PRU00085

General rule information [?]

Accession	PRU00085
Dates	12-DEC-2003 (Created) 19-NOV-2022 (Last updated, Version 11)

Data class

Domain

Predictors

PROSITE; PS50905; FERRITIN_LIKE

Name	Ferritin-like diiron domain

Function

Proteins containing a ferritin-like diiron domain possess the ability to catalyze oxidation of Fe(2+) to Fe(3+) by O2, i.e. ferroxidase activity.

Propagated annotation [?]

Keywords [?]

case <FTGroup:1> or <FTGroup:2>

Metal-binding
Iron

end case

Features [?]

From: PS50905

Key From To Description Tag Condition FTGroup

DOMAIN from to Ferritin-like diiron #

BINDING 18 18 /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="#1 E 1

BINDING 51 51 /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="#1 E 1

BINDING 51 51 /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="#2 E 1

BINDING 96 96 /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="#2 E 1

BINDING 99 99 /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="#1 E 1

BINDING 129 129 /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="#1 E 1

BINDING 129 129 /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="#2 E 1

BINDING 132 132 /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="#2 H 1

BINDING 18 18 /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="#1 E 2

BINDING 51 51 /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="#1 E 2

BINDING 51 51 /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="#2 E 2

BINDING (Optional) 52 52 /ligand="heme b" /ligand_id="ChEBI:CHEBI:60344" /ligand_part="Fe" /ligand_part_id="ChEBI:CHEBI:18248" /note="axial binding residue M 2

BINDING 54 54 /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="#1 H 2

BINDING 99 99 /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="#2 E 2

BINDING 129 129 /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="#1 E 2

BINDING 129 129 /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="#2 E 2

BINDING 132 132 /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="#2 H 2

Additional information [?]

case <FTGroup:1> and <FTGroup:2>

Warning

Both types of iron binding amino acid-groups are present!

end case

Size range	124-191 amino acids
Related rules	None
Repeats	1
Topology	Cytoplasmic
Example	Q9AGG3 (RUBY_PORGI)
Scope	Bacteria Archaea Eukaryota Plastid

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

View rule in raw text format (no links)

UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets

Archaea [2]

Bacteria [70]

Eukaryota [78]

All [ 150 ]
Retrieve set of proteins with 3D structure for this domain

Archaea	[2]
Bacteria	[70]
Eukaryota	[78]
All	[ 150 ]