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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00090


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00090
General rule information [?]

Accession PRU00090
Dates 12-DEC-2003 (Created)
20-NOV-2019 (Last updated, Version 9)
Data class Domain;
Predictors PROSITE; PS50038; FZ
Name FZ
Function Several fz domains have been shown to be both necessary and sufficient for Wg/Wnt ligand binding, strongly suggesting that the fz domain is a Wg/Wnt interacting domain.
Scope(s) Eukaryota
Metazoa
Example(s) P97299;

Propagated annotation [?]

Keywords [?]

case <FTTag:disulf>
Disulfide bond
end case

Features [?]

From: PS50038
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="FZ #"
DISULFID 6 67 disulf C-x*-C
DISULFID 14 60 disulf C-x*-C
DISULFID 51 89 disulf C-x*-C
DISULFID 78 119 disulf C-x*-C
DISULFID 82 106 disulf C-x*-C

Additional information [?]

Size range 76-190 amino acids
Related rules None
Fusion None
Repeats 1-2
Topology Not cytoplasmic

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]