ProRule PRU00090

General rule information [?]

Accession PRU00090
Dates 12-DEC-2003 (Created)
20-NOV-2019 (Last updated, Version 8)
Data class Domain;
Predictors PROSITE; PS50038; FZ
Name FZ
Function Several fz domains have been shown to be both necessary and sufficient for Wg/Wnt ligand binding, strongly suggesting that the fz domain is a Wg/Wnt interacting domain.
Scope(s) Eukaryota
Example(s) P97299 (SFRP2_MOUSE);

Propagated annotation [?]

Keywords [?]

case <FTTag:disulf>
Disulfide bond
end case

Features [?]

From: PS50038
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="FZ #"
DISULFID 6 67 disulf C-x*-C
DISULFID 14 60 disulf C-x*-C
DISULFID 51 89 disulf C-x*-C
DISULFID 78 119 disulf C-x*-C
DISULFID 82 106 disulf C-x*-C

Additional information [?]

Size range 76-190 amino acids
Related rules None
Fusion None
Repeats 1-2
Topology Not cytoplasmic


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

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UniProtKB rule member sequences [?]