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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE entry PS60001


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PURL: https://purl.expasy.org/prosite/signature/PS60001

Direct ScanProsite submission
General information about the entry

Entry name [info] NOS
Accession [info] PS60001
Entry type [info] PATTERN
Date [info] 01-DEC-2001 CREATED;
01-DEC-2001 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC60001

Name and characterization of the entry

Description [info] Nitric oxide synthase (NOS) signature.
Pattern [info] 
[GR]-C-[IV]-G-R-[ILS]-x-W.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.


Total number of hits 35 in 35 different sequences
Number of true positive hits 33 in 33 different sequences
Number of 'unknown' hits 2 in 2 different sequences
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 7
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 33 sequences 

NOS1_HUMAN  (P29475), NOS1_MOUSE  (Q9Z0J4), NOS1_RABIT  (O19132), 

NOS1_RAT(P29476), NOS2_BOVIN  (Q27995), NOS2_CANLF  (O62699), 
NOS2_CAPHI  (Q28314), NOS2_CAVPO  (O54705), NOS2_CHICK  (Q90703), 
NOS2_HUMAN  (P35228), NOS2_MOUSE  (P29477), NOS2_RAT(Q06518), 
NOS3_BOVIN  (P29473), NOS3_CANLF  (Q9TUX8), NOS3_HUMAN  (P29474), 
NOS3_MOUSE  (P70313), NOS3_PIG(Q28969), NOS3_RAT(Q62600), 
NOSL_BOMMO  (B1B557), NOSO_BACSU  (O34453), NOSO_DEIRA  (Q9RR97), 
NOSO_STAAC  (Q5HEK7), NOSO_STAAM  (P0A092), NOSO_STAAN  (P0A093), 
NOSO_STAAR  (Q6GFE2), NOSO_STAAS  (Q6G818), NOSO_STAAU  (P0A004), 
NOSO_STAAW  (P0A094), NOS_ANOST   (O61608), NOS_BOMMO   (Q8T8C0), 
NOS_DROME   (Q27571), NOS_LYMST   (O61309), NOS_RHOPR   (Q26240)
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 7 sequences 

NOS2_CARAU  (Q92037), NOS2_MACMU  (O46660), NOS2_ONCMY  (Q92091), 

NOS2_RABIT  (O19114), NOS3_CAVPO  (P97270), NOS3_SHEEP  (P79209), 
NOS_SQUAC   (Q9I9M2)
» more

UniProtKB/Swiss-Prot
'Unknown' sequences		 2 sequences 

NOS1_SHEEP  (Q29498), NOS2_PIG(P79290)


				
	

	

		PDB
[Detailed view]		
		
			737 PDB
			


			pdb_00001d0c; pdb_00001d0o; pdb_00001d1v; pdb_00001d1w; pdb_00001d1x; pdb_00001d1y; pdb_00001dd7; pdb_00001df1; pdb_00001dm6; pdb_00001dm7; pdb_00001dm8; pdb_00001dmi; 
			
				pdb_00001dmj; pdb_00001dmk; pdb_00001dwv; pdb_00001dww; pdb_00001dwx; pdb_00001ed4; pdb_00001ed5; pdb_00001ed6; pdb_00001foi; pdb_00001foj; pdb_00001fol; pdb_00001foo; 
				pdb_00001fop; pdb_00001i83; pdb_00001jwj; pdb_00001jwk; pdb_00001k2r; pdb_00001k2s; pdb_00001k2t; pdb_00001k2u; pdb_00001lzx; pdb_00001lzz; pdb_00001m00; pdb_00001m7v; 
				pdb_00001m7z; pdb_00001m8d; pdb_00001m8e; pdb_00001m8h; pdb_00001m8i; pdb_00001m9j; pdb_00001m9k; pdb_00001m9m; pdb_00001m9q; pdb_00001m9r; pdb_00001m9t; pdb_00001mjt; 
				pdb_00001mmv; pdb_00001mmw; pdb_00001n2n; pdb_00001noc; pdb_00001nod; pdb_00001nos; pdb_00001nse; pdb_00001nsi; pdb_00001om4; pdb_00001om5; pdb_00001p6h; pdb_00001p6i; 
				pdb_00001p6j; pdb_00001p6k; pdb_00001p6l; pdb_00001p6m; pdb_00001p6n; pdb_00001q2o; pdb_00001qom; pdb_00001qw4; pdb_00001qw5; pdb_00001qw6; pdb_00001qwc; pdb_00001r35; 
				pdb_00001rs6; pdb_00001rs7; pdb_00001rs8; pdb_00001rs9; pdb_00001vaf; pdb_00001vag; pdb_00001zvi; pdb_00001zvl; pdb_00001zzq; pdb_00001zzr; pdb_00001zzs; pdb_00001zzt; 
				pdb_00001zzu; pdb_00002amo; pdb_00002an0; pdb_00002an2; pdb_00002bhj; pdb_00002fbz; pdb_00002fc1; pdb_00002fc2; pdb_00002g6h; pdb_00002g6i; pdb_00002g6j; pdb_00002g6k; 
				pdb_00002g6l; pdb_00002g6m; pdb_00002g6n; pdb_00002g6o; pdb_00002hx2; pdb_00002hx3; pdb_00002hx4; pdb_00002nod; pdb_00002nos; pdb_00002nse; pdb_00002nsi; pdb_00002oro; 
				pdb_00002orp; pdb_00002orq; pdb_00002orr; pdb_00002ors; pdb_00002ort; pdb_00002y37; pdb_00003b3m; pdb_00003b3n; pdb_00003b3o; pdb_00003b3p; pdb_00003dqr; pdb_00003dqs; 
				pdb_00003dqt; pdb_00003dwj; pdb_00003e65; pdb_00003e67; pdb_00003e68; pdb_00003e6l; pdb_00003e6n; pdb_00003e6o; pdb_00003e6t; pdb_00003e7g; pdb_00003e7i; pdb_00003e7m; 
				pdb_00003e7s; pdb_00003e7t; pdb_00003eah; pdb_00003eai; pdb_00003ebd; pdb_00003ebf; pdb_00003ej8; pdb_00003fc5; pdb_00003hsn; pdb_00003hso; pdb_00003hsp; pdb_00003jt3; 
				pdb_00003jt4; pdb_00003jt5; pdb_00003jt6; pdb_00003jt7; pdb_00003jt8; pdb_00003jt9; pdb_00003jta; pdb_00003jws; pdb_00003jwt; pdb_00003jwu; pdb_00003jwv; pdb_00003jww; 
				pdb_00003jwx; pdb_00003jwy; pdb_00003jwz; pdb_00003jx0; pdb_00003jx1; pdb_00003jx2; pdb_00003jx3; pdb_00003jx4; pdb_00003jx5; pdb_00003jx6; pdb_00003n2r; pdb_00003n5p; 
				pdb_00003n5q; pdb_00003n5r; pdb_00003n5s; pdb_00003n5t; pdb_00003n5v; pdb_00003n5w; pdb_00003n5x; pdb_00003n5y; pdb_00003n5z; pdb_00003n60; pdb_00003n61; pdb_00003n62; 
				pdb_00003n63; pdb_00003n64; pdb_00003n65; pdb_00003n66; pdb_00003n67; pdb_00003n68; pdb_00003n69; pdb_00003n6a; pdb_00003n6b; pdb_00003n6c; pdb_00003n6d; pdb_00003n6e; 
				pdb_00003n6f; pdb_00003n6g; pdb_00003nld; pdb_00003nle; pdb_00003nlf; pdb_00003nlg; pdb_00003nlh; pdb_00003nli; pdb_00003nlj; pdb_00003nlk; pdb_00003nlm; pdb_00003nln; 
				pdb_00003nlo; pdb_00003nlp; pdb_00003nlq; pdb_00003nlr; pdb_00003nlt; pdb_00003nlu; pdb_00003nlv; pdb_00003nlw; pdb_00003nlx; pdb_00003nly; pdb_00003nlz; pdb_00003nm0; 
				pdb_00003nny; pdb_00003nnz; pdb_00003nod; pdb_00003nos; pdb_00003nqs; pdb_00003nse; pdb_00003nw2; pdb_00003pne; pdb_00003pnf; pdb_00003png; pdb_00003pnh; pdb_00003q99; 
				pdb_00003q9a; pdb_00003rqj; pdb_00003rqk; pdb_00003rql; pdb_00003rqm; pdb_00003rqn; pdb_00003rqo; pdb_00003rqp; pdb_00003svp; pdb_00003svq; pdb_00003tyl; pdb_00003tym; 
				pdb_00003tyn; pdb_00003tyo; pdb_00003ufo; pdb_00003ufp; pdb_00003ufq; pdb_00003ufr; pdb_00003ufs; pdb_00003uft; pdb_00003ufu; pdb_00003ufv; pdb_00003ufw; pdb_00004c39; 
				pdb_00004c3a; pdb_00004cam; pdb_00004can; pdb_00004cao; pdb_00004cap; pdb_00004caq; pdb_00004car; pdb_00004cdt; pdb_00004cft; pdb_00004ctp; pdb_00004ctq; pdb_00004ctr; 
				pdb_00004ctt; pdb_00004ctu; pdb_00004ctv; pdb_00004ctw; pdb_00004ctx; pdb_00004cty; pdb_00004ctz; pdb_00004cu0; pdb_00004cu1; pdb_00004cul; pdb_00004cum; pdb_00004cun; 
				pdb_00004cvg; pdb_00004cwv; pdb_00004cww; pdb_00004cwx; pdb_00004cwy; pdb_00004cwz; pdb_00004cx0; pdb_00004cx1; pdb_00004cx2; pdb_00004cx3; pdb_00004cx4; pdb_00004cx5; 
				pdb_00004cx6; pdb_00004cx7; pdb_00004d1n; pdb_00004d1o; pdb_00004d1p; pdb_00004d2y; pdb_00004d2z; pdb_00004d30; pdb_00004d31; pdb_00004d32; pdb_00004d33; pdb_00004d34; 
				pdb_00004d35; pdb_00004d36; pdb_00004d37; pdb_00004d38; pdb_00004d39; pdb_00004d3a; pdb_00004d3b; pdb_00004d3i; pdb_00004d3j; pdb_00004d3k; pdb_00004d3m; pdb_00004d3n; 
				pdb_00004d3o; pdb_00004d3t; pdb_00004d3u; pdb_00004d3v; pdb_00004d7h; pdb_00004d7i; pdb_00004d7j; pdb_00004d7o; pdb_00004eux; pdb_00004fvw; pdb_00004fvx; pdb_00004fvy; 
				pdb_00004fvz; pdb_00004fw0; pdb_00004gqe; pdb_00004ims; pdb_00004imt; pdb_00004imu; pdb_00004imw; pdb_00004imx; pdb_00004js9; pdb_00004jse; pdb_00004jsf; pdb_00004jsg; 
				pdb_00004jsh; pdb_00004jsi; pdb_00004jsj; pdb_00004jsk; pdb_00004jsl; pdb_00004jsm; pdb_00004k5d; pdb_00004k5e; pdb_00004k5f; pdb_00004k5g; pdb_00004k5h; pdb_00004k5i; 
				pdb_00004k5j; pdb_00004k5k; pdb_00004kch; pdb_00004kci; pdb_00004kcj; pdb_00004kck; pdb_00004kcl; pdb_00004kcm; pdb_00004kcn; pdb_00004kco; pdb_00004kcp; pdb_00004kcq; 
				pdb_00004kcr; pdb_00004kcs; pdb_00004luw; pdb_00004lux; pdb_00004lwa; pdb_00004lwb; pdb_00004nos; pdb_00004nse; pdb_00004uch; pdb_00004ug5; pdb_00004ug6; pdb_00004ug7; 
				pdb_00004ug8; pdb_00004ug9; pdb_00004uga; pdb_00004ugb; pdb_00004ugc; pdb_00004ugd; pdb_00004uge; pdb_00004ugf; pdb_00004ugg; pdb_00004ugh; pdb_00004ugi; pdb_00004ugj; 
				pdb_00004ugk; pdb_00004ugl; pdb_00004ugm; pdb_00004ugn; pdb_00004ugo; pdb_00004ugp; pdb_00004ugq; pdb_00004ugr; pdb_00004ugs; pdb_00004ugt; pdb_00004ugu; pdb_00004ugv; 
				pdb_00004ugw; pdb_00004ugx; pdb_00004ugy; pdb_00004ugz; pdb_00004uh0; pdb_00004uh1; pdb_00004uh2; pdb_00004uh3; pdb_00004uh4; pdb_00004uh5; pdb_00004uh6; pdb_00004uh7; 
				pdb_00004uh8; pdb_00004uh9; pdb_00004uha; pdb_00004upm; pdb_00004upn; pdb_00004upo; pdb_00004upp; pdb_00004upq; pdb_00004upr; pdb_00004ups; pdb_00004upt; pdb_00004uqr; 
				pdb_00004uqs; pdb_00004ux6; pdb_00004v3u; pdb_00004v3v; pdb_00004v3w; pdb_00004v3x; pdb_00004v3y; pdb_00004v3z; pdb_00005ad4; pdb_00005ad5; pdb_00005ad6; pdb_00005ad7; 
				pdb_00005ad8; pdb_00005ad9; pdb_00005ada; pdb_00005adb; pdb_00005adc; pdb_00005add; pdb_00005ade; pdb_00005adf; pdb_00005adg; pdb_00005adi; pdb_00005adj; pdb_00005adk; 
				pdb_00005adl; pdb_00005adm; pdb_00005adn; pdb_00005agk; pdb_00005agl; pdb_00005agm; pdb_00005agn; pdb_00005ago; pdb_00005agp; pdb_00005fj2; pdb_00005fj3; pdb_00005fvo; 
				pdb_00005fvp; pdb_00005fvq; pdb_00005fvr; pdb_00005fvs; pdb_00005fvt; pdb_00005fvu; pdb_00005fvv; pdb_00005fvw; pdb_00005fvx; pdb_00005fvy; pdb_00005fvz; pdb_00005fw0; 
				pdb_00005g0n; pdb_00005g0o; pdb_00005g0p; pdb_00005g65; pdb_00005g66; pdb_00005g67; pdb_00005g68; pdb_00005g69; pdb_00005g6a; pdb_00005g6b; pdb_00005g6c; pdb_00005g6d; 
				pdb_00005g6e; pdb_00005g6f; pdb_00005g6g; pdb_00005g6h; pdb_00005g6i; pdb_00005g6j; pdb_00005g6k; pdb_00005g6l; pdb_00005g6m; pdb_00005g6n; pdb_00005g6o; pdb_00005g6p; 
				pdb_00005g6q; pdb_00005nse; pdb_00005unr; pdb_00005uns; pdb_00005unt; pdb_00005unu; pdb_00005unv; pdb_00005unw; pdb_00005unx; pdb_00005uny; pdb_00005unz; pdb_00005uo0; 
				pdb_00005uo1; pdb_00005uo2; pdb_00005uo3; pdb_00005uo4; pdb_00005uo5; pdb_00005uo6; pdb_00005uo7; pdb_00005uo8; pdb_00005uo9; pdb_00005uoa; pdb_00005uob; pdb_00005uoc; 
				pdb_00005uod; pdb_00005vui; pdb_00005vuj; pdb_00005vuk; pdb_00005vul; pdb_00005vum; pdb_00005vun; pdb_00005vuo; pdb_00005vup; pdb_00005vuq; pdb_00005vur; pdb_00005vus; 
				pdb_00005vut; pdb_00005vuu; pdb_00005vuv; pdb_00005vuw; pdb_00005vux; pdb_00005vuy; pdb_00005vuz; pdb_00005vv0; pdb_00005vv1; pdb_00005vv2; pdb_00005vv3; pdb_00005vv4; 
				pdb_00005vv5; pdb_00005vv6; pdb_00005vv7; pdb_00005vv8; pdb_00005vv9; pdb_00005vva; pdb_00005vvb; pdb_00005vvc; pdb_00005vvd; pdb_00005vvg; pdb_00005vvn; pdb_00006auq; 
				pdb_00006aur; pdb_00006aus; pdb_00006aut; pdb_00006auu; pdb_00006auv; pdb_00006auw; pdb_00006aux; pdb_00006auy; pdb_00006auz; pdb_00006av0; pdb_00006av1; pdb_00006av2; 
				pdb_00006av3; pdb_00006av4; pdb_00006av5; pdb_00006av6; pdb_00006av7; pdb_00006cic; pdb_00006cid; pdb_00006cie; pdb_00006cif; pdb_00006ng1; pdb_00006ng2; pdb_00006ng4; 
				pdb_00006ng5; pdb_00006ng6; pdb_00006ng7; pdb_00006ng8; pdb_00006nga; pdb_00006ngb; pdb_00006ngc; pdb_00006ngd; pdb_00006nge; pdb_00006ngf; pdb_00006ngh; pdb_00006ngi; 
				pdb_00006ngj; pdb_00006ngk; pdb_00006ngl; pdb_00006ngm; pdb_00006ngn; pdb_00006ngp; pdb_00006ngq; pdb_00006ngr; pdb_00006ngs; pdb_00006ngt; pdb_00006ngu; pdb_00006ngv; 
				pdb_00006ngw; pdb_00006ngx; pdb_00006ngy; pdb_00006ngz; pdb_00006nh0; pdb_00006nh1; pdb_00006nh2; pdb_00006nh3; pdb_00006nh4; pdb_00006nh5; pdb_00006nh6; pdb_00006nh7; 
				pdb_00006nh8; pdb_00006nhb; pdb_00006nhc; pdb_00006nhd; pdb_00006nhe; pdb_00006nhf; pdb_00006nse; pdb_00006pmv; pdb_00006pmw; pdb_00006pmx; pdb_00006pmy; pdb_00006pmz; 
				pdb_00006pn0; pdb_00006pn1; pdb_00006pn2; pdb_00006pn3; pdb_00006pn4; pdb_00006pn5; pdb_00006pn6; pdb_00006pn7; pdb_00006pn8; pdb_00006pn9; pdb_00006pna; pdb_00006pnb; 
				pdb_00006pnc; pdb_00006pnd; pdb_00006pne; pdb_00006pnf; pdb_00006png; pdb_00006pnh; pdb_00006po5; pdb_00006po7; pdb_00006po8; pdb_00006po9; pdb_00006poa; pdb_00006pob; 
				pdb_00006poc; pdb_00006pot; pdb_00006pou; pdb_00006pov; pdb_00006pow; pdb_00006pox; pdb_00006poy; pdb_00006poz; pdb_00006pp0; pdb_00006pp1; pdb_00006pp2; pdb_00006pp3; 
				pdb_00006pp4; pdb_00006xcx; pdb_00006xk3; pdb_00006xk4; pdb_00006xk5; pdb_00006xk6; pdb_00006xk7; pdb_00006xk8; pdb_00006xmc; pdb_00007m56; pdb_00007nse; pdb_00007s3x; 
				pdb_00007s3y; pdb_00007s3z; pdb_00007s40; pdb_00007ts1; pdb_00007ts2; pdb_00007ts3; pdb_00007ts4; pdb_00007ts5; pdb_00007ts6; pdb_00007ts7; pdb_00007ts8; pdb_00007ts9; 
				pdb_00007tsa; pdb_00007tsb; pdb_00007tsc; pdb_00007tsd; pdb_00007tse; pdb_00007tsf; pdb_00007tsg; pdb_00007tsh; pdb_00007tsi; pdb_00007tsk; pdb_00007tsl; pdb_00007tsm; 
				pdb_00007tsn; pdb_00007tso; pdb_00007tsp; pdb_00007uam; pdb_00007uan; pdb_00007uao; pdb_00007us7; pdb_00007us8; pdb_00008fg9; pdb_00008fga; pdb_00008fgb; pdb_00008fgc; 
				pdb_00008fgd; pdb_00008fge; pdb_00008fgf; pdb_00008fgg; pdb_00008fgh; pdb_00008fgi; pdb_00008fgj; pdb_00008fgk; pdb_00008fgl; pdb_00008fgm; pdb_00008fgn; pdb_00008fgo; 
				pdb_00008fgp; pdb_00008fgq; pdb_00008fgr; pdb_00008fgs; pdb_00008fgt; pdb_00008fgu; pdb_00008fgv; pdb_00008nse; pdb_00008t1j; pdb_00008t1k; pdb_00008ufp; pdb_00008ufq; 
				pdb_00008ufr; pdb_00008ufs; pdb_00008uft; pdb_00008ufu; pdb_00009nse
			
			

			» more