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PROSITE entry PS51147


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PURL: https://purl.expasy.org/prosite/signature/PS51147

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General information about the entry

Entry name [info] PFTA
Accession [info] PS51147
Entry type [info] MATRIX
Date [info] 01-OCT-2005 CREATED;
01-OCT-2013 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00703
Associated ProRule [info] PRU00488

Name and characterization of the entry

Description [info] Protein prenyltransferases alpha subunit repeat profile.
Matrix / Profile [info] 
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=35;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=35;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.3351829; R2=0.0088513; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=900; N_SCORE=10.3; MODE=1; TEXT='R';
/CUT_OFF: LEVEL=-1; SCORE=211; N_SCORE=4.2; MODE=1; TEXT='R?';
/DEFAULT: M0=-33; D=-50; I=-50; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105;

...
 
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-105; BD=-105;
/M: SY='Y';  M= -16, -91,  44, -31, -26, -34, -73, -12, -38,  18,  24,  30, -23, -19,  -9,  -6, -31,  -2, -84,  59;
/M: SY='W';  M= -49, -92,  19, -41,   9, -89, -83,  11, -80,  39, -68, -23,   9, -79,   5,  36, -75, -18,  90,   3;
/M: SY='E';  M=  20, -92,  45,  50, -43, -49, -74, -45,  24, -19, -81,  20, -10,  15,  -9,  -8, -43, -84, -94,   4;
/M: SY='R';  M= -42, -95,  32,  46, -93, -42,  -5, -42,  32, -58, -83,  -2, -83,  18,  59,  13,  -9, -88, -96, -22;
/M: SY='E';  M=  22, -95, -20, 105, -97, -89, -74, -39, -63, -89, -86, -75, -76, -56, -72, -72, -76, -22, -98, -90;
/M: SY='L';  M= -84, -87,-102, -95,  30,-103, -87,  -4, -95,  83,  29, -99,-100, -90, -92, -93, -80,   2, -86, -66;
/M: SY='N';  M=  15, -91,   3,  46, -31, -22,  18, -48,   4, -57, -82,  49,  -4,  43, -17,  12, -26, -43, -98, -83;
/M: SY='Y';  M= -87, -92, -98, -93,  73, -99, -77,  -1,  -8,  41, -61, -94,-100, -88, -85, -89, -82, -21,  59,  81;
/M: SY='T';  M=  -7,  60, -87, -86, -76, -91, -91,  17, -84,  17, -66, -78, -88, -86, -89, -15,  78,  38,-101, -81;
/M: SY='E';  M=  -6, -91,  30,  35, -86, -31, -18,  -4,  28, -16,  18,  18, -84,  15, -17,  23,  -7, -27, -96, -18;
/M: SY='E';  M= -11, -94,  43,  58, -35, -86,  -2, -39,  37, -18, -10,  15, -83,  26,   7, -16, -75, -42, -97, -82;
/M: SY='M';  M=  29,  37, -93, -86,  -5, -46, -87,  44,  18,  34,  52, -86, -92, -21, -82, -80, -41,   4, -91, -75;
/M: SY='I';  M=  -8, -90,-101, -96,   8,-101, -93,  81, -94,  55,   4, -94, -95, -90, -95, -88, -35, -47, -88, -70;
/M: SY='E';  M= -78, -93,  17,  56,  10, -17, -74, -25,  19,   4, -13,  21, -84,  36,  14,  -8, -35, -42, -93, -78;
/M: SY='D';  M=  -4, -89,  40,  15, -33, -86, -78, -21,  26,  26,  -9,  23, -86,  -3, -34,  -3,  24, -10, -97, -80;
/M: SY='N';  M= -27,  -7,  83, -30,  -7, -78, -69, -39, -72, -53, -86,  84, -89, -25, -79, -20, -70, -22,-103,   1;
/M: SY='P';  M=  30,  -9, -82, -15,   6, -82, -85,   5, -79, -50, -78,  -1,  95,   1, -87,   0, -39, -26, -93, -85;
/M: SY='K';  M=   3, -93,   9,  25, -42, -23,  -9, -94,  68, -92, -83,  -2, -83,   7,  31,  17, -74, -89, -90,  16;
/M: SY='N';  M= -80,  -5,  11, -74,  16, -73,  39, -38, -70, -92, -83, 114, -91, -71, -77, -12, -67, -45,-106, -79;
/M: SY='Y';  M= -43, -96, -76,  14,  23, -89,  -4, -34, -76, -76, -72,  48, -29,  30, -77, -77, -79, -82, -60, 112;
/M: SY='H';  M= -41, -87, -74, -72, -89, -39,  82, -90, -73, -89, -81, -64, -82,  45, -75,  78,  49, -85,  44, -74;
/M: SY='A';  M=  59,  18, -91, -86, -25, -27, -92,  37, -86, -29, -68, -84,  -5, -85, -90,  -7,  -9,  48, -96, -82;
/M: SY='W';  M= -93,-118,-120, -98, -57, -91,-117, -91, -89, -88, -91,-113, -97, -89, -93,-100,-105,-105, 181,  -4;
/M: SY='H';  M= -45, -90,  -7, -72,  -4, -78,  94, -42, -69, -88, -79,  81, -88,  24,  -2,  26,   7, -89,-102, -16;
/M: SY='Y';  M= -87,  -5, -81, -80,  10, -92,  99, -35, -78, -75, -69, -22, -95,  34, -75, -80, -83, -84, -63, 110;
/M: SY='R';  M= -84, -98, -84, -73, -85, -96, -10, -34, -48,  16, -73, -77, -94, -62, 111, -80, -34, -83, -93, -78;
/M: SY='R';  M= -23,  18, -83, -72,  27, -90,  -9, -83,  20, -30,  -8, -76, -91,  47,  81, -20, -29, -23, -85,  15;
/M: SY='W';  M= -49, -13, -38, -18,  46,  21, -90,  -7, -15, -25, -77,  -6, -92,   1, -85, -41, -31,  -6, 128,   2;
/M: SY='V';  M= -25,  17,-100, -95,   3,-100, -93,  50, -93,  49, -55, -94, -96, -91, -94, -86, -12,  56, -91, -16;
/M: SY='L';  M=  -8, -10, -99, -92, -29, -99, -10,  42, -92,  65,   1, -94, -97, -20, -91, -87, -78,  27,  17,  -1;
/M: SY='E';  M= -26, -93,  -9,  44,   8, -13, -76, -22,  39, -53, -80, -27,  -2,  43,  20,   9,  10, -41, -92, -80;
/M: SY='N';  M= -22, -90,   2,  10, -33, -83,  44, -83,   5,   2, -10,  60, -87,  25,  30,   3,  14, -43,   7, -77;
/M: SY='F';  M=  -2, -88,   4, -42,  41, -46, -12,  14, -37,  40,  32,  -7, -92, -20, -10, -11,  13, -66, -85,   9;
/M: SY='P';  M= -26, -93,   9,   9, -30,  29,  31, -34,  33, -86,  31, -10,  42, -26, -34,  15, -14, -42, -92,   3;
/M: SY='D';  M= -27, -91,  25,  18, -87,  -4,  11, -78,  10,   2, -77,  14,  17,   1,   2,  19,   3,  15,  12, -82;
/I:         E1=0; IE=-105; DE=-105;
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 144 in 27 different sequences
Number of true positive hits 144 in 27 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 1
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 99.31 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 6
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] PS_Langendijk_Genevaux
Feature key [info] REPEAT
Feature description [info] PFTA
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 27 sequences 

FNTA_ARATH  (Q9LX33), FNTA_BOVIN  (P29702), FNTA_CANAX  (Q9Y765), 

FNTA_DICDI  (Q54RT9), FNTA_HUMAN  (P49354), FNTA_MOUSE  (Q61239), 
FNTA_PEA(O24304), FNTA_RAT(Q04631), FNTA_SCHPO  (O60052), 
FNTA_SOLLC  (P93227), FNTA_YEAST  (P29703), PGTA1_ARATH (Q8VYB7), 
PGTA2_ARATH (Q9FJ32), PGTA_BOVIN  (Q5EA80), PGTA_CANAX  (O93829), 
PGTA_DICDI  (Q55DQ4), PGTA_HUMAN  (Q92696), PGTA_MOUSE  (Q9JHK4), 
PGTA_PIG(A5A779), PGTA_PONAB  (Q5NVK5), PGTA_RAT(Q08602), 
PGTA_SCHPO  (O94412), PGTA_YEAST  (Q00618), PTAR1_DANRE (A3KPW7), 
PTAR1_HUMAN (Q7Z6K3), PTR1A_XENLA (Q0IHB3), PTR1B_XENLA (A1L3L1)
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UniProtKB/Swiss-Prot
False negative sequences		 1 sequence 

RAM1_PETHY  (A0A0M4FMK2)


				
	

	

		PDB
[Detailed view]		
		
			98 PDB
			


			pdb_00001d8d; pdb_00001d8e; pdb_00001dce; pdb_00001fpp; pdb_00001ft1; pdb_00001ft2; pdb_00001jcq; pdb_00001jcr; pdb_00001jcs; pdb_00001kzo; pdb_00001kzp; pdb_00001ld7; 
			
				pdb_00001ld8; pdb_00001ltx; pdb_00001mzc; pdb_00001n4p; pdb_00001n4q; pdb_00001n4r; pdb_00001n4s; pdb_00001n94; pdb_00001n95; pdb_00001n9a; pdb_00001ni1; pdb_00001nl4; 
				pdb_00001o1r; pdb_00001o1s; pdb_00001o1t; pdb_00001o5m; pdb_00001qbq; pdb_00001s63; pdb_00001s64; pdb_00001sa4; pdb_00001sa5; pdb_00001tn6; pdb_00001tn7; pdb_00001tn8; 
				pdb_00001tnb; pdb_00001tno; pdb_00001tnu; pdb_00001tny; pdb_00001tnz; pdb_00001x81; pdb_00002bed; pdb_00002f0y; pdb_00002h6f; pdb_00002h6g; pdb_00002h6h; pdb_00002h6i; 
				pdb_00002iej; pdb_00002r2l; pdb_00002zir; pdb_00002zis; pdb_00003c72; pdb_00003dpy; pdb_00003dra; pdb_00003dss; pdb_00003dst; pdb_00003dsu; pdb_00003dsv; pdb_00003dsw; 
				pdb_00003dsx; pdb_00003e30; pdb_00003e32; pdb_00003e33; pdb_00003e34; pdb_00003e37; pdb_00003eu5; pdb_00003euv; pdb_00003hxb; pdb_00003hxc; pdb_00003hxd; pdb_00003hxe; 
				pdb_00003hxf; pdb_00003ksl; pdb_00003ksq; pdb_00003pz1; pdb_00003pz2; pdb_00003pz3; pdb_00003pz4; pdb_00004ehm; pdb_00004gtm; pdb_00004gto; pdb_00004gtp; pdb_00004gtq; 
				pdb_00004gtr; pdb_00004gts; pdb_00004gtt; pdb_00004gtv; pdb_00004ydo; pdb_00006j6x; pdb_00006j74; pdb_00006j7f; pdb_00006j7x; pdb_00006o60; pdb_00007rn5; pdb_00007rni; 
				pdb_00008e9e; pdb_00008rdx
			
			

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