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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

PROSITE References


If you refer to: Please cite:
The PROSITE database Sigrist CJA, Cuche BA, de Castro E, Coudert E, Redaschi N, Bridge A.
The PROSITE database for protein families, domains, and sites.
Nucleic Acids Res. 2026; doi: 10.1093/nar/gkaf1188 [In press]
PubMed:41263099 [Full text] [PDF version]
PROSITE methodology Sigrist CJA, Cerutti L, Hulo N, Gattiker A, Falquet L, Pagni M, Bairoch A, Bucher P.
PROSITE: a documented database using patterns and profiles as motif descriptors.
Brief Bioinform. 3:265-274(2002).
PubMed:12230035 [PDF version]
ScanProsite De Castro E, Sigrist CJA, Gattiker A, Bulliard V, Langendijk-Genevaux PS, Gasteiger E, Bairoch A, Hulo N.
ScanProsite: detection of PROSITE signature matches and ProRule-associated functional and structural residues in proteins.
Nucleic Acids Res. 2006 Jul 1;34(Web Server issue):W362-5.
PubMed:16845026 [Full text] [PDF version]
MyDomains Hulo N, Bairoch A, Bulliard V, Cerutti L, Cuche BA, de Castro E, Lachaize C, Langendijk-Genevaux PS, Sigrist CJA.
The 20 years of PROSITE.
Nucleic Acids Res. 2008 Jan;36(Database issue):D245-9.
PubMed:18003654 [Full text] [PDF version]
The ProRule database Sigrist CJA, De Castro E, Langendijk-Genevaux PS, Le Saux V, Bairoch A, Hulo N.
ProRule: a new database containing functional and structural information on PROSITE profiles.
Bioinformatics. 2005 Nov 1;21(21):4060-6. Epub 2005 Aug 9.
PubMed:16091411 [Full text] [PDF version]