGEK_ECOLI  (Q46791), 
YHCZ_BACSU  (O07528), YHJB_ECOLI  (P37640), YXJL_BACSU  (P55184)
» more

UniProtKB/Swiss-Prot
False negative sequences		 77 sequences 

AHYR_AERHY  (P0A3J5), ALKS_ALCBS  (Q0VKZ4), ALKS_PSEOL  (P17051), 

ALKS_PSEPU  (Q9L4M7), ASAR_AERSA  (P0A3J6), BGLJ_ECOLI  (P39404), 
BJAR1_BRADU (Q89VI3), BRPA_STRHY  (Q01108), DCTR_ECO57  (Q8X5P3), 
DCTR_ECOL6  (Q8FCK2), DCTR_ECOLI  (P37195), DCTR_SHIFL  (Q83J60), 
DESR_BACSU  (O34723), ECPR_ECO24  (A7ZI28), ECPR_ECO27  (B7UJE2), 
ECPR_ECO55  (B7L425), ECPR_ECO57  (Q8X6I1), ECPR_ECO5E  (B5Z1N3), 
ECPR_ECO81  (B7MP71), ECPR_ECODH  (B1XE36), ECPR_ECOHS  (A7ZWT2), 
ECPR_ECOK1  (A1A7X7), ECPR_ECOKI  (Q9AME2), ECPR_ECOL5  (Q0TKZ0), 
ECPR_ECOL6  (Q8FKL2), ECPR_ECOLC  (B1J0X8), ECPR_ECOLI  (P71301), 
ECPR_ECOLU  (B7N8J2), ECPR_ECOSE  (B6I082), ECPR_ECOSM  (B1LHW0), 
ECPR_ECOUT  (Q1RFQ3), ECPR_KLEP3  (B5Y159), ECPR_KLEP7  (A6T571), 
ECPR_SHIBS  (Q325R5), EXAE_PSEPU  (A8R3S7), GADE_ECO57  (P63206), 
GADE_ECOL6  (P63205), GADE_ECOLI  (P63204), GADE_SHIFL  (P63207), 
MCTR_RHIJ3  (Q1M7A0), MOXX_PARDE  (P29904), NARL_MYCTO  (P9WGM4), 
NARL_MYCTU  (P9WGM5), RAIR_RHIET  (O54452), RPAR_RHOPA  (Q6NCZ5), 
TMOT_PSEME  (Q8KR08), TODT_PSEP1  (A5W4E2), TODT_PSEPT  (I7CA98), 
TODT_PSEPU  (Q3LWR6), TRAR_AGRFC  (P54294), TRAR_AGRVI  (P33909), 
TRAR_RHIRD  (P33905), TRAR_SINFN  (P55407), VANR_VIBAN  (P74946), 
VJBR_BRUA2  (Q2YJ50), VJBR_BRUAB  (Q579W9), VJBR_BRUME  (Q8YAY5), 
VJBR_BRUO2  (A5VTN1), VJBR_BRUSU  (Q8FXF9), VRAR_STAA1  (P0C0Z1), 
VRAR_STAAC  (Q5HEP0), VRAR_STAAM  (Q7A2Q1), VRAR_STAAN  (Q7A4R9), 
VRAR_STAAR  (Q6GFH3), VRAR_STAAS  (Q6G850), VRAR_STAAW  (Q7A0I0), 
VRAR_STAEQ  (Q5HN50), VRAR_STAES  (Q8CNP9), VRAR_STAHJ  (Q4L7J5), 
VRAR_STAS1  (Q49YS9), YCF29_CYAPA (P48359), YCF29_GUITH (O78417), 
YCF29_NEOYE (Q1XDE4), YCF29_PORPU (P51343), YJJQ_ECOLI  (P0ADD7), 
YUAB_ECOLI  (Q9JMT8), YUKR_YERRU  (O87971)
» more

UniProtKB/Swiss-Prot
False positive sequences		 15 sequences 

ANS1B_DANRE (A5PMU4), GLMU_STAA3  (Q2FJE2), GLMU_STAA8  (Q2G0S3), 

GLMU_STAAB  (Q2YVU6), GLMU_STAAC  (Q5HIH6), GLMU_STAAM  (Q99WA4), 
GLMU_STAAN  (Q7A7B4), GLMU_STAAR  (Q6GJH2), GLMU_STAAS  (Q6GBY9), 
GLMU_STAAW  (Q8NXZ7), K1549_HUMAN (Q9HCM3), K1549_MOUSE (Q68FD9), 
RPSH_BACLI  (P02964), RPSH_BACSU  (P17869), Y170_LACJO  (P60951)
» more

PDB
[Detailed view]		 39 PDB

1A04; 1FSE; 1JE8; 1RNL; 1X3U; 1ZG1; 1ZG5; 1ZLJ; 1ZLK; 2KRF; 3C3W; 3C57; 3ULQ; 4LFU; 4LGW; 5F64; 5O8Y; 5O8Z; 5VXN; 5W43; 6EO2; 6EO3; 6MWH; 6MWL; 6MWW; 6MWZ; 6V7W; 6V7X; 6ZIX; 6ZJ2; 7R3E; 7R3G; 7R3H; 7R3I; 7R3J; 8B4A; 8DQ0; 8DQ1; 8U3B
» more