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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS00878


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PURL: https://purl.expasy.org/prosite/signature/PS00878

Direct ScanProsite submission
General information about the entry

Entry name [info] ODR_DC_2_1
Accession [info] PS00878
Entry type [info] PATTERN
Date [info] 01-OCT-1993 CREATED;
01-NOV-1997 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00685

Name and characterization of the entry

Description [info] Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site.
Pattern [info] 
[FY]-[PA]-x-K-[SACV]-[NHCLFW]-x(4)-[LIVMF]-[LIVMTA]-x(2)-[LIVMA]-x(3)-
[GTE].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 153 in 153 different sequences
Number of true positive hits 130 in 130 different sequences
Number of 'unknown' hits 0
Number of false positive hits 23 in 23 different sequences
Number of false negative sequences 61
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 84.97 %
Recall (true positives / (true positives + false negatives)) 68.06 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] pyridoxal_phosphate at position 4
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 130 sequences 

ADC1A_TOBAC (A0A1S3YCW2), ADC1B_TOBAC (A0A1S3WYR7), ADC2_ORYSJ  (Q7XRA1), 

AZIN2_HUMAN (Q96A70), AZIN2_XENLA (Q9I8S4), DCDA1_ARATH (Q949X7), 
DCDA2_ARATH (Q94A94), DCDA_AQUAE  (O67262), DCDA_ARCFU  (O29458), 
DCDA_BACMT  (P41023), DCDA_BACSU  (P23630), DCDA_BACTN  (Q8A800), 
DCDA_COREF  (Q8RQM6), DCDA_CORGL  (P09890), DCDA_ECOLI  (P00861), 
DCDA_ECOLW  (E0IWI3), DCDA_FRATH  (Q2A5D5), DCDA_HAEIN  (P44316), 
DCDA_HELPJ  (Q9ZME5), DCDA_HELPX  (B4XMC6), DCDA_HELPY  (P56129), 
DCDA_METJA  (Q58497), DCDA_METTH  (O27390), DCDA_MYCBO  (P0A5M5), 
DCDA_MYCLE  (Q50140), DCDA_MYCS2  (Q9X5M1), DCDA_MYCTO  (P9WIU6), 
DCDA_MYCTU  (P9WIU7), DCDA_ORYSJ  (Q6ZG77), DCDA_PSEAE  (P19572), 
DCDA_PSEFL  (O05321), DCDA_STRCO  (Q9ZBH5), DCDA_SYNY3  (Q55484), 
DCDA_THEMA  (Q9X1K5), DCDA_VIBCH  (Q9KVL7), DCLO_SELRU  (O50657), 
DCOR1_DROME (P40807), DCOR1_XENLA (P27120), DCOR2_DROME (P40808), 
DCOR_BOVIN  (P27117), DCOR_CAEEL  (P41931), DCOR_CANAL  (P78599), 
DCOR_CAPAN  (Q8S3N2), DCOR_CHICK  (P27118), DCOR_CRIGR  (P14019), 
DCOR_DATST  (P50134), DCOR_DICDI  (Q54UF3), DCOR_HUMAN  (P11926), 
DCOR_LEIDO  (P27116), DCOR_MOUSE  (P00860), DCOR_MUSPA  (P27119), 
DCOR_NEUCR  (P27121), DCOR_PANRE  (P49725), DCOR_RAT(P09057), 
DCOR_SCHPO  (Q9UQW9), DCOR_SOLLC  (O22616), DCOR_TRYBB  (P07805), 
DCOR_YEAST  (P08432), ODC1A_TOBAC (A0A1S4AUX8), ODC1B_TOBAC (P93351), 
ODC_NICGL   (E0WN94), ODC_NICGU   (Q9FPK5), SPE1_ARATH  (Q9SI64), 
SPE1_AVESA  (P22220), SPE1_BRAJU  (O82475), SPE1_DIACA  (Q96412), 
SPE1_ORYSJ  (Q9SNN0), SPE1_PEA(Q43075), SPE1_SOLLC  (P49726), 
SPE1_SOYBN  (Q39827), SPE2_ARATH  (O23141), SPE2_THECC  (O81160), 
SPEA1_SYNY3 (P74576), SPEA2_SYNY3 (P72587), SPEA_ALKEH  (Q0ACK8), 
SPEA_BACFN  (Q5LIQ3), SPEA_BACFR  (Q64ZT8), SPEA_BACTN  (Q8A2B1), 
SPEA_CITBB  (B5EIW4), SPEA_DEIRA  (Q9RXR4), SPEA_ECO57  (Q8XCX9), 
SPEA_ECO5E  (B5YQD6), SPEA_ECOL6  (Q8FE34), SPEA_ECOLI  (P21170), 
SPEA_ECOSM  (B1LDE8), SPEA_GEODF  (B9M6H6), SPEA_GEOMG  (Q39X78), 
SPEA_GEOSL  (A0A4W3), SPEA_GEOSM  (C6E3V4), SPEA_GEOUR  (A5GB52), 
SPEA_GLOVI  (Q7NE10), SPEA_HAMD5  (C4K6F4), SPEA_KLEP3  (B5XUB1), 
SPEA_MARN8  (A1TY02), SPEA_NEIMA  (Q9JT25), SPEA_NEIMB  (Q9K0U3), 
SPEA_NOSS1  (Q8YRP3), SPEA_PARMW  (Q7U3S0), SPEA_PASMU  (Q9CL60), 
SPEA_PELPD  (A1AS90), SPEA_PHOLL  (Q7N121), SPEA_PHOV8  (A6L012), 
SPEA_PROM0  (A3PA96), SPEA_PROM2  (A8G243), SPEA_PROM3  (A2CDK1), 
SPEA_PROM5  (A2BU00), SPEA_PROM9  (Q31DD8), SPEA_PROMA  (Q7VEG4), 
SPEA_PROMH  (B4F1A4), SPEA_PROMM  (Q7TUJ9), SPEA_PROMP  (Q7V3M9), 
SPEA_PROMS  (A2BNH3), SPEA_PSEAE  (Q9HUX1), SPEA_RHOBA  (Q7UTS2), 
SPEA_SALA4  (B5F5L1), SPEA_SALCH  (Q57K30), SPEA_SALDC  (B5FUJ7), 
SPEA_SALHS  (B4THH1), SPEA_SALNS  (B4T5J3), SPEA_SALPB  (A9N4N1), 
SPEA_SALSV  (B4TV55), SPEA_SALTI  (P60658), SPEA_SALTY  (P60659), 
SPEA_SHIF8  (Q0T0V3), SPEA_SHIFL  (Q83Q93), SPEA_SYNR3  (A5GWM2), 
SPEA_THEVB  (Q8DHY6), SPEA_TRIL1  (B3EAF3), SPEA_YERPE  (Q8ZHG8), 
TABA_PSEAJ  (P31851)
» more

UniProtKB/Swiss-Prot
False negative sequences		 61 sequences 

AZIN1_HUMAN (O14977), AZIN1_MOUSE (O35484), AZIN1_PONAB (Q5R7K3), 

AZIN1_RAT   (Q63764), AZIN2_MOUSE (Q8BVM4), BTRK_NIACI  (Q2L4H3), 
CAPDC_SYNY3 (P73562), DCDA_ACTPA  (O69203), DCDA_BUCAI  (P57513), 
DCDA_BUCAP  (Q8K9C4), DCDA_BUCBP  (Q89AC6), DCDA_CAMJE  (Q9PII5), 
DCDA_DEIRA  (Q9RTK2), DCDA_HALH5  (Q9KCM5), DCDA_NEIMA  (Q9JWA6), 
DCDA_NEIMB  (Q9JXM2), DCDA_THEAC  (Q9HK20), DCDA_ZYMMO  (Q9Z661), 
DOKDC_SALTY (Q8ZNC4), NSPC_CAMJ8  (A8FNH9), NSPC_HERAR  (Q5QCP2), 
NSPC_VIBAL  (Q56575), NSPC_VIBCH  (Q9KRL4), NSPC_VIBCO  (C6YCI2), 
NSPC_VIBVU  (Q8D8D2), SBNH_STAA8  (Q2G1M6), SPEA_AERHH  (A0KIP8), 
SPEA_AERS4  (A4SPD6), SPEA_CHRVO  (Q7NU27), SPEA_PSEPK  (Q88QC7), 
SPEA_PSESM  (Q87VU3), SPEA_SHEAM  (A1S712), SPEA_SHEB2  (B8EAI2), 
SPEA_SHEB5  (A3D3G2), SPEA_SHEB8  (A6WM65), SPEA_SHEB9  (A9KY70), 
SPEA_SHEDO  (Q12LW6), SPEA_SHEFN  (Q083L6), SPEA_SHEHH  (B0TQX3), 
SPEA_SHELP  (A3QDD8), SPEA_SHEON  (Q8EFU5), SPEA_SHEPA  (A8H5G3), 
SPEA_SHEPC  (A4Y5Y9), SPEA_SHEPW  (B8CR70), SPEA_SHESA  (A0KVN8), 
SPEA_SHESH  (A8FWJ3), SPEA_SHESM  (Q0HJY2), SPEA_SHESR  (Q0HW78), 
SPEA_SHESW  (A1RKK8), SPEA_SHEWM  (B1KRD4), SPEA_TOLAT  (C4L9A9), 
SPEA_VIBCH  (Q9KLD1), SPEA_VIBPA  (Q87JS8), SPEA_VIBVU  (Q8DA54), 
SPEA_VIBVY  (Q7MK24), SPEA_XANAC  (Q8PFQ5), SPEA_XANCP  (Q8P448), 
SPEA_XYLF2  (B2I6M1), SPEA_XYLFA  (Q9PH02), SPEA_XYLFM  (B0U1H6), 
SPEA_XYLFT  (Q87F25)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

DCOR_PARBR  (Q92445)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			23 sequences
			


			
AR280_ARTOA (G1XU01), ASB2_BOVIN  (Q3SX45), ASB2_HUMAN  (Q96Q27), 

			
ASB2_MOUSE  (Q8K0L0), ASB2_RAT(Q5U2S6), CLAH1_ARATH (Q0WNJ6), 
CLAH2_ARATH (Q0WLB5), CMOA_SULDN  (Q30T90), KS6A4_HUMAN (O75676), 
KS6A4_MOUSE (Q9Z2B9), KS6A5_CHICK (Q5F3L1), KS6A5_HUMAN (O75582), 
KS6A5_MOUSE (Q8C050), KS6A5_PONAB (Q5R4K3), MGLA_VIBCH  (Q9KSD1), 
PHS1_SOLLC  (C1K5M3), POLN_CRPVC  (Q9IJX4), RPB1_FRG3G  (Q6GZW7), 
SCN8A_HUMAN (Q9UQD0), SCN8A_MOUSE (Q9WTU3), SCN8A_RAT   (O88420), 
SYY_STRMU   (Q8DS44), TBAL3_MOUSE (Q3UX10)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			34 PDB
			


			pdb_00001d7k; pdb_00001f3t; pdb_00001hkv; pdb_00001hkw; pdb_00001knw; pdb_00001ko0; pdb_00001qu4; pdb_00001szr; pdb_00001tuf; pdb_00001twi; pdb_00002o0t; pdb_00002on3; 
			
				pdb_00002oo0; pdb_00002p3e; pdb_00002qgh; pdb_00002yxx; pdb_00003c5q; pdb_00003n2b; pdb_00003nzq; pdb_00004zgy; pdb_00005bwa; pdb_00005gjm; pdb_00005gjn; pdb_00005gjo; 
				pdb_00005gjp; pdb_00005x7m; pdb_00005x7n; pdb_00006n2a; pdb_00006n2f; pdb_00007odc; pdb_00007s3f; pdb_00007s3g; pdb_00009b8m; pdb_00009b8n
			
			

			» more