ProRule PRU00067
General rule information
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| Accession | PRU00067 |
| Dates | 12-DEC-2003 (Created)
20-NOV-2019 (Last updated, Version 8) |
| Data class | Domain; |
| Predictors |
PROSITE; PS50216; DHHC |
Name | DHHC domain |
| Function | The Cys residue within the DHHC domain forms a stable acyl intermediate and transfers the acyl chain to the Cys residues of a target protein. |
| Scope(s) |
Eukaryota |
| Example(s) | P39010 (AKR1_YEAST); |
Propagated annotation
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Keywords
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| Acyltransferase | |
| Lipoprotein | |
| Palmitate | |
| Transferase | |
| end case | |
Gene Ontology
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| case <FT:2> | |
| GO:0019706; Molecular function:protein-cysteine S-palmitoyltransferase activity | |
Features
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| From: PS50216 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="DHHC #" | |||||||||
| ACT_SITE | 31 | 31 | /note="S-palmitoyl cysteine intermediate" | C | ||||||||
Additional information
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| Size range | 51-54 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [235] All [ 235 ]
- Retrieve set of proteins with 3D structure for this domain