ProRule PRU00108
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU00108 |
| Accession | PRU00108 |
| Dates | 12-DEC-2003 (Created)
20-NOV-2019 (Last updated, Version 15) |
| Data class | Domain; |
| Predictors |
PROSITE; PS50071; HOMEOBOX_2 |
Name | Homeobox DNA-binding domain |
| Function | The homeobox domain binds DNA through a helix-turn-helix type of structure. |
| Scope(s) |
Eukaryota |
| Example(s) | P56915 (GSC_HUMAN); |
Propagated annotation
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Comments
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| SUBCELLULAR LOCATION | Nucleus. |
Keywords
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Gene Ontology
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| GO:0003677; Molecular function:DNA binding |
| GO:0005634; Cellular component:nucleus |
Cross-references
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| PROSITE | PS00027; HOMEOBOX_1; 1; |
Features
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| From: PS50071 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| case <AnyFeature:PS51213> | ||||||||||||
| DNA_BIND | from+1 | to+1 | /note="Homeobox; TALE-type #" | |||||||||
| else | ||||||||||||
| DNA_BIND | from+2 | to+1 | /note="Homeobox #" | |||||||||
| end case | ||||||||||||
Additional information
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| Size range | 54-82 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1-4 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [1684] Viruses [1] All [ 1685 ]
- Retrieve set of proteins with 3D structure for this domain