PROSITE entry PS51212
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General information about the entry
| PURL [info] | https://purl.expasy.org/prosite/signature/PS51212 |
| Entry name [info] | WSC |
| Accession [info] | PS51212 |
| Entry type [info] | MATRIX |
| Date [info] |
01-MAY-2006 CREATED;
01-OCT-2013 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51212 |
| Associated ProRule [info] | PRU00558 |
Name and characterization of the entry
| Description [info] | WSC domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=93; /DISJOINT: DEFINITION=PROTECT; N1=1; N2=93; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.6489282; R2=0.0021189; TEXT='NScore'; /CUT_OFF: LEVEL=0; SCORE=2196; N_SCORE=7.3; MODE=1; TEXT='R'; /CUT_OFF: LEVEL=-1; SCORE=1629; N_SCORE=6.1; MODE=1; TEXT='R?'; /DEFAULT: M0=-24; D=-100; I=-100; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-105; BD=-105; /M: SY='M'; M= 23, -50, 33, -34, -48, 23, -39, 4, -32, -37, 59, -32, -46, 4, 30, -2, 2, -35, -57, -42; /M: SY='W'; M= 29, -52, 13, 0, 31, -12, -38, -42, -40, -11, -38, 31, 31, -39, -45, -34, -38, -42, 71, 35; /M: SY='T'; M= -34, -47, -29, 17, -45, 13, -35, -38, -6, -44, -39, 49, -44, 23, -37, -25, 56, 12, -56, 12; /M: SY='Y'; M= -45, -56, -43, -41, 41, -50, -22, -39, -34, -35, -32, 11, -56, 34, 12, 0, -39, -42, -18, 98; /M: SY='V'; M= -39, -51, -51, -13, -29, -58, -44, 33, -9, 34, -20, -47, -54, -39, 32, -5, -35, 38, -50, 13; /M: SY='G'; M= 24, -50, -42, -50, -57, 83, -48, -54, -45, -56, -48, 4, -47, -43, -52, -26, -41, -11, -53, -53; /M: SY='C'; M= -78, 293,-118,-118, -98,-109,-118,-112,-110, -94, -94, -90,-140,-125,-122, -83, -78, -88,-158,-120; /M: SY='Y'; M= -48, -53, -55, -54, 76, -56, -29, -28, -49, 12, -26, -51, -61, -48, -46, -6, -41, -33, -16, 91; /M: SY='S'; M= -32, -48, -40, -35, -44, -43, -39, -37, 24, 16, -34, -33, 10, -29, 39, 52, 20, -12, -56, -41; /M: SY='D'; M= 15, -53, 81, 11, -55, -41, -35, -47, -31, -17, -45, -23, -45, 15, 0, 10, -33, -11, -66, -45; /I: I=-22; MD=-23; /M: SY='N'; M= -17, -56, 43, 6, -62, -42, 31, -61, 7, -62, -53, 44, 31, -32, -38, 34, -33, -57, -70, -50; D=-22; /I: I=-22; MI=0; MD=-23; IM=0; DM=-23; /M: SY='N'; M= -1, -58, 17, 15, -62, -46, 15, -59, 5, -27, -50, 41, -53, 23, -5, 18, -38, -56, -69, -51; D=-22; /I: I=-22; DM=-23; /M: SY='P'; M= 0, -59, 10, -9, -63, -11, -45, -20, -11, -61, -54, 27, 44, -39, -15, 35, -36, -53, -68, -57; D=-22; /I: I=-22; DM=-23; /M: SY='R'; M= 1, -53, -43, -38, -48, 16, -40, -6, -24, -4, -37, -36, 31, -31, 62, 24, 4, -40, -55, -44; /M: SY='T'; M= 27, -46, -2, -38, -51, 31, -44, -43, -36, -27, -41, -31, 15, -37, 7, 18, 51, -14, -58, -47; /M: SY='L'; M= -41, -48, -1, -48, 6, -8, 24, -16, -51, 64, -15, -47, -57, -46, -50, -45, 2, 13, -52, -31; /M: SY='T'; M= 44, -42, -42, -39, -43, -39, -44, -8, -8, 8, -33, -34, -44, -36, -7, 24, 57, -28, -57, -43; /M: SY='G'; M= 7, -52, 7, 30, 5, 42, -39, -45, 20, 10, -37, 4, -46, -33, -36, -33, -39, -44, -48, 4; /M: SY='P'; M= 3, -55, -38, 11, -6, 6, 25, -17, 21, -44, -38, -36, 44, 31, 8, -34, -10, 7, -51, -2; /M: SY='S'; M= -29, -48, 18, 15, -5, 9, -38, -34, -38, -42, -40, 1, -46, -33, -42, 58, -26, 30, -53, 18; /M: SY='S'; M= -32, -49, -36, 25, 35, -13, -37, -39, -10, -40, -39, -33, -46, 9, 4, 47, 21, 3, -44, 24; /M: SY='Y'; M= -10, -48, -44, -44, 27, -48, -34, -28, -12, 9, -29, 8, -1, -40, -42, 11, 30, 11, -34, 67; /M: SY='S'; M= 21, -47, 16, -6, -42, -40, -38, 11, -10, -19, -35, 22, -46, 14, -39, 32, 18, -1, -54, 13; /M: SY='W'; M= 9, -53, -47, -44, 35, 6, -37, 0, -16, -14, 19, 11, -3, 11, -42, -37, -6, -36, 70, 55; /I: I=-19; MD=-19; /M: SY='K'; M= -17, -71, -59, -50, 3, -19, 23, -64, 38, -26, -55, -52, 18, -49, -7, -53, -20, -62, -67, -52; D=-19; /I: I=-19; MD=-19; /M: SY='N'; M= -21, -73, -51, -6, -81, -59, -57, -79, 3, -81, -72, 35, -69, -4, -53, 28, -50, -74, -86, -72; D=-19; /I: I=-19; MI=0; MD=-19; IM=0; DM=-19; /M: SY='M'; M= -40, -51, -41, -34, 10, -49, -33, -26, 0, 23, 73, 37, -51, 65, -33, -37, -36, -4, -51, -32; /M: SY='T'; M= -26, -43, 5, -33, -51, -10, -39, -46, -34, -49, -44, -23, -40, 14, -40, 65, 70, -38, -62, -44; /M: SY='P'; M= -36, -53, -46, -41, -42, -51, -48, 37, 6, -32, -30, 7, 61, -40, 4, 7, -31, 43, -58, -44; /M: SY='Q'; M= 16, -50, 6, 42, -9, 16, -35, -54, -30, -52, -45, -2, -42, 49, -35, 44, -30, -48, -54, -43; /M: SY='H'; M= 18, -49, -41, -36, -34, -46, 55, -40, 10, -23, -34, -34, -46, 16, -3, -28, 50, -12, 54, 44; /M: SY='C'; M= -78, 293,-118,-118, -98,-109,-118,-112,-110, -94, -94, -90,-140,-125,-122, -83, -78, -88,-158,-120; /I: I=-30; MI=0; MD=-32; IM=0; DM=-32; /M: SY='Q'; M= -34, -50, -34, -2, -46, -43, -35, 19, -29, -5, -32, 43, -48, 57, 13, 31, -3, 5, -58, -41; /M: SY='N'; M= -5, -49, 35, 33, -56, -3, -33, -55, 10, -56, -48, 50, -42, -26, -2, 35, 14, -49, -63, -47; /M: SY='F'; M= 2, -49, -40, 9, 56, -49, 14, 18, -40, -3, 8, 36, -52, 21, -43, -38, -36, 13, -45, -24; /M: SY='C'; M= -76, 289,-115,-115, -99,-106,-115,-112,-107, -94, -94, -87,-136,-120,-120, -17, -75, -88,-156,-118; /M: SY='F'; M= 17, -50, -39, 16, 30, -7, -38, -43, -6, -10, -37, -37, 21, -33, 22, 25, 0, -40, -43, 26; /I: I=-26; MI=0; MD=-27; IM=0; DM=-27; /M: SY='Q'; M= -14, -59, -39, 25, -62, -16, 24, -59, 7, -56, 9, -37, -50, 38, -10, 34, 4, -55, -66, -50; D=-26; /I: I=-26; DM=-27; /M: SY='Q'; M= 25, -58, 1, -34, -62, -49, -45, -56, 36, -27, -48, -38, -53, 37, 15, 1, 0, -51, -63, -52; D=-26; /I: I=-26; DM=-27; /M: SY='G'; M= -29, -53, -33, 27, -59, 77, -41, -64, -35, -61, -51, 10, -44, -33, 5, 17, -39, -58, -55, -52; /M: SY='Y'; M= -16, -56, -44, -41, 46, -51, 77, -5, -40, -33, -29, -38, -54, 29, -38, -12, -41, -39, -26, 84; /M: SY='P'; M= 24, -51, -42, -34, -48, -5, 25, -39, 4, 4, -34, -37, 49, 31, 6, -5, 15, -13, -56, -43; /M: SY='Y'; M= -45, -52, -57, -55, 44, -60, -32, 3, -50, 37, -19, -55, -61, -47, -48, -48, -41, 18, -23, 86; /M: SY='A'; M= 71, -43, -49, -43, 17, 14, -47, -33, -44, -38, -36, -42, -48, -42, -48, -25, -33, 19, -47, 3; /M: SY='G'; M= 47, -48, -46, -49, -51, 68, -51, 15, -46, -44, -39, -36, -47, -44, -52, -27, -38, -5, -53, -50; /M: SY='L'; M= -41, -47, -62, -55, -22, -63, -50, 13, -55, 69, 19, -59, -60, -50, -53, -52, -38, 38, -52, -33; /M: SY='E'; M= 9, -55, -27, 61, 14, -4, -34, -17, -25, -45, -41, -35, -43, 40, 24, 0, -37, -44, -47, 8; /I: I=-30; MD=-32; /M: SY='Y'; M= 6, -63, -48, -7, 29, -7, -44, -57, -52, -55, -53, 41, -65, -50, -56, -18, -49, -57, -48, 48; D=-30; /I: I=-30; MI=-32; IM=-32; DM=-32; /M: SY='G'; M= -8, -53, -38, -43, -58, 77, 17, -63, -37, -59, -48, 10, -46, 13, 4, 17, -39, -57, -55, -49; /M: SY='W'; M= 2, -52, -2, 0, 21, 11, 47, -46, -34, -22, -38, 8, -48, 4, 6, 9, 15, -45, 53, 26; /M: SY='E'; M= 21, -55, 20, 73, -54, -15, -36, -53, 3, -48, 21, -34, -39, 16, -32, -32, -38, -48, 52, -44; /M: SY='C'; M= -78, 293,-118,-118, -98,-109,-118,-112,-110, -94, -94, -90,-140,-125,-122, -83, -78, -88,-158,-120; /M: SY='Y'; M= -50, -56, -56, -54, 69, -57, 24, -30, -49, 11, -27, -52, -61, -47, -46, -49, -46, -37, 80, 88; /M: SY='C'; M= -78, 293,-118,-118, -98,-109,-118,-112,-110, -94, -94, -90,-140,-125,-122, -83, -78, -88,-158,-120; /M: SY='G'; M= 14, -51, -1, -46, -59, 83, -46, -62, -44, -60, -51, -28, -45, -41, -51, 22, -38, -54, -54, -53; /M: SY='N'; M= -7, -48, 36, -33, 17, -10, 18, -48, -34, -48, -43, 69, -48, -34, -40, 15, 23, -46, -52, 29; /M: SY='D'; M= -5, -50, 44, -2, -55, -39, -36, -47, 12, -52, -46, 36, 32, -30, -4, 34, 20, -10, -64, -47; /M: SY='V'; M= -16, -47, -43, -1, 2, -49, -44, -1, -41, 23, -27, 0, 14, 12, -45, 15, 30, 32, -55, -37; /M: SY='P'; M= 12, -55, 26, 24, -59, -42, -40, -51, -33, -54, -46, -34, 79, 27, -41, 8, 20, -48, -59, -51; /M: SY='P'; M= 16, -50, -36, -35, -6, -37, -34, -46, -31, -23, -40, 44, 52, 5, 21, 37, -29, -45, -50, 18; /M: SY='W'; M= 13, -48, -5, -38, 25, 20, -42, -39, 2, -5, -36, 12, -47, 11, -11, 2, 32, -13, 32, -34; /M: SY='N'; M= 23, -49, -31, 20, 6, -8, -36, -49, 6, -49, -42, 38, 7, 32, -2, 13, 24, -44, -54, -41; /I: I=-21; MD=-22; /M: SY='V'; M= -1, -51, -43, 8, -42, 5, 6, 2, -42, 4, -33, -40, -1, 11, -46, 17, 19, 19, -57, -2; D=-21; /I: I=-21; MD=-22; /M: SY='S'; M= -36, -56, -45, -41, -51, 11, 21, 4, 2, -8, -39, -37, 2, 12, 19, 45, -35, -15, -60, -45; D=-21; /I: I=-21; MD=-22; /M: SY='D'; M= -3, -69, 52, 1, -67, -64, -58, -61, -55, -4, -58, -46, -64, -53, -62, -49, 21, -58, -84, -64; D=-21; /I: I=-21; MI=0; MD=-22; IM=0; DM=-22; /M: SY='S'; M= -8, -48, 45, 42, -53, -37, -35, -46, -32, -24, -45, 5, -42, -26, -38, 62, -25, -8, -63, -46; /M: SY='S'; M= 18, -46, -37, -7, 3, 22, -40, -45, -36, -47, -42, -29, -43, 33, -40, 59, 23, -15, -54, -41; /M: SY='E'; M= -6, -51, 33, 39, -48, -13, -36, -40, -6, 14, -36, 1, -45, 35, -35, 26, -32, -8, -58, -43; /M: SY='C'; M= -78, 293,-118,-118, -98,-109,-118,-112,-110, -94, -94, -90,-140,-125,-122, -83, -78, -88,-158,-120; /I: I=-30; MI=0; MD=-32; IM=0; DM=-32; /M: SY='N'; M= 5, -46, 32, -33, -51, 12, -33, -48, -33, -18, -43, 73, -46, -33, -41, 23, 31, -45, -65, -47; /M: SY='T'; M= -2, -47, -41, -36, -39, -5, 16, -13, -35, -35, 51, -32, -44, 45, -38, 22, 52, -10, -51, 25; /M: SY='K'; M= -4, -51, 6, 12, -44, -46, -38, -10, 43, -14, -37, 2, 9, -29, 7, 9, 21, -2, -53, 6; /M: SY='C'; M= -79, 288,-116,-114,-100,-108,-116,-112,-108, -95, -94, -91, 9,-123,-122, -83, -78, -89,-155,-120; /M: SY='P'; M= 2, -49, -41, 0, 38, -44, -43, -38, 8, 6, -35, -38, 53, -37, -40, 35, 21, -38, -48, -34; /M: SY='G'; M= 24, -51, -40, -49, -59, 86, -46, -62, -45, -60, -50, 14, -46, -42, -52, -25, -41, -54, -53, -54; /I: I=-26; MI=0; MD=-27; IM=0; DM=-27; /M: SY='W'; M= 0, -56, 12, 26, -34, -43, 20, -50, -29, -49, -42, 51, 10, 18, 4, -33, -37, -50, 66, 59; /M: SY='P'; M= 9, -54, -38, 13, -52, 14, 30, -44, 14, -17, -40, -37, 66, -33, -5, 9, -35, -7, -57, -46; /M: SY='Y'; M= 31, -49, -6, -9, 4, 18, -35, -41, -13, -39, 43, -35, -47, 8, -11, 15, 7, -39, -41, 45; /M: SY='E'; M= -36, -58, -19, 78, -58, -49, -31, -54, -22, -19, -42, -33, 13, 65, -29, 9, -36, -51, -56, -46; /M: SY='M'; M= -38, -49, 3, -42, 19, -51, -39, 7, -12, -10, 54, -2, 14, -41, -43, -5, 31, 23, -45, 38; /M: SY='C'; M= -78, 288,-118,-119, -95,-111,-118, -11,-110, -86, -88, -91,-137,-124,-122, -85, -78, -77,-153,-116; /M: SY='G'; M= -28, -55, -39, -5, -60, 91, -46, -68, -41, -63, -52, -29, -46, -40, -1, -28, -45, -61, -52, -54; /I: I=-30; MI=0; MD=-32; IM=0; DM=-32; /M: SY='G'; M= 24, -50, -43, -50, -56, 83, -49, -53, -46, -55, -47, -31, -46, -44, -52, -26, -3, -11, -53, -53; /M: SY='P'; M= -15, -53, 50, -3, 36, -46, -40, -36, -41, -10, -38, -35, 54, -40, -46, 18, -33, 7, -48, 16; /M: SY='N'; M= -35, -51, 31, -32, -47, 27, -33, -50, 1, -20, -43, 53, 13, 13, -37, 23, 4, -49, -54, 17; /M: SY='R'; M= 33, -50, 4, -37, -34, -45, -35, -36, -26, 6, -32, -38, -51, -32, 56, -8, 2, -5, -44, 46; /M: SY='M'; M= -44, -53, -57, -50, 10, -57, 25, 9, -49, 42, 57, -53, 34, -45, -49, -49, -40, 7, 51, 30; /M: SY='S'; M= -33, -49, 20, 9, 6, -11, -38, 31, -36, -39, -37, 39, -46, 14, -41, 48, -27, -3, -57, -39; /M: SY='V'; M= -35, -50, -53, -46, -32, -10, 24, 39, -45, 0, -22, -46, -53, 35, -46, -42, -35, 62, -53, 15; /M: SY='Y'; M= -48, -56, 2, -48, 44, -53, -21, -32, -43, -31, -30, 9, -60, -41, -42, -43, -41, -6, -14, 108; /M: SY='R'; M= -36, -51, 9, 19, 5, -50, -40, 14, -29, -11, -33, -35, -47, 30, 35, 25, 3, 21, -54, -37; /M: SY='T'; M= -37, -47, -4, -39, -34, -48, 30, -31, -36, 10, -31, 19, 10, -37, 1, -9, 61, 5, -52, 34; /M: SY='G'; M= 18, 30, 29, -7, -49, 34, -41, -6, -39, 6, -37, 2, -48, 27, -43, 16, -34, -39, -57, -46; /I: E1=0; IE=-105; DE=-105;» more |
Numerical results [info]
| Total number of hits | 43 in 31 different sequences |
| Number of true positive hits | 43 in 31 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 3 |
| Matrix type [info] | protein_domain |
| Scaling database [info] | window20 |
| Author [info] | PS_Langendijk_Genevaux |
| Feature key [info] | DOMAIN |
| Feature description [info] | WSC |
| Version [info] | 4 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
31 sequences
GLTX_GLYTI (A0A1U9VX91), KREM1_HUMAN (Q96MU8), KREM1_MOUSE (Q99N43), KREM1_RAT (Q924S4), KREM1_XENLA (Q90Y90), KREM2_HUMAN (Q8NCW0), KREM2_MOUSE (Q8K1S7), PFM_CHAGB (P84675), PK1L_ACRMI (B8UU59), PKD1_HUMAN (P98161), PKD1_MOUSE (O08852), SLG1_YEAST (P54867), WSC1_SCHPO (P87179), WSC2_YEAST (P53832), WSC3_YEAST (Q12215), WSC4_YEAST (P38739), WSCD1_ARTBC (D4AUF1), WSCD1_HUMAN (Q658N2), WSCD1_MOUSE (Q80XH4), WSCD1_RAT (Q505J3), WSCD1_XENTR (Q0IIY2), WSCD2_ARTBC (D4AUF4), WSCD2_DANRE (A2BGL3), WSCD2_HUMAN (Q2TBF2), WSCD2_MOUSE (D4PHA7), WSCK_DROME (P83097), XYLT_CAEBR (Q5QQ52), XYLT_CAEEL (Q965Q8), XYLT_DROME (Q7KVA1), XYLT_DROPS (Q5QQ53), YLU2_PICAN (P34735)» more
|
| PDB [Detailed view] |
8 PDB
5FWS; 5FWT; 5FWU; 5FWV; 5FWW; 7BZT; 7BZU; 7PZ2 |