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annotation rule: PRU00076

General rule information [?]

Accession PRU00076
Dates 12-DEC-2003 (Created)
16-DEC-2016 (Last updated, Version 18)
Data class Domain
Predictors PROSITE; PS50026; EGF_3
Name EGF-like domain
Function Undefined.

Propagated annotation [?]


Cross-references [?]

PROSITE PS00022; EGF_1; 1;
PS01186; EGF_2; 1;
PS01187; EGF_CA; 0-1;

Gene Ontology [?]

case <Feature:PS50026:1-17=[DEQN]-x-[DEQN](2)-C-x(3,14)-C-x(3,7)-C-x-[DN]>
GO:0005509; Molecular function: calcium ion binding.

Keywords [?]

Calcium
end case

EGF-like domain
case <FTTag:disulf>
Disulfide bond
end case


Features [?]

case <Feature:PS50026:1-17=[DEQN]-x-[DEQN](2)-C-x(3,14)-C-x(3,7)-C-x-[DN]>
From: PS50026
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       EGF-like #; calcium-binding        
else
DOMAIN     from     to       EGF-like #        
end case

DISULFID     5     15           disulf   C-x*-C  
DISULFID     9     26           disulf   C-x*-C  
DISULFID     28     37           disulf   C-x*-C  

Additional information [?]

Size range 13-99 amino acids
Related rules None
Repeats 1-52
Topology Undefined
Example P01135 (TGFA_HUMAN)
Scope
Eukaryota
Viruses; Chordopoxvirinae

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.


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UniProtKB rule member sequences [?]