PROSITE entry PS50263
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General information about the entry
| Entry name [info] | CN_HYDROLASE |
| Accession [info] | PS50263 |
| Entry type [info] | MATRIX |
| Date [info] |
01-DEC-2002 CREATED;
10-MAY-2017 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC50263 |
| Associated ProRule [info] | PRU00054 |
Name and characterization of the entry
| Description [info] | Carbon-nitrogen hydrolase domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=252; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=247; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.9488945; R2=0.0078549; TEXT='-LogE'; /CUT_OFF: LEVEL=0; SCORE=1089; N_SCORE=10.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=580; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-38; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-380; BD=-380; /M: SY='V'; M= -12,-119, -85, -83, 23,-128,-119, 21, -66, 24, 39, -61, -45,-119, -79,-115, -75, 68, 38, 27; /M: SY='Q'; M=-108,-126, -69, -11,-125, -23, 1, -53, 41, -47,-109, 0, -21, 79, 58, -27, 23, -57,-125,-112; /M: SY='V'; M= 2,-119,-122,-119, -34, 22, 2, 25,-118, 11, -55,-116, 27, -41,-122, -58, 4, 63,-127,-110; /M: SY='A'; M= 74, -47, -9, -65, -81, 12, -54, -58, -82, -56, -45, 56, -50, -68, -82, -15, 3, -32,-128, -65; /M: SY='I'; M= 26, -7,-126, -75,-101, -96,-124, 59,-120, 31, 4,-120, -53,-118,-123, -64, -1, 53,-126, -67; /M: SY='V'; M= 17, 43, -2, -19,-111, -35,-121, 27, -85, -50,-100, -78, 43, -83, -87, -23, -11, 63,-130, -46; /M: SY='Q'; M= -9, -13,-102, -50,-130,-112, -99,-120, -92, -46,-106, 30, -51, 122, -46, -26, 10,-119,-124,-111; /M: SY='Y'; M= 26, -55, 7, -21, -1, -59, 16, -48, -77, 28, -8, 9, 24, 18, 6, 3, -33, -78,-117, 34; /M: SY='N'; M= 15, -58, -25, 43, -43, -38, -15, -44, -2, 5, 5, 51, 2, 30, -2, 2, -48, -40,-127,-112; /M: SY='P'; M= -31, -20, -55, -19, -38, -61, -60, -14, 59, -43, 22, -51, 62, 28, -37, -15, 12, -2,-122, -13; /M: SY='W'; M= -28,-125, -16, -85, 15, -29,-119, -20, -33, -35, -8,-114, 48, -16, -21, 11, 24, 19, 115, -35; /M: SY='W'; M= 2,-122, 44, -32, -6,-116,-111, -4, -36, 11, -56, 15, 14, -34, 12, 9, 5, -13, 73, -12; /I: I=-22; MI=0; MD=-55; IM=0; DM=-55; /M: SY='E'; M= 14, -56, -7, 46, -13, 17,-113,-118, -52, 0, 19, 7, -4, -27, -29, -7, -27, -83,-127, -19; D=-22; /I: I=-22; DM=-55; /M: SY='D'; M= -12,-125, 79, 31, -67, -26, -15, -64, -28, -33,-115, 12, -46, 37, -59, -3, -35, -28,-132, -13; D=-22; /I: I=-22; DM=-55; /M: SY='L'; M= -14, -30, -72, -83, 33, -87,-115, 2, 2, 41, 12, -60, -2, -37, 19, -31, -8, 19, -4, -22; D=-22; /I: I=-22; DM=-55; /M: SY='E'; M= 28,-122, 11, 50,-118, -83, -38, -55, 9, -5, -42, 2, 4, 26, -6, 10, -12, -97, 47, -40; /M: SY='A'; M= 41,-120, 14, 38, -71, 6, 11,-118, 6, -47, -18, 3, -25, 21, 1, -9, 7, -49,-126, -29; /M: SY='N'; M= -35,-116, -68,-107,-116, -24, -55, 7, -78, -21, -36, 95, -78, 26, -55, 6, 50, -37,-132, -56; /M: SY='L'; M= 1, -32,-125, -48, 27, -83, -21, 35, -81, 45, 33, -68, -46, -68, -59, -44, -8, 36, -36, -31; /M: SY='Q'; M= 12,-123, 49, 31,-124, -70, -57, -82, 24, -57, 4, 5,-114, 61, 28, -3, -38, -32, -36, -56; /M: SY='K'; M= -55,-123, -50, -12, -76, -50, 7, 7, 66, -21, -28, -4,-116, -4, 58, -17, 8, -24, -42, -58; /M: SY='Y'; M= 24, 16,-118, -86, -32, -88, 40, 48, -74, 5, -15, -5, -75,-112,-116, -45, 21, 2, -11, 66; /M: SY='I'; M= -4, 29, -72, 33, -64, -66, -15, 44, -2, 29, -21, -55, -73, -12, -18, -51, -17, 12, -2, -5; /M: SY='D'; M= -9,-123, 47, 42, -79, -16, -31,-124, 34,-100,-116, 10, -68, 35, 23, 27, -24, -67, -26, -51; /M: SY='L'; M= 6,-118, -52, -37, -4, -47, -63, 7, -67, 60, 55,-116,-122, 3, -78, 2, -9, -25, 7, -17; /M: SY='I'; M= 4,-118,-123, -76, -71,-123,-121, 70,-118, 12, -7,-116,-120, -62,-121, 13, 25, 40, -27, 3; /M: SY='E'; M= 21, -56, 30, 43, -53, -29, 12, -67, 6, -10, -6, -28,-115, 23, 36, -6, -11, -25,-127,-112; /M: SY='E'; M= 4,-124, -28, 65,-124, -4, -44, -18, 32, -45, -65, -26, -20, 47, 2, -4, -22, -45, -35,-115; /I: I=-24; MD=-60; /M: SY='A'; M= 83, 2,-115, -50, -62, -48, 1, -36,-112, -31, 8, -15, -18, -47, -93, -24, 0, -17,-126, -64; D=-24; /I: I=-24; MD=-60; /M: SY='A'; M= 50, -43, -76, -83, -55, -12, 7, -5, 33, -29, 13, -52, -18, -30, -6, -22, -15, -17, 21, -26; D=-24; /I: I=-24; MI=0; MD=-60; IM=0; DM=-60; /M: SY='N'; M= 15, -57, -7, 9, -78, -20, -53, -94, 16, -14, -21, 30,-121, 27, 6, 27, -50, -64,-127, 12; D=-24; /I: I=-24; DM=-60; /M: SY='Q'; M= 10, 4, -35, 5,-127, -7, -54,-123, 42, -48, -24, 22, 44, 55, 1, -47, -40, -82, -33, -53; D=-24; /I: I=-24; DM=-60; /M: SY='G'; M= -65,-125, 28, -49,-130, 83, -30,-132, 23,-130,-120, -29, 21, 3, -4, -26, -38,-127,-125,-120; /M: SY='A'; M= 70, 21, -77,-111,-114, -80, -62, -39, -40, -48, 35, -81, 28,-110, -74, -4, 8, 38,-127, -60; /M: SY='D'; M= -41, -13, 85, 17,-129, -71, 26,-127, 26,-125, -60, 33, -67, 46, -4, -15, -53, -86,-135,-114; /M: SY='L'; M= -45, -52,-132,-126, 2,-132,-120, 60,-124, 68, 8,-127,-127,-120,-124,-120,-108, 23, -31, -4; /I: I=-36; MI=0; MD=-90; IM=0; DM=-90; /M: SY='I'; M= -28,-120,-130,-125, -44,-132,-127, 81,-119, 18, -31,-123,-124,-119, 0,-117,-104, 62,-124,-105; /M: SY='V'; M= 6, 21,-128,-123, -11, -49,-127, 47,-121, 10, -49,-121,-124,-121,-123, -46, -36, 79,-127,-106; /M: SY='W'; M= -50,-122,-131,-125, 92, -14,-121, -33,-122, 29, -97,-122,-127,-124,-122,-116, 22, -80, 113, -51; /M: SY='P'; M=-112,-137,-113,-102,-133, -68,-116,-122,-109,-131,-117,-117, 129, 8,-120, -13,-105,-126,-127,-129; /M: SY='E'; M=-107,-129, -79, 119,-131,-123,-101,-132, -89,-124,-120,-104,-103, -81, -53, -63,-108,-124,-128,-121; /M: SY='T'; M= 26, 41, 10,-112, -64, -13,-110, -41,-112, 25, 17, -25,-119,-110,-116, 19, 46, -5,-119, 41; /M: SY='W'; M= 50, -19,-115, -3, 53, -3,-117, -80,-112, -68, -46,-109,-117,-109,-116, 44, 9, -41, 98, -60; /I: I=-45; MD=-115; /M: SY='I'; M= -44,-119, -62, -51, 22,-128, -44, 60,-120, 49, -45, 8,-124,-118,-122, -50, 23, 13,-121, -48; D=-45; /I: I=-45; MI=-115; IM=-115; DM=-115; /M: SY='P'; M= -60, 24, -8,-105, -42, -18, 41, -57,-108, -65, 16, -7, 89, 3, -69, 17, 27, -51,-123, 23; /I: I=-9; MD=-22; /M: SY='G'; M= -37,-129, -38,-124, 35, 78,-121, -57,-121, -61,-118, -65, 21, -45, -53, -41, -65, -32,-120, 0; D=-9; /I: I=-9; MD=-22; /M: SY='Y'; M= -74, -6, -72,-130, 44, -22, -47, 7,-126, 2, -31,-127, -49,-123,-125, -67,-120, -52, 30, 99; D=-9; /I: I=-9; MD=-22; /M: SY='P'; M= -17,-140, -19, -85, -12, 4,-126, -41, -69, -65, 21, 34, 50, -74, -67, 5,-121, -93,-142, -41; D=-9; /I: I=-9; MD=-22; /M: SY='C'; M= -47, 39, -88, -90, 38, -57, -5, -91, -64, -99,-133, -60, -41,-140, -23, -52, 7,-137, 36, 35; D=-9; /I: I=-9; MI=0; MD=-22; IM=0; DM=-22; /M: SY='W'; M= -58, -26, 1, -14, -9, -53, -63, -36, -5, -12, -69, 10, -87,-128, 0, -22, -78,-135, 14, -26; D=-9; /I: I=-9; DM=-22; /M: SY='W'; M= -24,-140, -2, 0, -20, -37, -14, -12, -20, -28, -2, -10, 7, -22, -31, -30, -16, -61, 70, -14; D=-9; /I: I=-9; DM=-22; /M: SY='W'; M= -27, 2, -1, 5, -88, -85, 23, -9, -11,-100,-125, 4, 23, -5, 2, -8, -7, -55, 31, -42; D=-9; /I: I=-9; DM=-22; /M: SY='E'; M= -56, -12, -37, 37, -5,-135, -61, -33, -7, -20, -54, -32, 25, -8, 4, -47, -15, -74, 3, 16; D=-9; /I: I=-9; DM=-22; /M: SY='Y'; M= -62, 42, 25, -47, 3,-134, -27, -80, -45, 3, 15, -52,-137, -51,-127, -18, 1, -29, -4, 56; D=-9; /I: I=-9; DM=-22; /M: SY='H'; M= -42, -26, -48, 23, -19, -94, 44, -30, -39, 5, -8, -6, 9, -33, 1, -38, -54, -32, -9, 2; D=-9; /I: I=-9; DM=-22; /M: SY='E'; M= -2,-136, 12, 47, 5,-129, -25, -57, -8, -31, -65, 3, -39, 17, -29, -35, -81, -72,-132, 5; D=-9; /I: I=-9; DM=-22; /M: SY='N'; M= -2,-131, 3, -35, -13, -91,-118, -8, -18, -2, -60, 42, 20, -2, -41, -34, -5, -31, -18, 5; D=-9; /I: I=-9; DM=-22; /M: SY='A'; M= 32,-126, -11, 5, -50, -85, -9, -28, -18, -19, -10, -13, -30, 12, -16, 30, -7, -59, -10, -18; D=-9; /I: I=-9; DM=-22; /M: SY='P'; M= -18, 14, -4, 22, -53, -71, -25, -5, -40, 18, 3, -64, 23, 9, 12, -6, -20, -33, -9, -44; D=-9; /I: I=-9; DM=-22; /M: SY='F'; M= -7, -67, 26, -16, 34, -49, -20, -28, -16, 6, -25, -21, 27, -17, -19, 8, 20, -73,-124, -21; D=-9; /I: I=-9; DM=-22; /M: SY='L'; M= -20,-124, -4, -12, -12, -11, 13, 21, -26, 21, 9, 7, -2, -17, -80, -45, -21, 17, -33, 7; D=-9; /I: I=-9; DM=-22; /M: SY='D'; M= -31, -51, 58, 28, -33, -42, 19, -62, -47, 0,-111, 15, 55, -12, -52, -1, -18, -63, -24, -8; D=-9; /I: I=-9; DM=-22; /M: SY='G'; M= -17, -19, -18, 0, -33, 51, -33, -70, -76, -39,-114, -8, -9, -2, -16, 47, 30, -83, 18, -29; D=-9; /I: I=-9; DM=-22; /M: SY='P'; M= -26,-128, 36, 52,-127, -59, 17,-120, -16, -57, -67, -26, 77, 30, -29, -15, -26, -26,-130, -62; D=-9; /I: I=-9; DM=-22; /M: SY='E'; M= 0, -4, -53, 50, 10,-117, -22, -21, -53, -7, -1, 9, -73, -5, -54, 27, -1, 27, -30, 7; D=-9; /I: I=-9; DM=-22; /M: SY='M'; M= -15, -30, -8, -20, 9, -66, -47, 3, -54, 21, 52, -86, 4, 35, -54, -32, 36, 14, 37, -27; /M: SY='Q'; M= 24,-122, 34, 40,-125, -17, -65, -86, 6, -70, -58, 4, -1, 53, 19, -7, 2, -25, -35,-115; /M: SY='R'; M= 21, -11,-116, -24, 45, -75, -31, -6, -6, -4, -21, -69, -9, 14, 53, -38, -12, -22, 38, 11; /M: SY='L'; M= -46, -49,-128, -79, 32, -96,-115, 47, -67, 67, 38, -52,-127, -70,-120, -81, -64, -20, -25, 14; /M: SY='S'; M= 22, 28, 1, -22, -41, -66, -69, -47, 13, -9, -28, -50, -69, 48, 28, 51, 6, -70,-126,-111; /M: SY='C'; M= 22, 55, 23, 47,-121, -43, -8, -59, 7, -55, -12, 17,-115, 33, 14, 6, -31, -98, -28, -20; /M: SY='L'; M= 47, -38, -75, -39, -9, -85, -64, 23, -59, 51, 43, -75, -51, -48,-117, -42, -27, 10,-121, -68; /M: SY='A'; M= 78, 65, 0, -70,-118, -38,-115, -45, -45, -21, -52, -51, -23, -46, -43, 5, -52, -15,-127, -73; /M: SY='K'; M= 12, -48, -1, 27,-123, -43, -28, -44, 57, -72, -33, -25, -27, 21, 56, -8, -11, -46,-125,-113; /I: I=-28; MI=0; MD=-70; IM=0; DM=-70; /M: SY='E'; M= -10, -12, 30, 54,-130,-118, -5,-127, 33, -88, -39, 6, -26, 30, 17, -12, 9, -83,-133,-119; D=-28; /I: I=-28; DM=-70; /M: SY='N'; M= 16, 17, -4, -42, -15, -46, 43, -62, 3, -9,-108, 62, -68, 8, -23, -50, 4,-114, 5, 43; D=-28; /I: I=-28; DM=-70; /M: SY='N'; M=-106, -51, 28, -28,-128, 47, 23,-129, 43, -72, -46, 54, -22, 26, -10, 12,-105,-126,-130,-117; D=-28; /I: I=-28; DM=-70; /M: SY='I'; M= -7, 24, -74,-118,-106, -95, -55, 64, -64, -26, 49, -28, -17, 0, -76, -12, 22, 45,-128,-109; D=-28; /I: I=-28; DM=-70; /M: SY='W'; M= 19, -43, -11, -61, 0, -75, -8, 0,-112, -26, -12, -22, 35,-111, -51, -24, 12, 12, 88, 68; /M: SY='I'; M= -36, 17,-128,-125, 0, 2,-123, 54,-122, 50, -19,-121,-125,-120, -82,-114, -19, 48,-122,-104; /M: SY='V'; M= -21, 7, -9,-119, -31, -86, -55, 58,-120, 19, -19, -58, -40,-118,-122, 8,-102, 64, 6,-106; /M: SY='I'; M= 26,-116,-123,-120, 33, -19,-119, 39,-118, 18, 36,-115,-121,-116,-120, -19, 31, 38, -36, -40; /M: SY='G'; M= -97,-121,-106,-118,-128, 96,-113,-133,-112,-132,-121, 39, -42,-110,-119, 32, -66,-128,-125,-123; /I: I=-13; MD=-32; /M: SY='M'; M= 9, 2,-122, -54, 19, 9,-116, 33,-118, -1, 57, -73, -41,-115,-121, 13, 4, 7, -34, 25; D=-13; /I: I=-13; MI=0; MD=-32; IM=0; DM=-32; /M: SY='F'; M= -21, -52,-124, -41, 45, -14,-120, 43,-119, 9, 1,-117, 9,-118,-122, -1, 9, 41, -41, -11; D=-13; /I: I=-13; DM=-32; /M: SY='E'; M= -47,-125, 34, 54, -70, -9, 21, -59, -57, -48, 39, -18, 20, -29, 43, 13, -39, -48,-127, -16; D=-13; /I: I=-13; DM=-32; /M: SY='E'; M= -11,-125, -3, 63, -18, -89, 46, -55, 24, -21, -77, -8, -41, -3, 29, -35, -45, -36, 36, -5; D=-13; /I: I=-13; DM=-32; /M: SY='R'; M= -23,-125, 32, 36,-123, -63, -20, -47, 32, -58, -57, 11, -29, 36, 55, -16, -9, -27,-127, -38; D=-13; /I: I=-13; DM=-32; /M: SY='P'; M= -62, -29, -5, 10, -30, 20, 30, -66, -3, -54,-129, -9, 39, -63, -32, -68, -48, -53,-143, -74; D=-13; /I: I=-13; MI=0; MD=-32; IM=0; DM=-32; /M: SY='H'; M= -67,-153, 1, -10, -61, 10, 17,-154, -25,-111,-144, -10, 8, -6, -57, 0,-101, -87,-157,-142; D=-13; /I: I=-13; DM=-32; /M: SY='D'; M= -41,-144, 53, -36,-143, -4, 9,-112, -63, -65,-135, -8, 23, -7, -40, -23, -13, -65, -37, -51; D=-13; /I: I=-13; DM=-32; /M: SY='N'; M= -15, -95, 13, -14,-136, 32, 5, -34, 8, -98,-125, 33, -41, 9, -4, -34, -24, -53,-140, -77; D=-13; /I: I=-13; DM=-32; /M: SY='G'; M= -34,-124, 8, -43, -32, 41, 8, -94, 3, -37, -57, 40, 1, 9, 22, 5, -4, -82,-122, 26; D=-13; /I: I=-13; DM=-32; /M: SY='R'; M= -25,-122, -9, -12, -59, -17, 23, -48, 28, -70, -9, 9, -75, 19, 37, 28, 14, 8, -31, 19; D=-13; /I: I=-13; DM=-32; /M: SY='Y'; M= -26,-123, -58,-112, -16,-124, -9, 21,-110, 45, -47,-117, 33, 42, 6, -45, -33, -2, -6, 56; /M: SY='Y'; M= -65, -63,-119, -80, 33,-124, 4, -63,-111, -47, -50, -75,-128, -38, -10,-112, -13, -78, 54, 125; /M: SY='N'; M=-109, 19, -88,-107,-120,-102, -95, -10, -98, -52, -24, 123,-121, -61, -59, -12, -33, -67,-140,-117; /M: SY='T'; M= 18, 49,-108,-109,-119, -12,-113, -76,-107,-116, -45, -47,-112, -58, -74, 66, 84, -52,-132,-115; /M: SY='Q'; M= 37, 10, -21,-108, -69, -56, 11, 17,-107, 15, 11, 19,-119, 48, -13, -10, -12, 20, -28,-109; /M: SY='V'; M= 8, -4,-125, -41, 14,-125,-118, 33,-119, 24, -4,-121,-124, -69,-120, -31, -41, 63, -5, 40; /M: SY='V'; M= 2, -15,-127,-122, 19, -47,-122, 41, -79, 38, -11, -72,-124,-119,-122, -46, -2, 57, 1, -24; /M: SY='F'; M= -39, -23,-132,-128, 73,-131,-122, 69,-124, 28, -22,-124,-127,-124,-125, -85, -75, 27, -4, -19; /M: SY='D'; M= -35, -55, 81, -13, -75, 23, 9, -66, -27, -33, -54, 44,-115, -34, -22, 35, -41,-120,-135,-115; /I: I=-42; MI=0; MD=-106; IM=0; DM=-106; /M: SY='P'; M= -8,-124, 38, -16,-128, -14, -17,-124, 10, -97,-117, 54, 74, -14, 15, 23, -46,-122,-131,-119; /I: I=-21; MI=0; MD=-53; IM=0; DM=-53; /M: SY='Q'; M= -44,-131, 38, 4,-132, -52, -4,-130, 17, -51, -80, 40, -57, 55, -16, 8, 3,-128, 20,-120; D=-21; /I: I=-21; DM=-53; /M: SY='G'; M= -64,-126, -47,-119, -58, 96,-115,-133, -33, -62,-120, -15, -33, -65, -2, -58, -54,-128,-121, -11; D=-21; /I: I=-21; DM=-53; /M: SY='E'; M= -33,-124, 17, 56,-125, -20, 4, -43, 35, -63, -62, 17, -13, 38, 8, -22, 15, -29,-129,-115; D=-21; /I: I=-21; DM=-53; /M: SY='I'; M= -60,-120, -46, -62, -25, -28,-119, 66, -31, 28, 7,-116, -34, -35, -41, -21, 6, 36,-120, 6; /M: SY='V'; M= -15,-118, -30, -27,-103, -90,-120, 42, -26, 38, -24,-117, -10, -82, -10, -9, -7, 55,-126,-108; /I: I=-42; MD=-106; /M: SY='G'; M= 28, -31, 0, -47, -7, 44, -16, -54, -39, 1, 11, 20, -40, 40,-112, 6, -52, -62, -37, -50; D=-42; /I: I=-42; MI=-106; MD=-106; IM=-106; DM=-106; /M: SY='R'; M= -37,-125,-111, -13, -36,-123, 36, 19, 47, -47,-105, -35, -70, -12, 65, -37, 12, 2, -27, -5; D=-42; /I: I=-42; DM=-106; /M: SY='Y'; M= -28,-127,-115,-114, -31,-122, 54, -46,-103, -81,-100,-112, -71, -58, 42, -33, -42, -36, -89, 121; /M: SY='R'; M= -55,-127, 52, -96, -68, -63, 64,-125, -22, -55,-112, 0, 15, -27, 88, -15,-108, -69,-128, -24; /M: SY='K'; M=-110,-125,-102, -89,-127,-117,-105,-127, 117,-125,-113, -95,-110, -18, -71,-104,-105,-122,-120,-113; /M: SY='H'; M= -44, -29, -46,-113, -49,-122, 65, 49, -72, 20, 41, 8,-121, 10, -3, -1, -1, 10, -27, 4; /I: I=-4; MD=-11; /M: SY='H'; M= -52,-127,-106, -56, 5,-119, 121, -18, 34, -70, -14, 31,-120, -26, -5, -51, -57, -87, 10, -31; D=-4; /I: I=-4; MD=-11; /M: SY='L'; M= -34,-125,-136,-128, -99,-137,-123, -3,-129, 82, -8,-135, 16,-124, -80,-128,-116, -58,-127,-110; D=-4; /I: I=-4; MD=-11; /M: SY='W'; M= -14, 0,-133,-126, 52,-130,-126, -94,-125, -34, -50,-128, 34, -46,-127,-118, -8, 59, 65, 28; D=-4; /I: I=-4; MD=-11; /M: SY='P'; M= -50, -41, 43, -48, -28, -61, 13, -79,-113, -57, -6, 19, 88, -69, -17, -83, -31, -37, -23, -73; D=-4; /I: I=-4; MD=-11; /M: SY='F'; M= -58, -19, -13, -8, 74, -8, -41, -88,-127, -25, -5, -52, 19,-128, -87, -86, -32, -12, -25, 3; D=-4; /I: I=-4; MD=-11; /M: SY='G'; M= -18,-136, -32, 25, -71, 70,-127, -26, -70,-134, -62, -68, -29,-119, -53, -50, -46, -38,-137,-133; D=-4; /I: I=-4; MD=-11; /M: SY='E'; M= -84,-144, 9, 83,-144, -48,-118, -60, -42,-140, -53, 12,-125, -65, -12,-120, -80,-138,-146, -67; D=-4; /I: I=-4; MD=-11; /M: SY='Y'; M=-135, -54,-137, -48, 37, -60, -59, -64, -17, -79,-122, -71, -1, -69, -48, -60, -18, -84, 25, 83; D=-4; /I: I=-4; MD=-11; /M: SY='W'; M=-133,-146,-144, -42, -34,-112,-139, 25, -87, -1, 15, -18,-146, -20, -6,-138, -88, 15, 75, -35; D=-4; /I: I=-4; MD=-11; /M: SY='P'; M= -60,-162, -75, 33,-158, -94,-140,-151,-131,-156,-146,-142, 88, -86,-142,-135, -90,-152, 1,-152; D=-4; /I: I=-4; MI=0; MD=-11; IM=0; DM=-11; /M: SY='F'; M= -25, -16, -29, -11, 32, -46, -33, -81, -38, -48, -22, -91, -75, 4, -16, -50, -12, -17,-142, -60; D=-4; /I: I=-4; DM=-11; /M: SY='F'; M= -71,-139, -30, -57, 58, -74, -20, -24, -47, -12, -10, -26, -79, -20, -57, -57, -79, -4, -30, 38; D=-4; /I: I=-4; DM=-11; /M: SY='D'; M= -53,-140, 47, -17, -3, -60, -53, -35, -25, -19, -31, 18, -53, 3, -25, -26, -92, -57, -24, 18; D=-4; /I: I=-4; DM=-11; /M: SY='M'; M= -23,-128, -77, -7, -2, -44,-122, 13, -54, 23, 61, -17, -3,-120,-125, -32, -36, 14,-128, -1; D=-4; /I: I=-4; DM=-11; /M: SY='P'; M=-116,-138,-118, -27,-130, -53,-120, -43, -44, -51, 17,-122, 117, -82, -96, -39, -48, -52,-130, -68; D=-4; /I: I=-4; DM=-11; /M: SY='G'; M= -35, -31, -19, -30, -30, 55, -38, -67, -6, -31, 6, -11, -33,-110, 0, 10, 33, -65, 46,-115; D=-4; /I: I=-4; DM=-11; /M: SY='D'; M= -25, -12, 45, 13, -9, 39, 43, -54, -4, -54, -11, 7, -64, -25, -62, 3, -32, -34,-131, -64; D=-4; /I: I=-4; DM=-11; /M: SY='F'; M= -66, -41, -16,-120, 57, -15,-119, 21, -58, 18, -5, -24, 29,-119, -12, -20, -15, 15,-118, -22; D=-4; /I: I=-4; DM=-11; /M: SY='E'; M= -23,-124, -12, 50, 8, 20, -46, -21, -62, -53, -35, -57, -18, 9, -15, 36, 22, -44,-127,-114; D=-4; /I: I=-4; DM=-11; /M: SY='R'; M= -8,-127, 1, -3, 23, -44, 20, -10, 2, -2, 15, -75, -2, 11, 52, -46, -32, -67, -37, 0; D=-4; /I: I=-4; DM=-11; /M: SY='G'; M= -12, -23, -40, -59, -69, 45, -37, -36, -16, -6, -8, -62, 41, -23, 6, -20, 2, 26, -33, -31; D=-4; /I: I=-4; DM=-11; /M: SY='W'; M= -39,-121, -13, 21, 15, -13, -53, 6, -28, 0,-102, -47, 8,-110, -61, -21, 40, 33, 47, -1; D=-4; /I: I=-4; DM=-11; /M: SY='W'; M= -25, 7, -6, 11, 57, -11, -26, -25, -6, -60, -21, -12, 2, -29, -45, 18, -6, -33, 64, 36; D=-4; /I: I=-4; DM=-11; /M: SY='E'; M= -14,-125, 43, 44, -53, 28, -59, -35, -13, -99, -55, -4, 7, 43, 5, -16, -34, -9,-127, -44; D=-4; /I: I=-4; DM=-11; /M: SY='T'; M= -32, -60, 13, 9, -14, 8, 6, -56, -53, -61, -56, -13, -70, 36, 10, -16, 50, -69,-133, -34; D=-4; /I: I=-4; DM=-11; /M: SY='P'; M= -25,-135, 3, -8, -48, 24,-123, -91, -4, -35,-123, -42, 54, -2, -34, -15, 12, -46,-137,-128; D=-4; /I: I=-4; DM=-11; /M: SY='F'; M= -72, -42,-136, -69, 37, -41, -35, -40, -62, -30, 4, -24, -25, -13, -45, -11, 14, -3,-133, 4; D=-4; /I: I=-4; MI=0; MD=-11; IM=0; DM=-11; /M: SY='F'; M= -98,-150, 10, -30, 17, -75,-136, -10, -50, -15, -41,-134, -3, 11, -86, -26, -32, -59,-142, -3; D=-4; /I: I=-4; DM=-11; /M: SY='P'; M= -17, -18, -85, -22, -32, -43,-137, -51, -69, -55,-129, -35, 38, -48, -13, 5, -20, 11, -33,-135; D=-4; /I: I=-4; DM=-11; /M: SY='V'; M= -53, 0, -38,-137, -1, -69,-136, -20,-135, -15, -21, -80, 3, -82, -40, -31, -16, 40,-138, 13; D=-4; /I: I=-4; DM=-11; /M: SY='F'; M= -38, -7, -54, -23, 34,-103, -38, 1, -61, -1, -64, -32, -98, -51, -67, -36, -13, 15,-134, -1; D=-4; /I: I=-4; DM=-11; /M: SY='D'; M= -40,-138, 53, 18, -81, -40, -67, -28, -9, -22, -78, -41, -55, 21, -38, -20, -20, -22, -29,-127; D=-4; /I: I=-4; DM=-11; /M: SY='T'; M= -17, -54, -19, -77, -29, -46, -63, -18, -33, -5, -38,-118, 28, -66, -79, 1, 57, -12, 30, -61; D=-4; /I: I=-4; DM=-11; /M: SY='P'; M= -8,-133, 20, -14, -22, 10, -37, -58, 29, -57,-121, 3, 47, -47, -13, -21, -41, -65, 1, -10; D=-4; /I: I=-4; DM=-11; /M: SY='G'; M= -10, -50, 10, -48, 11, 60, -51, -25, -39, -39,-116, 6, -28,-117, -81, -27, -28, -14, -33, 8; D=-4; /I: I=-4; DM=-11; /M: SY='G'; M= -37, -6,-120,-120, -2, 63, -27, -5, -97, -10, -10,-110, -18, 6, -39, -19, -1, 18, 4, -1; D=-4; /I: I=-4; DM=-11; /M: SY='K'; M= -38, 8,-107, -46,-124,-118, -51, -80, 81, -78,-113, 1, 20, -21, 56, -14, -6, -41,-125, -69; D=-4; /I: I=-4; DM=-11; /M: SY='I'; M= -27,-120,-133,-127, 55,-132,-124, 63,-125, 37, 11,-126,-127,-124,-125, -85, -72, 44, -30, -96; D=-4; /I: I=-4; DM=-11; /M: SY='G'; M= 41,-119,-113,-115,-122, 78, -23, -68, -38, -40, -47, -76,-116, -71, -49, 20, -8, -62,-123, -21; D=-4; /I: I=-4; DM=-11; /M: SY='P'; M= 9, -26,-120,-115, -19, -16, 4, 18,-116, 17, 4, -23, 51, -22,-119, -19, -2, 48,-125, -61; /M: SY='L'; M= 29, 7,-113, 6, 35, -15,-112, 4,-112, 37, 7, 18, -8, -1,-116, -3, -20, -65,-118, -40; /M: SY='I'; M= -38, -18,-123,-124,-101,-128,-125, 99,-119, -40, -39, 9,-119, -65,-124, -49, 36, -4,-125,-107; /M: SY='C'; M=-109, 159,-129,-129,-119,-124,-129,-126,-124,-116,-117,-115,-139,-132,-131,-111,-109,-113,-149,-130; /M: SY='Y'; M= -75,-129, -12, 20, 53,-124, 27, -72,-112, -73, -18, -58,-125,-109,-112,-115,-115,-113, 105, 108; /M: SY='E'; M=-110,-128, 89, 93,-133, -21,-101,-133, -95,-128,-125, -94,-108, -90,-104,-103,-107,-127,-136,-120; /M: SY='H'; M= -22,-121, 11, -40, -63, 17, 53, 53,-110, 14, 23, 8,-119, -32, -4, 2, -50, -4, -41,-106; /I: I=-33; MI=0; MD=-84; IM=0; DM=-84; /M: SY='W'; M= 2,-121,-117, -46, 23, -87, 6, 35, -50, 3, 56, 5,-121, -55, 46, -25, 9, -42, 60, -12; /M: SY='F'; M= -41,-120, -29,-118, 101, -84, 15, -45, -77, -15, 9, -6,-126, 16,-116, -28, -7, -45, -13, 35; /M: SY='P'; M= -18,-132, -41, -72, -52, 18, -1,-122, -67,-127,-116, -25, 114, -46, -54, -33, -57, -80, -28, -12; /I: I=-17; MI=0; MD=-44; IM=0; DM=-44; /M: SY='E'; M= -32,-124, 30, 83, -23, -46, -15,-117, -17, 5, -34, -22, -6, -8, -53, 3, -46, -82,-125, -20; D=-17; /I: I=-17; DM=-44; /M: SY='P'; M= -6, -59, -71, -12, 21, -55,-111, 0, -39, 41, 22, 8, 48, 22, -31, -65, -65, -15, -5, 8; D=-17; /I: I=-17; DM=-44; /M: SY='W'; M= 50, -24,-118,-112, -30, -72, 35, -10, -14, -3, -47,-111, -44,-108, -4, 19, -16, 18, 73, 26; D=-17; /I: I=-17; DM=-44; /M: SY='R'; M= 7,-123, -65, -36, -78, -62, -33, 4, -34, 3, 13,-109, -29, 21, 77, -31, -19, 4,-119, 21; D=-17; /I: I=-17; DM=-44; /M: SY='A'; M= 34,-121, 32, 28, -45, -26, 13, -10, -10, -47, -11, 6, -54, 16, -26, -23, 12, -27, -6, 32; D=-17; /I: I=-17; DM=-44; /M: SY='M'; M= 15, 42, -41, -52, 0, -68, -18, -59, -59, 33, 56, 33, -40, 10, -81, 2, -29, -46,-117, 41; D=-17; /I: I=-17; MI=0; MD=-44; IM=0; DM=-44; /M: SY='A'; M= 60, -54, -71, -79, -62, -13, -26, -15, -24, -21, -12, -3, -45, -21, 4, 1, -41, 27,-121, 21; D=-17; /I: I=-17; DM=-44; /M: SY='Q'; M= 6, -55, -4, 4, -71, -36, -8, -45, 11, 19, 26, -7, -2, 33, 29, -1, -17, -50,-121, 14; D=-17; /I: I=-17; DM=-44; /M: SY='Q'; M= 5,-124, 42, 4,-123, -32, -37, -40, 40, -40, 2, 31, -36, 65, 20, -30, -83, -57,-126, -42; D=-17; /I: I=-17; DM=-44; /M: SY='G'; M= -8,-122, -25, -82, -14, 90, -20, -92, -33,-125,-117, -12, -37, -14, -57, -10, -19, -46,-122, -61; /I: I=-16; MD=-40; /M: SY='A'; M= 66, 26, 24, 16, -62, -89, 3, -18,-109, -86, -36, -86, -42, 13,-113, -10, -17, 23, -31,-114; D=-16; /I: I=-16; MD=-40; /M: SY='E'; M= -37,-124, 3, 68, 7,-121, 16, -6, -14, -48, -18, 13,-115, 45, -36, -48, -9, 11, -37, -19; D=-16; /I: I=-16; MD=-40; /M: SY='I'; M= -93,-121, -5,-123, -18,-133, -60, 71, -61, 50, -19,-123, -53, -67,-124,-120,-108, 40, -6,-104; D=-16; /I: I=-16; MI=0; MD=-40; IM=0; DM=-40; /M: SY='I'; M= -7,-120,-130,-125, 3,-130,-122, 67,-123, 38, 21, -72, -51,-120,-124, -52, -70, 44,-120, 0; D=-16; /I: I=-16; DM=-40; /M: SY='T'; M= 18, 28,-117,-115, 19, -79,-118, 12,-114, -5, -28, -73,-118,-113,-118, 49, 59, 26,-126,-107; D=-16; /I: I=-16; DM=-40; /M: SY='N'; M= -53, -48, -74,-112, 1,-112, -21, -50, -71, -64, -60, 98, -70, -44, 20, -53, -69, -14, 52, 55; D=-16; /I: I=-16; DM=-40; /M: SY='P'; M= -24, 25, 68,-102,-126, -84,-115, -27,-113, -21, -55, 1, 86,-114,-121, -29, -19, -45, -4, -70; D=-16; /I: I=-16; MI=0; MD=-40; IM=0; DM=-40; /M: SY='S'; M= 57, -56, -31,-110,-124, 8, -64, -80, -72, -94, -2, -22, -37, 1,-115, 58, 19, -53,-130, -44; D=-16; /I: I=-16; DM=-40; /M: SY='W'; M= 50, -53,-125, -64, -55, 36, -38, -84,-117, -61, 0, -48, -18, -45,-121, -54, -57,-119, 137, -61; D=-16; /I: I=-16; DM=-40; /M: SY='W'; M= -60,-125,-126,-123, 84, -94,-111, -41,-118, -64, -51, -75, -5,-119,-119, 23, -2,-109, 106, 74; D=-16; /I: I=-16; DM=-40; /M: SY='M'; M= -59, -49, -22, -60, -56, 48, 33, -53, -29, -49, 60, 32, 55,-108, -81, -7, 18, -23,-127, -30; D=-16; /I: I=-16; DM=-40; /M: SY='Y'; M= -7, -63, 20, -31, -56, -27, 27, -18, 3, -26, 24, 39, 1, -21, -8, 17, 30, -59,-121, 41; /M: SY='S'; M= 0,-118, -22, 16,-119, -36, -33, -92, -27, -44, -56, -31, 37, 33, -54, 58, 41, 2,-127, -26; /M: SY='P'; M= -9, -48, -2, -36, -29, -85,-114, 33,-109, 30, 10, -54, 34, -49, 6, 18, 32, -13, -26, -23; /I: I=-5; MI=0; MD=-13; IM=0; DM=-13; /M: SY='G'; M= 2, -58, -87, -7, -45, 60, -64,-140, -51, -62,-132, -71,-132,-122, -11, -1, -27, -88, -37, -72; D=-5; /I: I=-5; DM=-13; /M: SY='P'; M= -46,-129, -78, 12,-124, -81, -30, -65, 32, -31, -10, -16, 96, -4, 17, 12, -76, -68,-125, -61; /I: I=-42; MI=0; MD=-106; IM=0; DM=-106; /M: SY='W'; M= 26,-123, 33, 15, 6, -62, 6, -44, -35, 21,-103, -65, -33, 5, -15, -22, -39, -48, 63, 49; /M: SY='Q'; M= -17,-126, -13, -34,-120, -80, 96, -63, -55, -4, -12, -15, -53, 96, -51, -11, -66, -31,-129,-102; /M: SY='W'; M= -24, -53, -48, -31, 0,-119, 102, -49, -79, -69, -38, -72, -78, 37, -46, -40, -8, -67, 131, 10; /I: I=-26; MI=0; MD=-67; IM=0; DM=-67; /M: SY='F'; M= -28,-124, -9, 18, 32, -80, 9, 14, -15, 22, 16,-112, -24, 19, 16, -2, -27, -8,-121, -53; D=-26; /I: I=-26; DM=-67; /M: SY='Q'; M= 9,-120, -27, 1, -52, -43, 10, -3, -79, 23, 5, 6, -41, 51, 0, 1, -4, 13, 2, -7; /M: SY='M'; M= -27, -8, -47, -28, 10, -70, 16, 23, -63, 49, 55, -73,-122, 21,-115, -21, 13, 4, -27, -66; /M: SY='A'; M= 59, -54, -15,-108,-113, -3, -3, -17,-110, 12, 42, 5,-117, 17,-113, 23, 10, -43,-126, -65; /M: SY='R'; M= -21,-125, -71, -56, -67, -66, -54, -42, 33, -59, -4, -75, -58, 68, 84, -2, -39, -14,-123,-110; /M: SY='M'; M= 58,-114,-116, -79, 4, -26, 1, -38,-112, 9, 66, -8,-118, -45,-115, 24, -9, -3,-120, -3; /M: SY='R'; M= -11,-126,-111,-105, -13, -51, 5, -46, -68,-113, 34, 29,-122, -44, 96, -40, -90, -66, 34, 39; /I: I=-9; MI=0; MD=-23; IM=0; DM=-23; /M: SY='A'; M= 98, -54,-113,-107,-123, -98,-115,-113, -56, -80,-110, -28,-114,-105,-113, 28, -56, -74,-125,-118; /M: SY='W'; M= -26,-121,-125, -81, 6, -61, -38, 60, -25, 23, 24, -65,-123, -14, -17, -77, -1, 30, 69, -4; /M: SY='E'; M= 11, -26, 14, 94,-128, -33, -6, -78, -42, -71, -40, -14,-108, 28, -32, -41, -37,-119,-129,-117; /M: SY='N'; M= -24, -22,-100, -76, -9, 11, 6, -80, -48, 0, -3, 87,-118, -47, -77, 9, 42, -60,-126, 2; /M: SY='Q'; M= -17, 0, -7, -43,-123, 62, 10,-121, -43, -11, -52, 30,-118, 63, 23, -39, -31, -58,-126,-115; /M: SY='C'; M= -11, 84,-119,-114, -72, -25,-114, 0, -1, -7, 47, -43,-123,-108, 47, -13, 10, 28,-127, -34; /M: SY='Y'; M= -6,-126, -25,-113, 58, -31,-104, -67, -74, -85,-106, 16, 67, -35,-116, -75, -16, -51, 56, 85; /M: SY='V'; M= -46, 5,-126,-122, -23,-127,-119, 8,-119, 37, 56, -68,-124,-118,-121, -41, 25, 69,-124, -4; /I: I=-13; MD=-32; /M: SY='L'; M= 26, -19,-145,-140,-116, -67,-136, -2,-139, 36, -34,-141,-144,-135,-140, -78,-125, 13,-137, 13; D=-13; /I: I=-13; MD=-32; /M: SY='A'; M= 41, -22,-136,-133, -50, -57, 12, -80,-132, -35, 3, -39,-139, -69,-135, 1, -23, 2,-140, 16; D=-13; /I: I=-13; MD=-32; /M: SY='C'; M= 30, 34,-149,-144,-138,-141,-147, -38,-144, -30, -54,-143, -8,-142,-148, -17, -33, 2,-153, -16; D=-13; /I: I=-13; MI=0; MD=-32; IM=0; DM=-32; /M: SY='N'; M= -39, -8, -18, -30,-148, -8,-126,-144,-124,-106, -71, 65, -1, 7, -43, -67, -5, -69,-156, -73; D=-13; /I: I=-13; DM=-32; /M: SY='Q'; M= 2, -1, -20, -39,-139, -3,-133, -69, -16, -22, 14, -84,-140, 19, -26, -33, -10, -30,-148, -72; D=-13; /I: I=-13; DM=-32; /M: SY='G'; M= -17, 11, -38, -11,-142, 18, -38, -88, -9, -75,-133, -50, -31, -26, 0, -29, -9, -17, 16,-136; D=-13; /I: I=-13; DM=-32; /M: SY='G'; M= -11, -32, -15, -67,-144, 57, -9, -65, -33, -71,-136, -2, -73, -21, -60, -66, -77, -99, -36, -49; D=-13; /I: I=-13; DM=-32; /M: SY='H'; M= -46, 34, -33, 3, -8, -8, 47, -52, -58, -44, -17, -79, -34,-124, -31, -1, -23, -90, -60, 7; D=-13; /I: I=-13; DM=-32; /M: SY='D'; M= -99,-144, 53, 6,-143, -74, 48, -72, -36, -73,-134, 15, -3, -5, -81, 6, -74, -79,-154, -45; D=-13; /I: I=-13; DM=-32; /M: SY='D'; M= -21, -25, 30, 0, -30, 29, -58, 24, -82, 14, -37, 3, -8, -28, -42, -7, -8, 16, -44, -24; /M: SY='R'; M= -27,-123, 5, -27, -15, -21, 8, -52, 2, -31, -5, -35, 2, 13, 69, 14, 6, 6, -41, -68; /M: SY='A'; M= 39, 10, -1, -35, 2, -16, -55, -11, -38, -7, -19, -32, -53, -30, 26, 17, -9, -1,-118, 32; /M: SY='T'; M= 27, -5, -35, -24,-110, -37, 19, -20, -19, -1, -24, -23, -6, -19, -51, 14, 59, 6,-125, 9; /M: SY='N'; M= -16, -36,-103,-112, 36, 14, -6, -76, -80, -55, -31, 84, -79, -43, -44, 23, -30, -51,-112, 64; /M: SY='Y'; M= -22, -55, -21,-112, 35, 9, -28, -58,-108, -63, 17, 36, -61, -48, -27, 14, 54, -60, 59, 59; /M: SY='G'; M= -74, -57, 9,-118,-127, 101,-116,-135, -77,-132,-122, -62,-116,-113,-122, -30, -41,-130, 12, -35; /M: SY='H'; M= -24, -29, -55, 1, -16, 26, 87, 36, -82, -54, -62, -28, 4, -7, -75, 5, -23, -2, -44, 12; /M: SY='S'; M= -21, 24,-105, -59,-120, 4, -14,-119,-106,-121,-115, -59,-112, -34,-111, 94, 51,-112,-129, -27; /M: SY='A'; M= 62, 28, -45, -73, -19, -1, -52, -13, -59, -47, 55, -76,-118, -9, -5, -4, 3, -2,-122, -3; /M: SY='I'; M= -4, -23,-130,-125, 1, -72,-124, 79,-122, -10, 43, -66, -54,-120,-124,-115, -67, 52, -23, -10; /M: SY='I'; M= -11, 13, -32, -61, 17,-129, -35, 80,-121, -55, -35,-120,-123,-120,-124, -55, -44, 52, 9, 13; /M: SY='D'; M= 27,-120, 76, -61, -40, 34,-106,-123, -72, -53, -53, 44, -69,-104, -45, 28, -49, -84, 2,-116; /M: SY='P'; M= 0,-130,-112, 11, 30, -61, -13, -50,-109, -67, -15,-116, 109, -42, -60, -11, -80, -62, -32, -53; /M: SY='W'; M= -78, -16, 70, -22, 5, -72, -17, -93, -17, -19,-113, 47,-119, 3, 14, 5, -1, -72, 76, 2; /I: I=-22; MI=0; MD=-55; IM=0; DM=-55; /M: SY='G'; M= -52,-124, -70,-122,-130, 106,-118,-137,-117,-133, -63, -56, -58,-114,-124, -29,-114,-130,-122,-125; /M: SY='R'; M= -27, -43, -8, 38,-124, -82, 16, -69, 37,-120, -31, -10, -73, 21, 66, 16, 17, -37,-128,-112; /M: SY='I'; M= -62, 12, -46, -35, -62,-128,-122, 62, -60, 16, -47, -52, -19, -30, -14, -66, 34, 49,-127, -61; /I: I=-16; MI=0; MD=-41; IM=0; DM=-41; /M: SY='L'; M= -38, -59,-127,-121, -17, -97, -21, 48, -70, 51, -12,-121, -75, 1, -58, -84, 5, 47,-122, -26; /M: SY='A'; M= 65, -55, -45, -17, -34, 16, -11,-111, -3, -82, -16, -28, 2, -28, -22, 13, -39, 3, -11, -35; /M: SY='Q'; M= -11,-125, 2, 43,-123, -3, 16, -40, -2, -29, 5, -27, -4, 69, 19, -2, -17, -57, -50, -71; /M: SY='L'; M= 24, 34, -28, -76, -46, 19,-116, -1, -47, 42, -19,-112, 24, -47, -40, -14, 9, -25,-123, -18; /M: SY='P'; M= -12, -58, 33, -13, -73, 28, 15, -66, -19, -42,-115, 25, 64, -18, -52, 38, -27, -87,-130,-118; /I: I=-38; MI=0; MD=-97; IM=0; DM=-97; /M: SY='F'; M= -72, -53, 16, 48, 59,-101, -31,-117, 13, -51, -63, -31, -14, 23, 39, -12, 3,-106, -36, -6; /M: SY='E'; M= -1,-121, -1, 43, 7, 19, 3, -54, -15, -66, -45, 30, -66, 31, -40, 22, 14, -48,-125, -43; /I: I=-42; MI=0; MD=-106; IM=0; DM=-106; /M: SY='E'; M= -53,-128, 35, 83,-130,-119,-104,-126, -29,-100,-118, -36, 39, 38, 3, -12, -11, -58,-130, -64; /I: I=-25; MI=0; MD=-63; IM=0; DM=-63; /M: SY='G'; M= 19,-123, 13, 39, -77, 70, -13,-127, -21, -50, -51, -60, -56, -2, -74, -38, 2,-120,-126,-120; /M: SY='V'; M= -25,-119,-130, -86, -27, -99,-125, 59,-122, 38, -47, -88,-126,-121, -56, -83, -13, 63, -34, -23; /M: SY='L'; M= -46, -12,-127,-100, -46, -49, -20, 49,-120, 58, -54, -40,-127, -2, -49, -80, -28, 36,-123, -20; /M: SY='Y'; M= -56, -39, 12, -34, -7, -76, -12, 6, -89, -9, -43, -44, -10, -23, -7, -18, 47, 28, -33, 65; /I: I=-42; MI=0; MD=-106; IM=0; DM=-106; /M: SY='A'; M= 80, -37, -74, -45, -38, 5, -65, -58, -51, -72,-109, -53, -67, -60, -55, 9, -4, 10,-125, -52; /M: SY='D'; M= -41,-126, 67, 60, -88, -77, -27, -76, -8, -90, -63, -13, -33, 43, -22, -10, 30,-120, -40, -46; /M: SY='V'; M= -75,-119,-131,-126, -9,-133,-124, 53,-124, 48, -19, -44, -67,-122, -65,-119, -44, 63,-123, -24; /M: SY='D'; M= -35, -73, 87, -35, -49,-114, -33, -57, -22, -88, -58, 4, 31, 6, 3, 14, 8, -88,-133, -5; /M: SY='L'; M= -46,-122,-123,-116, -2, -22,-116, -36, -34, 55, 14, -50, 53, -45, -10, -7, -7, 2, -7, -47; /I: E1=0; IE=-380; DE=-380;» more |
Numerical results [info]
| Total number of hits | 305 in 305 different sequences |
| Number of true positive hits | 305 in 305 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 1 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Archaea, Eukaryotes, Prokaryotes (Bacteria) |
| Maximum number of repetitions [info] | 1 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Feature key [info] | DOMAIN |
| Feature description [info] | CN hydrolase |
| Version [info] | 4 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
305 sequences
AGUB_ORYSJ (Q93XI4), AGUB_SOLLC (Q9XGI9), AGUB_SOLTU (Q3HVN1), AMIE_ALCBS (Q0VN20), AMIE_BACSP (Q9L543), AMIE_BRADU (Q89VS2), AMIE_BRASB (A5EDA7), AMIE_BRASO (A4Z057), AMIE_BURCH (A0B137), AMIE_BURO0 (B1K2X7), AMIE_BURO1 (Q1BP24), AMIE_DELAS (A9C011), AMIE_GEOSE (Q9RQ17), AMIE_HELAH (Q17YA2), AMIE_HELP2 (B6JKM3), AMIE_HELPG (B5ZA60), AMIE_HELPH (Q1CUK9), AMIE_HELPJ (Q9ZME1), AMIE_HELPS (B2USC5), AMIE_HELPY (O25067), AMIE_MARN8 (A1U7G1), AMIE_NOCFA (Q5Z1U0), AMIE_PSEA7 (A6V262), AMIE_PSEA8 (B7V2X1), AMIE_PSEAB (Q02QK0), AMIE_PSEAE (P11436), AMIE_PSEFS (C3K9E6), AMIE_PSEP1 (A5W2C0), AMIE_RHOE4 (C0ZNE8), AMIE_RHOER (Q01360), AMIE_THISH (B8GQ39), AMIE_VARPS (C5CWZ4), AMIF_ALLAM (B9K1J4), AMIF_BACAA (C3P6U6), AMIF_BACAC (C3LI05), AMIF_BACAH (A0RHV8), AMIF_BACAN (P59700), AMIF_BACC0 (B7JK27), AMIF_BACC2 (B7IVH6), AMIF_BACC3 (C1EPV3), AMIF_BACC4 (B7H6S5), AMIF_BACCQ (B9IW18), AMIF_BACCR (P59701), AMIF_BACCZ (Q635Y7), AMIF_BACHK (Q6HEM5), AMIF_BRADU (Q89H51), AMIF_BRASO (A4Z3G9), AMIF_HELAH (Q17WY3), AMIF_HELP2 (B6JN78), AMIF_HELPG (B5Z8N3), AMIF_HELPH (Q1CS25), AMIF_HELPJ (Q9ZJY8), AMIF_HELPS (B2UV01), AMIF_HELPY (O25836), AMIF_NITV2 (Q72CW9), AMIF_NITV4 (A1VEP0), AMIF_PHOLL (Q7N278), AMIF_PSESM (Q887D9), AMIF_PSEU2 (Q4ZXA2), BTD_BOVIN (A6QQ07), BTD_HUMAN (P43251), BTD_MOUSE (Q8CIF4), BTD_RAT (Q5FVF9), BTD_TAKRU (Q8AV84), BUP1_ARATH (Q8H183), BUP1_DICDI (Q964D8), BUP1_HUMAN (Q9UBR1), BUP1_MOUSE (Q8VC97), BUP1_PONAB (Q5RBM6), BUP1_RAT(Q03248), CHT_ALTBR (Q7Z8M6), CHT_ASPNG (A9QXE0), CHT_BOTF4 (G2XQT1), CHT_EMENI (C8V9R7), CHT_FUSSL (Q96UG7), CHT_GIBBA (P32963), CHT_GIBZE (I1RP53), CHT_LEPMC (Q9P8V3), CHT_MICSH (P32964), CHT_NEUCR (Q7RVT0), CHT_PENRW (B6HCY4), CHT_PYRTT (E3RV84), CHT_STEHR (P9WEU5), CTU_FRATT (Q5NHL7), DCAS_AGRSK (P60327), DCAS_ENSAD (Q5S260), DCAS_RHIRD (Q44185), LNT1_LEPIC (Q72PB6), LNT1_LEPIN (Q8F724), LNT1_TREDE (P61037), LNT1_TREPA (O83279), LNT2_LEPIC (Q72MD8), LNT2_LEPIN (Q8EYY4), LNT2_TREDE (P61038), LNT2_TREPA (O83432), LNT_AGRFC (Q8UID7), LNT_ALLAM (B9JZJ6), LNT_AQUAE (O67000), LNT_AZOVD (C1DMW2), LNT_BDEBA (P61032), LNT_BLOFL (Q7VRA5), LNT_BORBR (Q7WMN7), LNT_BORBU (O51253), LNT_BORPA (P61033), LNT_BORPE (P61034), LNT_BRADU (Q89WA1), LNT_BRUME (Q8YEA6), LNT_BRUSU (Q8FXT9), LNT_CAMJE (Q9PNJ9), LNT_CAUVC (Q9AC16), LNT_CHLCV (Q824Q5), LNT_CHLMU (Q9PJK8), LNT_CHLPN (Q9Z7Q1), LNT_CHLTE (Q8KCC4), LNT_CHLTR (O84539), LNT_CHRVO (Q7NQI3), LNT_COXBU (Q820B4), LNT_ECO57 (Q8XBK2), LNT_ECOL6 (Q8FJY4), LNT_ECOLI (P23930), LNT_GEOMG (Q39T32), LNT_GEOSL (P61035), LNT_GLOVI (Q7NJV1), LNT_HAEDU (Q7VM56), LNT_HAEIN (P44626), LNT_HELHP (Q7VFP7), LNT_HELPJ (Q9ZMQ0), LNT_HELPY (O24982), LNT_METCA (Q608N5), LNT_MYCS2 (A0QZ13), LNT_NEIMA (Q9JVA8), LNT_NEIMB (Q9K0A2), LNT_NITEU (Q820C9), LNT_NOSS1 (Q8YYI9), LNT_PARMW (Q7U5S4), LNT_PASMU (Q9CM14), LNT_PHOLL (Q7N750), LNT_PHOPR (Q6LNA1), LNT_PROMA (Q7VAT8), LNT_PROMM (Q7V8K1), LNT_PROMP (Q7V0G7), LNT_PSEA7 (A6V0C5), LNT_PSEA8 (B7V9D2), LNT_PSEAB (Q02SF2), LNT_PSEAE (Q9ZI86), LNT_PSEPK (Q88DN4), LNT_PSESM (Q87VX7), LNT_RALN1 (Q8Y210), LNT_RHIE6 (B3PZB2), LNT_RHILO (Q98BJ6), LNT_RHILW (B5ZMX7), LNT_RHIME (P58377), LNT_RHIR8 (B9J8B4), LNT_RHOBA (Q7UGJ8), LNT_RHOPA (P61036), LNT_RICBR (Q1RH27), LNT_RICCN (Q92IC5), LNT_RICFE (Q4ULZ6), LNT_RICPR (Q9ZDG3), LNT_RICTY (Q68X09), LNT_SALTI (Q8Z8G7), LNT_SALTY (O87576), LNT_SHEON (Q8EHP1), LNT_SHIFL (Q820C8), LNT_SINFN (C3MF13), LNT_SINMW (Q52910), LNT_SYNY3 (P74055), LNT_THEMA (Q9WZ43), LNT_THEVB (Q8DIC3), LNT_VEREI (A1WJU9), LNT_VIBCH (Q9KTE4), LNT_VIBPA (Q87RP8), LNT_VIBVU (Q8DFE4), LNT_VIBVY (Q7MN04), LNT_WIGBR (Q8D2A8), LNT_WOLSU (Q7MAR3), LNT_YERPE (Q8D124), MTNU_BACSU (O31664), NADE2_THEMA (Q9X0Y0), NADE_ACIAD (Q6F8K4), NADE_AQUAE (O67091), NADE_ARATH (Q9C723), NADE_BOVIN (Q3ZBF0), NADE_CHICK (Q5ZMA6), NADE_DICDI (Q54ML1), NADE_DROME (Q9VYA0), NADE_HUMAN (Q6IA69), NADE_MACFA (Q4R5Y2), NADE_MOUSE (Q711T7), NADE_MYCBO (P0A5L7), NADE_MYCLE (Q9CBZ6), NADE_MYCTO (P9WJJ2), NADE_MYCTU (P9WJJ3), NADE_ORYSI (A2YII8), NADE_ORYSJ (Q0D8D4), NADE_RAT(Q812E8), NADE_RHOCA (Q03638), NADE_SCHPO (O74940), NADE_SYNY3 (P74292), NADE_TREPA (O83759), NADE_XYLFA (Q9PC24), NADE_XYLFT (Q87D47), NADE_YEAST (P38795), NFT1_CAEEL (O76463), NFT1_DROME (O76464), NILP1_ARATH (Q8VYF5), NILP2_ARATH (Q94JV5), NILP3_ARATH (Q8RUF8), NIT1_ASPKW (G7XTA8), NIT1_ASPNC (A2R6M7), NIT1_BOVIN (Q32LH4), NIT1_DICDI (Q557J5), NIT1_HUMAN (Q86X76), NIT1_MOUSE (Q8VDK1), NIT1_RAT(Q7TQ94), NIT1_SYNY3 (P55175), NIT1_SYNYG (P0DP66), NIT1_YEAST (P40447), NIT1_YEREN (P0DP68), NIT2A_XENLA (Q6IR61), NIT2B_XENLA (Q6INI7), NIT2_ASPKW (G7X8S6), NIT2_ASPNC (A2RA31), NIT2_BOVIN (Q2T9R6), NIT2_DANRE (Q4VBV9), NIT2_DICDI (Q54JM9), NIT2_HUMAN (Q9NQR4), NIT2_MOUSE (Q9JHW2), NIT2_PENRW (B6HVR6), NIT2_PONAB (Q5R4L6), NIT2_RAT(Q497B0), NIT2_SCHPO (O94660), NIT2_XENTR (Q28IE5), NIT2_YEAST (P47016), NIT3_YEAST (P49954), NITR1_BRADU (Q89GE3), NITR2_BRADU (Q89PT3), NITR2_UNKP (Q6RWK4), NITR3_UNKP (Q6RWG0), NITR_PARP8 (B2JQY2), NITR_PSEU2 (Q500U1), NITR_PYRAB (Q9UYV8), NIT_ARMGA (A0A2H3E4G0), NIT_ARTBC (D4B1Q8), NIT_ASPOR (Q2U4D6), NIT_AURST (A0A0P1DJE3), NIT_FUSV7 (C7YS90), NIT_GIBMO (Q19A54), NIT_HYPVG (G9N4E3), NIT_MACPH (K2QXC4), NIT_NEUCR (V5IPE4), NIT_PAENI (Q93NG1), NIT_PICGU (A5DNJ4), NIT_RHIFH (G9AIU0), NIT_TALMQ (B6Q5I3), NIT_TRAVS (P9WEU6), NRL1_ARATH (P32961), NRL1_RHORH (Q02068), NRL2_ARATH (P32962), NRL2_RHORH (Q03217), NRL3_ARATH (P46010), NRL4A_LUPAN (Q5QGZ8), NRL4A_TOBAC (Q42965), NRL4B_LUPAN (Q3LRV4), NRL4B_TOBAC (Q42966), NRL4_ARATH (P46011), NRL4_ORYSJ (Q6H849), NRLA_ALCFA (P20960), NRLB_KLEPO (P10045), NRL_BACSX (P82605), NTA1_SCHPO (O60178), NTA1_YEAST (P40354), PPMNT_MYCBP (A0A0H3M5A8), PPMNT_MYCTU (O53493), RSAM_PSESP (Q75SP7), SYMPP_STHOU (C6KYS2), TRAB_AGRFC (Q44351), TRAB_SINFN (P55416), VNN1_BOVIN (Q58CQ9), VNN1_CANLF (Q9TSX8), VNN1_HUMAN (O95497), VNN1_MOUSE (Q9Z0K8), VNN1_PIG(Q9BDJ5), VNN2_HUMAN (O95498), VNN3_MOUSE (Q9QZ25), VNNL1_DROME (Q9NFP1), VNNL2_DROME (Q8IRR1), VNNL3_DROME (P83548), Y480_MYCTO (P9WJ00), Y480_MYCTU (P9WJ01), YAFV_ECOBD (A0A140NDS5), YAFV_ECOLI (Q47679), YAFV_STAA4 (P0DP65), YAFV_YEREN (P0DP67), YAG5_STAAU (P55177), YAG5_STALU (P55178), YAUB_SCHPO (Q10166), YBEM_ECO57 (P58054), YBEM_ECOBD (A0A140NCB4), YBEM_ECOLI (P0DP64), YCU9_SCHPO (O59829), YHCX_BACSU (P54608), YIQ5_YEAST (P40446), YOBB_ECOLI (P76280), YPQQ_PSEPH (P55176)» more
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| UniProtKB/Swiss-Prot 'Partial' sequences |
1 sequence
NRLA_ACISA (P33036) |
| PDB [Detailed view] |
71 PDB
1EMS; 1ERZ; 1F89; 1FO6; 1UF4; 1UF5; 1UF7; 1UF8; 2DYU; 2DYV; 2E2K; 2E2L; 2GGK; 2GGL; 2PLQ; 2UXY; 2W1V; 3DLA; 3IVZ; 3IW3; 3KI8; 3KLC; 3SDB; 3SEQ; 3SEZ; 3SYT; 3SZG; 4CYF; 4CYG; 4CYY; 4GYL; 4GYN; 4H5U; 4HG3; 4HG5; 4HGD; 4KZF; 4LF0; 5G3O; 5G3P; 5N6H; 5N6L; 5N6M; 5VRG; 5VRH; 5XHQ; 6FTQ; 6I00; 6I5T; 6I5U; 6NWR; 6OFB; 6OFC; 6Q3A; 7ACI; 7SLV; 7SLX; 7SLY; 8AQ2; 8AQ3; 8AQ4; 8B0K; 8B0L; 8B0M; 8B0N; 8B0O; 8B0P; 8HPC; 8PT4; 8Q2P; 8RQR » more |