PROSITE logo
Black ribbon
We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00067


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00067
General rule information [?]

Accession PRU00067
Dates 12-DEC-2003 (Created)
20-NOV-2019 (Last updated, Version 9)
Data class Domain;
Predictors PROSITE; PS50216; DHHC
Name DHHC domain
Function The Cys residue within the DHHC domain forms a stable acyl intermediate and transfers the acyl chain to the Cys residues of a target protein.
Scope(s) Eukaryota
Example(s) P39010;

Propagated annotation [?]

Keywords [?]

Acyltransferase
Lipoprotein
Palmitate
Transferase
end case

Gene Ontology [?]

case <FT:2>
GO:0019706; Molecular function:protein-cysteine S-palmitoyltransferase activity

Features [?]

From: PS50216
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="DHHC #"
ACT_SITE 31 31 /note="S-palmitoyl cysteine intermediate" C

Additional information [?]

Size range 51-54 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]