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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00108


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00108
General rule information [?]

Accession PRU00108
Dates 12-DEC-2003 (Created)
20-NOV-2019 (Last updated, Version 16)
Data class Domain;
Predictors PROSITE; PS50071; HOMEOBOX_2
Name Homeobox DNA-binding domain
Function The homeobox domain binds DNA through a helix-turn-helix type of structure.
Scope(s) Eukaryota
Example(s) P56915;

Propagated annotation [?]

Comments [?]

SUBCELLULAR LOCATIONNucleus.

Keywords [?]

DNA-binding
Homeobox
Nucleus

Gene Ontology [?]

GO:0003677; Molecular function:DNA binding
GO:0005634; Cellular component:nucleus

Cross-references [?]

PROSITE PS00027; HOMEOBOX_1; 1;

Features [?]

From: PS50071
Key From To Description Tag Condition FTGroup
case <AnyFeature:PS51213>
DNA_BIND from+1 to+1 /note="Homeobox; TALE-type #"
else
DNA_BIND from+2 to+1 /note="Homeobox #"
end case

Additional information [?]

Size range 54-82 amino acids
Related rules None
Fusion None
Repeats 1-4
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]