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| annotation rule: PRU00090 |
General rule information
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| Accession | PRU00090 |
| Dates | 12-DEC-2003 (Created) 20-NOV-2019 (Last updated, Version 8) |
| Data class | Domain |
| Predictors | PROSITE; PS50038; FZ |
| Name | FZ |
| Function | Several fz domains have been shown to be both necessary and sufficient for Wg/Wnt ligand binding, strongly suggesting that the fz domain is a Wg/Wnt interacting domain. |
Propagated annotation
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Keywords
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case <FTTag:disulf>
end case
Features
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| From: PS50038 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | FZ # | |||||||||
| DISULFID | 6 | 67 | disulf | C-x*-C | ||||||||
| DISULFID | 14 | 60 | disulf | C-x*-C | ||||||||
| DISULFID | 51 | 89 | disulf | C-x*-C | ||||||||
| DISULFID | 78 | 119 | disulf | C-x*-C | ||||||||
| DISULFID | 82 | 106 | disulf | C-x*-C | ||||||||
Additional information
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| Size range | 76-190 amino acids |
| Related rules | None |
| Repeats | 1-2 |
| Topology | Not cytoplasmic |
| Example | P97299 (SFRP2_MOUSE) |
| Scope | Eukaryota; Metazoa |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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-
UniProtKB/Swiss-Prot sets
Eukaryota [119]
- Retrieve set of proteins with 3D structure for this domain