PROSITE entry PS00727

View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission

General information about the entry

Entry name [info]	AP_NUCLEASE_F1_2
Accession [info]	PS00727
Entry type [info]	PATTERN
Date [info]	01-DEC-1992 CREATED; 01-DEC-2004 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00598

Name and characterization of the entry

Description [info]	AP endonucleases family 1 signature 2.
Pattern [info]	D-[ST]-[FY]-[RP]-[KHQ]-x(7,8)-[FYWD]-[ST]-[FYW](2).

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_05 which contains 572'214 sequence entries.

Total number of hits	19 in 19 different sequences
Number of true positive hits	19 in 19 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	11
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	63.33 %

Comments [info]

Taxonomic range [info]	Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

19 sequences

APEA_DICDI  (P51173), APEX1_BOVIN (P23196), APEX1_GORGO (A1YES6),

APEX1_HUMAN (P27695), APEX1_MOUSE (P28352), APEX1_PANPA (A1YFZ3), 
APEX1_PANTR (A2T6Y4), APEX1_PONPY (A2T7I6), APEX1_RAT   (P43138), 
APN2_SCHPO  (P87175), ARP_ARATH   (P45951), EX3_ECOLI   (P09030), 
EX3_HAEIN   (P44318), EX3_SALTI   (P0A1B0), EX3_SALTY   (P0A1A9), 
EXOA_BACSU  (P37454), EXOA_STRPN  (P0A2X3), EXOA_STRR6  (P0A2X4), 
RRP1_DROME  (P27864)

» more

Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

11 sequences

APE1L_ARATH (Q5XF07), APE2_ARATH  (F4JNY0), APEX1_DANRE (A0MTA1),

APEX2_BOVIN (Q5E9N9), APEX2_HUMAN (Q9UBZ4), APEX2_MOUSE (Q68G58), 
APEX2_XENLA (Q6DDT4), APEX_PLABA  (A0A509ADV9), APEX_PLAF7  (O97240), 
APN2_YEAST  (P38207), UREND_METTH (O26314)

» more

PDB
[Detailed view]

66 PDB

1AKO; 1BIX; 1DE8; 1DE9; 1DEW; 1E9N; 1HD7; 2ISI; 2O3H; 3U8U; 4IEM; 4LND; 4QH9; 4QHD; 4QHE; 5CFE; 5CFG; 5DFF; 5DFH; 5DFI; 5DFJ; 5DG0; 5WN0; 5WN1; 5WN2; 5WN4; 5WN5; 6BOQ; 6BOR; 6BOS; 6BOT; 6BOU; 6BOV; 6BOW; 6MK3; 6MKK; 6MKM; 6MKO; 6P93; 6P94; 6W0Q; 6W2P; 6W3L; 6W3N; 6W3Q; 6W3U; 6W43; 6W4I; 6W4T; 7CD5; 7CD6; 7LPG; 7LPH; 7LPI; 7LPJ; 7MCR; 7MEV; 7SUV; 7SVB; 7TC2; 7TC3; 7TR7; 7U50; 8KA3; 8KA4; 8KA5
» more