General rule information
[?]
Accession |
PRU00160 |
Dates |
12-DEC-2003 (Created) 7-MAY-2020 (Last updated, Version 13) |
Predictors |
PROSITE; PS50054; TYR_PHOSPHATASE_DUAL
|
Predictors |
PROSITE; PS50055; TYR_PHOSPHATASE_PTP
|
Name |
Protein-tyrosine phosphatase domain |
Function |
Tyrosine specific protein phosphatases (EC 3.1.3.48) (PTPase) are enzymes that catalyze the removal of a phosphate group attached to a tyrosine residue. |
Propagated annotation
[?]
case <FTTag:act_site>
PROSITE |
PS00383; TYR_PHOSPHATASE_1; 1; |
end case
PROSITE |
PS50056; TYR_PHOSPHATASE_2; 1; |
case <FTTag:act_site>
GO:0008138; Molecular function: protein tyrosine/serine/threonine phosphatase activity.
GO:0004725; Molecular function: protein tyrosine phosphatase activity.
GO:0016787; Molecular function: hydrolase activity.
end case
case <Feature:PS50054>
From: any |
Key
|
|
From
|
|
To
|
|
Description
|
|
Tag
|
|
Condition
|
|
FTGroup
|
DOMAIN
|
|
from
|
|
to
|
|
Tyrosine-protein phosphatase #
|
|
|
|
|
|
|
ACT_SITE
|
|
89
|
|
89
|
|
Phosphocysteine intermediate
|
|
act_site
|
|
C
|
|
|
else case <Feature:PS50055>
DOMAIN
|
|
from
|
|
to
|
|
Tyrosine-protein phosphatase #
|
|
|
|
|
|
|
ACT_SITE
|
|
196
|
|
196
|
|
Phosphocysteine intermediate
|
|
act_site
|
|
C
|
|
|
end case
Additional information
[?]
Size range |
63-419 amino acids |
Related rules |
None |
Repeats |
1-2 |
Topology |
Undefined |
Examples |
P23469 (PTPRE_HUMAN); Q6NKR2 (TPMT2_ARATH): [Recover all] |
Scope |
Eukaryota |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and
distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives
(CC BY-NC-ND 4.0) License, see
prosite_license.html.
UniProtKB rule member sequences
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