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annotation rule: PRU00090

General rule information [?]

Accession PRU00090
Dates 12-DEC-2003 (Created)
20-NOV-2019 (Last updated, Version 8)
Data class Domain
Predictors PROSITE; PS50038; FZ
Name FZ
Function Several fz domains have been shown to be both necessary and sufficient for Wg/Wnt ligand binding, strongly suggesting that the fz domain is a Wg/Wnt interacting domain.

Propagated annotation [?]

Keywords [?]

case <FTTag:disulf>
end case

Features [?]

From: PS50038
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       FZ #        
DISULFID     6     67           disulf   C-x*-C  
DISULFID     14     60           disulf   C-x*-C  
DISULFID     51     89           disulf   C-x*-C  
DISULFID     78     119           disulf   C-x*-C  
DISULFID     82     106           disulf   C-x*-C  

Additional information [?]

Size range 76-190 amino acids
Related rules None
Repeats 1-2
Topology Not cytoplasmic
Example P97299 (SFRP2_MOUSE)
Eukaryota; Metazoa


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]