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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00100


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00100
General rule information [?]

Accession PRU00100
Dates 12-DEC-2003 (Created)
28-JUL-2025 (Last updated, Version 16)
Data class Domain;
Predictors PROSITE; PS50052; GUANYLATE_KINASE_2
Name Guanylate kinase-like domain
Function Undefined
Scope(s) Bacteria
Eukaryota
Viruses
Vaccinia virus
Example(s) Q9BXL7;

Propagated annotation [?]

Keywords [?]

Transferase
Kinase
ATP-binding
Nucleotide-binding

Gene Ontology [?]

GO:0005524; Molecular function:ATP binding
GO:0016301; Molecular function:kinase activity
GO:0000166; Molecular function:nucleotide binding
GO:0016740; Molecular function:transferase activity

Cross-references [?]

PROSITE PS00856; GUANYLATE_KINASE_1; 1;

Features [?]

From: PS50052
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Guanylate kinase-like #"
BINDING 8 15 /ligand="ATP"
/ligand_id="ChEBI:CHEBI:30616"

Additional information [?]

Size range 101-205 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]