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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS01305


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PURL: https://purl.expasy.org/prosite/signature/PS01305

Direct ScanProsite submission
General information about the entry

Entry name [info] MOAA_NIFB_PQQE
Accession [info] PS01305
Entry type [info] PATTERN
Date [info] 01-JUL-1998 CREATED;
01-DEC-2001 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC01009

Name and characterization of the entry

Description [info] moaA / nifB / pqqE family signature.
Pattern [info] 
[LIV]-x(3)-C-[NDP]-[LIVMF]-[DNQRS]-C-x-[FYM]-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 308 in 308 different sequences
Number of true positive hits 294 in 294 different sequences
Number of 'unknown' hits 1
Number of false positive hits 13 in 13 different sequences
Number of false negative sequences 56
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 95.77 %
Recall (true positives / (true positives + false negatives)) 84.00 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] iron_sulfur(?) at position 3
Site [info] iron_sulfur(?) at position 7
Site [info] iron_sulfur(?) at position 10
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 294 sequences 

CMO_PYRFU   (Q51741), CNX2_ARATH  (Q39055), FIXZ_RHILE  (P07748), 

MOAA1_MYCBO (Q7TX84), MOAA1_MYCTO (P9WJS2), MOAA1_MYCTU (P9WJS3), 
MOAA1_PSEAE (Q9HXD6), MOAA2_MYCBO (P65385), MOAA2_MYCTO (P9WJS0), 
MOAA2_MYCTU (P9WJS1), MOAA2_PSEAE (Q9I3K7), MOAA3_MYCBO (P62588), 
MOAA3_MYCTO (P62589), MOAA_ACAM1  (B0CDZ6), MOAA_ACIC1  (A0LVG0), 
MOAA_ACTP2  (A3N054), MOAA_ACTP7  (B3GXC5), MOAA_ACTPJ  (B0BNX2), 
MOAA_ACTSZ  (A6VPY2), MOAA_AERHH  (A0KIL8), MOAA_AERPE  (Q9YEV3), 
MOAA_AGRFC  (Q8UER0), MOAA_ALIB4  (A8ERS0), MOAA_ALKMQ  (A6TVF9), 
MOAA_ALKOO  (A8MLW5), MOAA_AQUAE  (O67929), MOAA_ARCFU  (O28273), 
MOAA_BACAC  (C3LA56), MOAA_BACCN  (A7GU01), MOAA_BACLD  (Q65DY5), 
MOAA_BACSU  (P39757), MOAA_BACVZ  (A7Z9P0), MOAA_BRADU  (Q89NT2), 
MOAA_BREBN  (C0Z9B3), MOAA_BRUA1  (B2S5I1), MOAA_BRUA2  (Q2YNT7), 
MOAA_BRUAB  (Q57DG3), MOAA_BRUC2  (A9MAX5), MOAA_BRUMB  (C0RIT4), 
MOAA_BRUME  (Q8YGY6), MOAA_BRUO2  (A5VQC9), MOAA_BRUSI  (B0CLT0), 
MOAA_BRUSU  (Q8G0X4), MOAA_CAMC1  (A7ZB87), MOAA_CAMC5  (A7GWA5), 
MOAA_CAMFF  (A0RMJ2), MOAA_CAMJ8  (A8FJX0), MOAA_CAMJD  (A7H1N9), 
MOAA_CAMJE  (Q9PIW6), MOAA_CAMJJ  (A1VXP5), MOAA_CAMJR  (Q5HX04), 
MOAA_CAMLR  (B9KDV3), MOAA_CARHZ  (Q3ADX8), MOAA_CAUVC  (Q9AC48), 
MOAA_CHLTE  (P59038), MOAA_CLOAB  (Q97HL8), MOAA_CLOB1  (A7FUZ6), 
MOAA_CLOB6  (C3KXJ8), MOAA_CLOBH  (A5I365), MOAA_CLOBJ  (C1FPG7), 
MOAA_CLOBK  (B1IN35), MOAA_CLOBL  (A7GEQ5), MOAA_CLOBM  (B1KU20), 
MOAA_CLOP1  (Q0TPG6), MOAA_CLOPE  (Q9WX96), MOAA_CLOPS  (Q0SS32), 
MOAA_CORGB  (A4QDF8), MOAA_CORGL  (Q8NR60), MOAA_CROS5  (B1X0G3), 
MOAA_CROS8  (A7MJ10), MOAA_CYAP4  (B8HWW4), MOAA_DESRM  (A4J6S5), 
MOAA_DINSH  (A8LIR8), MOAA_ECO24  (A7ZJJ0), MOAA_ECO27  (B7ULX8), 
MOAA_ECO45  (B7MGN9), MOAA_ECO55  (B7LC63), MOAA_ECO57  (P65383), 
MOAA_ECO5E  (B5YRM0), MOAA_ECO7I  (B7NNL1), MOAA_ECO81  (B7MQN5), 
MOAA_ECO8A  (B7M753), MOAA_ECOBW  (C4ZXV3), MOAA_ECODH  (B1X7B1), 
MOAA_ECOHS  (A7ZY37), MOAA_ECOL6  (P65382), MOAA_ECOLI  (P30745), 
MOAA_ECOLU  (B7NA81), MOAA_ECOSE  (B6I7T6), MOAA_ECOSM  (B1LM72), 
MOAA_ECTM1  (A4XW05), MOAA_EDWI9  (C5B7H2), MOAA_ERYLH  (Q2NCE3), 
MOAA_ESCF3  (B7LJY1), MOAA_GEOSL  (Q747W9), MOAA_GLOVI  (Q7NCF5), 
MOAA_HAEDU  (Q7VLN1), MOAA_HAEI8  (Q4QJR9), MOAA_HAEIE  (A5UBK4), 
MOAA_HAEIG  (A5UFB4), MOAA_HAEIN  (P45311), MOAA_HALH5  (Q9K9W9), 
MOAA_HALS3  (B0R2L5), MOAA_HALSA  (Q9HST4), MOAA_HALWD  (Q18G49), 
MOAA_HELMI  (B0TI16), MOAA_HELP2  (B6JM01), MOAA_HELPH  (Q1CTA2), 
MOAA_HELPJ  (Q9ZL75), MOAA_HELPY  (P56414), MOAA_KLEP3  (B5XYW6), 
MOAA_KLEP7  (A6T6M5), MOAA_LACPL  (Q88WY1), MOAA_LIMF3  (B2GCN4), 
MOAA_LISIN  (Q92CY2), MOAA_LISMC  (C1L1W8), MOAA_LISMF  (Q721B9), 
MOAA_LISMO  (Q8Y870), MOAA_LISW6  (A0AHG0), MOAA_MAGMM  (A0L7R4), 
MOAA_MARN8  (A1U578), MOAA_MARSD  (C6C060), MOAA_META3  (A6UX30), 
MOAA_METAC  (Q8TUG2), MOAA_METJA  (Q58234), MOAA_METMA  (Q8PX29), 
MOAA_METS5  (A4YH62), MOAA_METTH  (O27593), MOAA_METTM  (Q50746), 
MOAA_MICAN  (B0JNC2), MOAA_MOOTA  (Q2RGL2), MOAA_MYCMM  (B2HFA4), 
MOAA_MYCS2  (A0R443), MOAA_MYCSJ  (A3Q648), MOAA_MYCSK  (A1ULP7), 
MOAA_MYCSS  (Q1B3F3), MOAA_MYCUA  (A0PKZ7), MOAA_NAUPA  (B9L851), 
MOAA_NITHX  (Q1QN98), MOAA_NITSB  (A6Q5D0), MOAA_NITWN  (Q3STB0), 
MOAA_NOSP7  (B2J1M7), MOAA_NOSS1  (Q8YQG6), MOAA_PAENI  (Q44118), 
MOAA_PARDP  (A1B4A2), MOAA_PASMU  (Q9CN21), MOAA_PECAS  (Q6D3C7), 
MOAA_PELTS  (A5CYZ0), MOAA_PEPAC  (Q93KD1), MOAA_PETMO  (A9BF51), 
MOAA_PHOLL  (Q7N6P6), MOAA_PICP2  (B1XLR4), MOAA_PSE14  (Q48HV8), 
MOAA_PSEE4  (Q1I6J5), MOAA_PSEP1  (A5VZZ2), MOAA_PSEPF  (Q3KAS8), 
MOAA_PSEPG  (B0KST1), MOAA_PSEPK  (Q88E69), MOAA_PSEPW  (B1JCW0), 
MOAA_PSESM  (Q882V6), MOAA_PSEU2  (Q4ZU05), MOAA_PYRAB  (Q9V2G2), 
MOAA_PYRFU  (Q8U4J5), MOAA_PYRHO  (O57854), MOAA_RALN1  (Q8Y0K4), 
MOAA_RHIE6  (B3PQ08), MOAA_RHIEC  (Q2K7L4), MOAA_RHILO  (Q98MK6), 
MOAA_RHILW  (B5ZRM8), MOAA_RHIME  (Q92PB4), MOAA_RHOBA  (Q7UT69), 
MOAA_RHOCA  (Q9X5W3), MOAA_RHOPA  (Q3V7S1), MOAA_RHOPS  (Q139F2), 
MOAA_RHOPT  (B3QCQ7), MOAA_RIPO1  (B7JWW6), MOAA_SACD2  (Q21I62), 
MOAA_SALA4  (B5F079), MOAA_SALDC  (B5FP68), MOAA_SALEP  (B5QX73), 
MOAA_SALG2  (B5R769), MOAA_SALHS  (B4TC55), MOAA_SALNS  (B4SZK4), 
MOAA_SALPA  (Q5PG37), MOAA_SALPB  (A9MTH7), MOAA_SALPC  (C0PWZ0), 
MOAA_SALPK  (B5BC24), MOAA_SALSV  (B4TQU6), MOAA_SALTI  (P65387), 
MOAA_SALTY  (P65386), MOAA_SHIB3  (B2TVE9), MOAA_SHIBS  (Q324B1), 
MOAA_SHIDS  (Q32I50), MOAA_SHIFL  (Q83S40), MOAA_SHISS  (Q3Z403), 
MOAA_SINMW  (A6U9U3), MOAA_STAA1  (A7X5J1), MOAA_STAA2  (A6U3Z2), 
MOAA_STAA3  (Q2FEM4), MOAA_STAA8  (P69848), MOAA_STAA9  (A5IV50), 
MOAA_STAAB  (Q2YYS8), MOAA_STAAC  (Q5HDT9), MOAA_STAAE  (A6QJA8), 
MOAA_STAAM  (Q931G4), MOAA_STAAN  (P65388), MOAA_STAAR  (Q6GEG6), 
MOAA_STAAS  (Q6G754), MOAA_STAAT  (A8Z366), MOAA_STAAW  (P65389), 
MOAA_STACT  (Q9ZIM6), MOAA_STAEQ  (Q5HLY1), MOAA_STAES  (Q8CNE6), 
MOAA_STAHJ  (Q4L8D2), MOAA_STAS1  (Q49ZI6), MOAA_STRCO  (Q9RJ47), 
MOAA_STRM5  (B4SL67), MOAA_STRMK  (B2FUM0), MOAA_SULDN  (Q30P92), 
MOAA_SULNB  (A6Q6R2), MOAA_SULTO  (Q971H1), MOAA_SYNE7  (Q56211), 
MOAA_SYNJB  (Q2JI46), MOAA_SYNP6  (Q5N5F7), MOAA_SYNWW  (Q0AVU6), 
MOAA_SYNY3  (Q55369), MOAA_THEAC  (Q9HKZ7), MOAA_THEVO  (Q979T0), 
MOAA_THEYD  (B5YJ09), MOAA_TOLAT  (C4LFK3), MOAA_TRIEI  (Q119N9), 
MOAA_TRIV2  (Q3MC34), MOAA_XANAC  (Q8PNH1), MOAA_XANC8  (Q4URN0), 
MOAA_XANCB  (B0RTE0), MOAA_XANCP  (Q8PBX1), MOAA_YERPE  (Q8ZGW5), 
MOCS1_BOVIN (Q1JQD7), MOCS1_CAEEL (Q20624), MOCS1_DICDI (Q54NM6), 
MOCS1_DROME (Q8IQF1), MOCS1_HUMAN (Q9NZB8), MOCS1_MOUSE (Q5RKZ7), 
NEOEP_STRFR (Q53U14), NIFB_AZOVI  (P11067), NIFB_BRADU  (P06770), 
NIFB_CHLTE  (Q8KC85), NIFB_FRAAL  (P46044), NIFB_HERSE  (P27714), 
NIFB_KLEOX  (P56265), NIFB_KLEPN  (P10390), NIFB_NOSS1  (P20627), 
NIFB_RHILE  (P09825), NIFB_RHILT  (P24427), NIFB_RHIME  (P09824), 
NIFB_RHOCA  (P17434), NIFB_SINFN  (Q53205), NIFB_TRIAZ  (Q43883), 
PQQE_ACIAD  (Q6F9I9), PQQE_ACIB3  (B7H2Y0), PQQE_ACIB5  (B7I6M8), 
PQQE_ACIBC  (B2I0I5), PQQE_ACIBY  (B0V494), PQQE_ACICA  (P07782), 
PQQE_AZOVD  (C1DEW5), PQQE_BRADU  (Q89FG1), PQQE_ECTM1  (A4XTR4), 
PQQE_ERWT9  (B2VL10), PQQE_GLUOX  (Q9L3B0), PQQE_GRABC  (Q0BQS8), 
PQQE_KLEP3  (B5XX58), PQQE_KLEP7  (A6T9H2), PQQE_KLEPN  (P27507), 
PQQE_KLUIN  (P59748), PQQE_METC4  (B7KXC6), PQQE_METCA  (Q608P0), 
PQQE_METEA  (P71517), PQQE_METEP  (A9W3R0), PQQE_METNO  (B8ITV7), 
PQQE_METPB  (B1ZIB2), PQQE_METRJ  (B1LUE7), PQQE_METS4  (B0UE13), 
PQQE_PSE14  (Q48CT3), PQQE_PSEA8  (B7VAB6), PQQE_PSEAB  (Q02LD6), 
PQQE_PSEAE  (Q9I2C0), PQQE_PSEF5  (Q4K4U8), PQQE_PSEP1  (A5VXG4), 
PQQE_PSEPK  (Q88QV8), PQQE_PSESM  (Q88A84), PQQE_PSEU2  (Q4ZMC1), 
PQQE_PSEVU  (Q01060), PQQE_RHOPA  (Q6N8F3), SKFB_BACSU  (O31423)
» more

UniProtKB/Swiss-Prot
False negative sequences		 56 sequences 

AHBC_METBF  (Q46BK8), AHBD_METBF  (Q46CH7), AHBD_NITV2  (Q72DS4), 

AHBD_OLEA2  (Q30Y73), MOAA_HYDCU  (Q31JB9), MOAA_MANSM  (Q65TT2), 
MOAA_METAR  (Q0W3L5), MOAA_METKA  (Q8TV60), MOAA_METM5  (A4FYQ8), 
MOAA_METM6  (A9A661), MOAA_METM7  (A6VJM2), MOAA_METMP  (Q6LZQ3), 
MOAA_METVS  (A6US67), MOAA_PARMW  (Q7U3H2), MOAA_PSYIN  (A1SWQ3), 
MOAA_PYRAE  (Q8ZYE5), MOAA_RHOJR  (Q0S2N2), MOAA_RHOOB  (C1B1N5), 
MOAA_SACI1  (C3NGB5), MOAA_SACI2  (C3MR64), MOAA_SACI3  (C3MZ99), 
MOAA_SACI4  (C3MXF3), MOAA_SACI6  (C4KIH7), MOAA_SACI7  (C3N7B9), 
MOAA_SACS2  (Q980F0), MOAA_SHEDO  (Q12T28), MOAA_SULAC  (Q4J8T0), 
MOAA_SYNPW  (Q9EYN8), MOAA_SYNS9  (Q3AVP9), MOAA_SYNSC  (Q3AGB7), 
MOAA_THEKO  (Q5JHN5), MOAA_VIBA3  (B7VLU4), MOAA_VIBC3  (A5F2Q5), 
MOAA_VIBCH  (Q9KT81), MOAA_VIBCM  (C3LTS1), MOAA_VIBPA  (Q87MY0), 
MOAA_VIBVU  (Q8D894), MOAA_VIBVY  (Q7MM75), NIFB_METIM  (D5VRM1), 
NIFB_METJA  (Q58493), NIRJ_DINSH  (A8LLZ7), NIRJ_PARPN  (A0A1I5E523), 
PQQE_ACIBS  (B0VQD7), PQQE_METSB  (B8ENI9), PQQE_RAHAQ  (O33506), 
PQQE_RHIME  (Q9EXU8), PQQE_RUEPO  (Q5LTB4), PQQE_STRRO  (P59749), 
PQQE_XANAC  (Q8PHY1), PQQE_XANC8  (Q4UXI4), PQQE_XANCB  (B0RQ25), 
PQQE_XANCP  (Q8P6M7), PQQE_XANE5  (Q3BQI4), PQQE_XANOM  (Q2P4Y9), 
PQQE_XANOP  (B2SSW3), PQQE_XANOR  (Q5H234)
» more

UniProtKB/Swiss-Prot
'Unknown' sequences		 1 sequence 

SAND_FLAPC  (A0A1S1YUU1)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			13 sequences
			


			
BCHQ_CHLTE  (Q8KBK9), MIAB_HERA2  (A9AZY8), MIAB_OPITP  (B1ZVI7), 

			
MIAB_ROSS1  (A5UUG7), RIMO_CHLAA  (A9WDA3), RIMO_HERA2  (A9AZS3), 
RIMO_ROSCS  (A7NIS8), RIMO_ROSS1  (A5UQQ2), SAND_LACM4  (P0DW53), 
Y285_HELPJ  (Q9ZMF0), Y285_HELPY  (P56130), Y804_METJA  (Q58214), 
Y907_METJA  (Q58317)


			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			6 PDB
			


			pdb_00001tv7; pdb_00001tv8; pdb_00002fb2; pdb_00002fb3; pdb_00006c8v; pdb_00006efn