PROSITE entry PS00973
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General information about the entry
| Entry name [info] | USP_2 |
| Accession [info] | PS00973 |
| Entry type [info] | PATTERN |
| Date [info] |
01-JUN-1994 CREATED;
01-DEC-2013 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00750 |
| Associated ProRule [info] | PRU10093 |
Name and characterization of the entry
| Description [info] | Ubiquitin specific protease (USP) domain signature 2. |
| Pattern [info] |
[YMF]-x-[LK]-x-[SAGNC]-[LIVMFT]-x(2)-H-x-G-x(4,6)-G-H-[YF]. |
Numerical results [info]
| Total number of hits | 297 in 297 different sequences |
| Number of true positive hits | 297 in 297 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 28 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 91.38 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes, Eukaryotic viruses |
| Maximum number of repetitions [info] | 1 |
| Site [info] | active_site at position 13 |
| Version [info] | 2 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
297 sequences
CREB_ASPCL (A1CIL1), CREB_ASPFC (B0Y4P5), CREB_ASPFN (B8NSV5), CREB_ASPFU (Q4WQI1), CREB_ASPNC (A2Q9N1), CREB_ASPOR (Q2UUG8), CREB_ASPTN (Q0CT11), CREB_EMENI (Q96V54), CREB_NEOFI (A1CW53), FAF_DROME (P55824), NOT_DROME (Q9VVR1), PUF_DROME (Q9VC56), U17L1_HUMAN (Q7RTZ2), U17L2_HUMAN (Q6R6M4), U17L3_HUMAN (A6NCW0), U17L5_HUMAN (A8MUK1), U17L6_HUMAN (Q6QN14), U17L7_HUMAN (P0C7H9), U17LA_HUMAN (C9JJH3), U17LB_HUMAN (C9JVI0), U17LC_MOUSE (G5E8I7), U17LD_HUMAN (C9JLJ4), U17LF_HUMAN (C9J2P7), U17LH_HUMAN (D6RBQ6), U17LI_HUMAN (D6R9N7), U17LJ_HUMAN (D6RCP7), U17LK_HUMAN (D6RJB6), U17LL_HUMAN (D6R901), U17LM_HUMAN (D6RA61), U17LO_HUMAN (Q0WX57), U17PA_MOUSE (Q61068), U17PB_MOUSE (E9Q9U0), U17PD_MOUSE (G5E8G2), U17PE_MOUSE (Q7M764), UB10A_XENLA (Q2NL57), UB10B_XENLA (Q7ZXR7), UB12A_XENLA (Q52KZ6), UB12B_XENLA (Q5M981), UB22A_XENLA (Q6GNI6), UB22B_XENLA (Q6DCJ1), UBP10_ARATH (Q9ZSB5), UBP10_BOVIN (A5PJS6), UBP10_HUMAN (Q14694), UBP10_MOUSE (P52479), UBP10_RAT (Q3KR59), UBP10_XENTR (Q6DIJ4), UBP10_YEAST (P53874), UBP11_ARATH (Q9MAQ3), UBP11_CANLF (Q01988), UBP11_HUMAN (P51784), UBP11_MOUSE (Q99K46), UBP11_RAT (Q5D006), UBP11_SCHPO (Q9UUD6), UBP11_YEAST (P36026), UBP12_ARATH (Q9FPT1), UBP12_BOVIN (A5D9H7), UBP12_DANRE (A4FUN7), UBP12_HUMAN (O75317), UBP12_MOUSE (Q9D9M2), UBP12_SALSA (C0HB46), UBP12_SCHPO (O60079), UBP12_YEAST (P39538), UBP13_ARATH (Q84WU2), UBP13_BOVIN (E1BMF7), UBP13_CHICK (E1BY77), UBP13_DANRE (F1QFS9), UBP13_HUMAN (Q92995), UBP13_MOUSE (Q5BKP2), UBP13_XENTR (F6V6I0), UBP13_YEAST (P38187), UBP14_ARATH (Q8L6Y1), UBP14_BOVIN (Q0IIF7), UBP14_CAEEL (Q17361), UBP14_HUMAN (P54578), UBP14_MOUSE (Q9JMA1), UBP14_PANTR (P60051), UBP14_RABIT (P40826), UBP14_SCHPO (Q11119), UBP14_YEAST (P38237), UBP15_BOVIN (Q2HJE4), UBP15_HUMAN (Q9Y4E8), UBP15_MOUSE (Q8R5H1), UBP15_RAT (Q9R085), UBP15_XENTR (F6Z5C0), UBP15_YEAST (P50101), UBP16_BOVIN (Q08DA3), UBP16_DANRE (A8HAL1), UBP16_EMENI (P0CAQ1), UBP16_HUMAN (Q9Y5T5), UBP16_MACFA (Q4R6X7), UBP16_MOUSE (Q99LG0), UBP16_RAT (Q2KJ09), UBP16_SCHPO (O74442), UBP16_XENLA (Q6PAW2), UBP16_XENTR (Q0VA64), UBP16_YEAST (Q02863), UBP18_HUMAN (Q9UMW8), UBP18_MOUSE (Q9WTV6), UBP18_PONAB (Q5RE63), UBP19_HUMAN (O94966), UBP19_MOUSE (Q3UJD6), UBP19_RAT (Q6J1Y9), UBP1_ARATH (Q9FPT5), UBP1_BOVIN (Q29RP1), UBP1_HUMAN (O94782), UBP1_MOUSE (Q8BJQ2), UBP1_RAT(Q569C3), UBP1_SCHPO (Q9USM5), UBP1_YEAST (P25037), UBP20_ARATH (Q9FPS7), UBP20_BOVIN (A7Z056), UBP20_DANRE (A5PN09), UBP20_HUMAN (Q9Y2K6), UBP20_MOUSE (Q8C6M1), UBP20_PONAB (Q5R5Z6), UBP20_XENLA (B1WBD7), UBP20_XENTR (A0JM59), UBP21_ARATH (Q9FIQ1), UBP21_BOVIN (Q2KJ72), UBP21_HUMAN (Q9UK80), UBP21_MOUSE (Q9QZL6), UBP21_RAT (B2GUX4), UBP22_BOVIN (P0C8Z3), UBP22_DANRE (A6H8I0), UBP22_HUMAN (Q9UPT9), UBP22_MOUSE (Q5DU02), UBP23_ARATH (Q9FPS4), UBP24_ARATH (Q9FPS3), UBP24_HUMAN (Q9UPU5), UBP24_MOUSE (B1AY13), UBP25_ARATH (Q9FPS2), UBP25_HUMAN (Q9UHP3), UBP25_MOUSE (P57080), UBP26_ARATH (Q9SCJ9), UBP26_HUMAN (Q9BXU7), UBP26_MOUSE (Q99MX1), UBP26_ORYSI (A2XDG4), UBP26_ORYSJ (A3AF13), UBP27_HUMAN (A6NNY8), UBP27_MOUSE (Q8CEG8), UBP28_CHICK (Q5ZID5), UBP28_HUMAN (Q96RU2), UBP28_MOUSE (Q5I043), UBP28_RAT (D3ZJ96), UBP29_HUMAN (Q9HBJ7), UBP29_MOUSE (Q9ES63), UBP2_ARATH (Q8W4N3), UBP2_BOVIN (Q2KHV7), UBP2_CHICK (O57429), UBP2_DROME (Q8IQ27), UBP2_HUMAN (O75604), UBP2_KLULA (O42726), UBP2_MOUSE (O88623), UBP2_RAT(Q5U349), UBP2_SCHPO (Q9P3U0), UBP2_YEAST (Q01476), UBP30_DANRE (A2BGT0), UBP30_DROME (Q9W462), UBP30_HUMAN (Q70CQ3), UBP30_MOUSE (Q3UN04), UBP30_RAT (D3ZPG5), UBP30_XENTR (A4QNN3), UBP31_HUMAN (Q70CQ4), UBP32_DROME (M9PD06), UBP32_HUMAN (Q8NFA0), UBP32_MOUSE (F8VPZ3), UBP33_BOVIN (A6QNM7), UBP33_DANRE (A5PMR2), UBP33_HUMAN (Q8TEY7), UBP33_MOUSE (Q8R5K2), UBP33_PONAB (Q5REG5), UBP33_XENTR (Q28CN3), UBP34_HUMAN (Q70CQ2), UBP34_MOUSE (Q6ZQ93), UBP35_HUMAN (Q9P2H5), UBP36_DROAN (B3M3M6), UBP36_DROER (B3NC86), UBP36_DROGR (B4IXE0), UBP36_DROME (Q9VRP5), UBP36_DROMO (B4KXJ5), UBP36_DROPS (Q2LZB1), UBP36_DROSE (B4HUI5), UBP36_DROSI (B4QIS3), UBP36_DROVI (B4LG38), UBP36_DROWI (B4MLR8), UBP36_DROYA (B4PIW8), UBP36_HUMAN (Q9P275), UBP36_MOUSE (B1AQJ2), UBP37_BOVIN (F1N5V1), UBP37_CANLF (E2RK09), UBP37_CHICK (E1C213), UBP37_DANRE (E7F6T8), UBP37_HUMAN (Q86T82), UBP37_MOUSE (Q8C0R0), UBP37_PIG (F1SRY5), UBP38_HUMAN (Q8NB14), UBP38_MOUSE (Q8BW70), UBP3_ARATH (O24454), UBP3_HUMAN (Q9Y6I4), UBP3_MOUSE (Q91W36), UBP3_SCHPO (O94269), UBP3_YEAST (Q01477), UBP40_HUMAN (Q9NVE5), UBP40_MOUSE (Q8BWR4), UBP42_BOVIN (E1B9W9), UBP42_HUMAN (Q9H9J4), UBP42_MOUSE (B2RQC2), UBP42_RAT (D3ZU96), UBP43_HUMAN (Q70EL4), UBP43_MOUSE (Q8BUM9), UBP44_AILME (D2HBJ8), UBP44_DANRE (Q7ZUM8), UBP44_HUMAN (Q9H0E7), UBP44_MOUSE (Q8C2S0), UBP44_XENTR (Q0V9G5), UBP45_DANRE (E9QG68), UBP45_HUMAN (Q70EL2), UBP45_MOUSE (Q8K387), UBP46_CAEEL (P34547), UBP46_DANRE (A5WWB0), UBP46_HUMAN (P62068), UBP46_MOUSE (P62069), UBP46_PONAB (Q5RBQ4), UBP46_RAT (F1M625), UBP47_CHICK (E1C1R4), UBP47_HUMAN (Q96K76), UBP47_MOUSE (Q8BY87), UBP47_XENLA (Q5U252), UBP47_XENTR (A1A5G2), UBP48_CAEEL (G5ECC7), UBP48_CHICK (Q5ZM45), UBP48_DANRE (A0A0R4IB93), UBP48_HUMAN (Q86UV5), UBP48_MOUSE (Q3V0C5), UBP48_RAT (Q76LT8), UBP49_HUMAN (Q70CQ1), UBP49_MOUSE (Q6P9L4), UBP4_ARATH (Q8LAM0), UBP4_BOVIN (A6QR55), UBP4_EREGS (Q754R5), UBP4_HUMAN (Q13107), UBP4_KLULA (Q9HFS7), UBP4_MOUSE (P35123), UBP4_PONAB (Q5RCD3), UBP4_RAT(B2GUZ1), UBP4_SCHPO (O60139), UBP4_VANPO (A7TGY3), UBP4_YEAS1 (B3LGK1), UBP4_YEAS7 (A6ZY34), UBP4_YEAST (P32571), UBP50_HUMAN (Q70EL3), UBP50_MACFA (Q4R6D3), UBP50_MOUSE (Q6P8X6), UBP51_HUMAN (Q70EK9), UBP51_MOUSE (B1AY15), UBP5_ARATH (O22207), UBP5_HUMAN (P45974), UBP5_MOUSE (P56399), UBP5_PONAB (Q5R407), UBP5_YEAST (P39944), UBP64_DROME (Q9W4C3), UBP6_ARATH (Q949Y0), UBP6_HUMAN (P35125), UBP6_SCHPO (Q92353), UBP6_YEAST (P43593), UBP71_SCHPO (Q9UTT1), UBP72_SCHPO (Q09879), UBP7_ARATH (Q84WC6), UBP7_CAEBR (Q60MK8), UBP7_CAEEL (Q7JKC3), UBP7_CHICK (Q6U7I1), UBP7_DROME (Q9VYQ8), UBP7_HUMAN (Q93009), UBP7_MOUSE (Q6A4J8), UBP7_RAT(Q4VSI4), UBP7_SCHPO (Q9P7S5), UBP7_YEAST (P40453), UBP8_ARATH (Q9C585), UBP8_HUMAN (P40818), UBP8_MOUSE (Q80U87), UBP8_SCHPO (Q09738), UBP8_YEAST (P50102), UBP9_ARATH (Q93Y01), UBP9_SCHPO (Q9P7V9), UBP9_YEAST (P39967), UBPA_DICDI (P54201), UBPB_DICDI (O96612), UBPE_DROME (Q24574), UBPL1_MIMIV (Q5UQR3), UBPY_CAEEL (Q09931), UL17C_HUMAN (C9JPN9), UP44A_XENLA (Q6NTR6), UP44B_XENLA (Q5XGZ2), USP9X_HUMAN (Q93008), USP9X_MOUSE (P70398), USP9Y_HUMAN (O00507), USP9Y_MOUSE (F8VPU6)» more
|
| UniProtKB/Swiss-Prot False negative sequences |
28 sequences
CYLD_BOVIN (Q1RMU2), CYLD_HUMAN (Q9NQC7), CYLD_MOUSE (Q80TQ2), CYLD_PONAB (Q5RED8), CYLD_RAT(Q66H62), FLA_ORYSJ (Q2R4I5), U17L4_HUMAN (A6NCW7), U17L8_HUMAN (P0C7I0), UBP10_SCHPO (Q9USR2), UBP15_ARATH (Q9FPS9), UBP15_ORYSJ (Q0E2F9), UBP16_ARATH (Q9SB51), UBP17_ARATH (Q9FKP5), UBP18_ARATH (Q67XW5), UBP19_ARATH (Q9SJA1), UBP22_ARATH (Q9LEW0), UBP27_ARATH (Q9FPS0), UBP39_HUMAN (Q53GS9), UBP39_MOUSE (Q3TIX9), UBP39_PONAB (Q5R761), UBP54_HUMAN (Q70EL1), UBP54_MOUSE (Q8BL06), UBP54_RAT (Q6IE24), UBPH_CAEEL (Q8WT44), UBPL2_MIMIV (Q5UPW7), USPL1_DANRE (Q6DRC5), USPL1_HUMAN (Q5W0Q7), USPL1_MOUSE (Q3ULM6)» more |
| PDB [Detailed view] |
142 PDB
1NB8; 1NBF; 1VJV; 2AYN; 2AYO; 2F1Z; 2GFO; 2HD5; 2IBI; 2Y5B; 2Y6E; 3I3T; 3IHP; 3M99; 3MHH; 3MHS; 3MTN; 3N3K; 3NHE; 3V6C; 3V6E; 4FIP; 4FJC; 4FK5; 4M5W; 4M5X; 4WA6; 4ZUX; 5A5B; 5CHT; 5CHV; 5CVM; 5CVN; 5CVO; 5FWI; 5GJQ; 5J7T; 5JTJ; 5JTV; 5K16; 5K1A; 5K1B; 5K1C; 5KYB; 5KYC; 5KYD; 5KYE; 5KYF; 5L8H; 5L8W; 5MPC; 5N9R; 5N9T; 5NGE; 5NGF; 5O71; 5OHK; 5OHN; 5OHP; 5TXK; 5UQV; 5UQX; 5VS6; 5VSB; 5VSK; 5WCH; 5WHC; 5XU8; 5XVE; 6AQR; 6CPM; 6CRN; 6DGF; 6F5H; 6GH9; 6GHA; 6H4H; 6H4I; 6H4J; 6HEH; 6HEI; 6HEJ; 6HEK; 6HEL; 6IIK; 6IIL; 6IIM; 6IIN; 6JLQ; 6LVS; 6M1K; 6ML1; 6T9L; 6VN2; 6VN3; 6VN4; 6VN5; 6VN6; 7AY0; 7AY1; 7AY2; 7CM2; 7QO4; 7QO5; 7R2G; 7TUO; 7W37; 7W38; 7W39; 7W3A; 7W3B; 7W3C; 7W3F; 7W3G; 7W3H; 7W3I; 7W3J; 7W3K; 7W3M; 7W3R; 7W3U; 7XHH; 7XHK; 7YXX; 7YXY; 7ZH3; 7ZH4; 8A9J; 8A9K; 8BS3; 8BS9; 8D0A; 8D1T; 8D4Z; 8HJE; 8OYP; 8P14; 8P19; 8P1P; 8P1Q; 8WG5; 8XPN » more |