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annotation rule: PRU00029

General rule information [?]

Accession PRU00029
Dates 12-DEC-2003 (Created)
19-NOV-2022 (Last updated, Version 11)
Data class Domain
Predictors PROSITE; PS50143; BIR_REPEAT_2
Name BIR
Function All IAP proteins contain from one to three BIRs, and all known interactions between inhibitor of apoptosis proteins (IAPs) and other proteins are mediated by one or more BIRs.

Propagated annotation [?]


Cross-references [?]

PROSITE PS01282; BIR_REPEAT_1; 1;

Gene Ontology [?]

case <FTGroup:1>
GO:0046872; Molecular function: metal ion binding.

Keywords [?]

Zinc
Metal-binding
end case


Features [?]

From: PS50143
Key     From     To       Description   Tag   Condition   FTGroup
REPEAT     from     to       BIR #        
BINDING     35     35       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105     C   1
BINDING     38     38       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105     C   1
BINDING     55     55       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105     H   1
BINDING     62     62       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105     C   1

Additional information [?]

Size range 64-98 amino acids
Related rules None
Repeats 1-3
Topology Undefined
Example O14064 (BIR1_SCHPO)
Scope
Eukaryota
Viruses

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.


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UniProtKB rule member sequences [?]