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ProRule PRU00238


General rule information [?]

PURL https://purl.expasy.org/prosite/rule/PRU00238
Accession PRU00238
Dates 12-DEC-2003 (Created)
10-JAN-2024 (Last updated, Version 16)
Data class Domain;
Predictors PROSITE; PS01033; GLOBIN
Name Globin domain
Function Globins are heme-containing proteins involved in binding and/or transporting oxygen.
Scope(s) Eukaryota
Bacteria
Example(s) Q8WWM9 (CYGB_HUMAN);

Propagated annotation [?]

Comments [?]

case not <OC:Bacteria>
SIMILARITYBelongs to the globin family.
end case

Keywords [?]

Oxygen transport
end case
case <FTGroup:1> or <FTGroup:2>
Heme
Iron
Metal-binding
Transport
end case

Gene Ontology [?]

case <FTGroup:1> or <FTGroup:2>
GO:0006810; Biological process:transport
end case
case <FTGroup:1>
GO:0015671; Biological process:oxygen transport

Features [?]

From: PS01033
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Globin #"
case <Feature:PS01033:61-62=H-G>
BINDING 61 61 /ligand="O2"
/ligand_id="ChEBI:CHEBI:15379"		 H 1
BINDING 93 93 /ligand="heme b"
/ligand_id="ChEBI:CHEBI:60344"
/ligand_part="Fe"
/ligand_part_id="ChEBI:CHEBI:18248"
/note="proximal binding residue"		 H 1
else
BINDING 61 61 /ligand="heme b"
/ligand_id="ChEBI:CHEBI:60344"
/ligand_part="Fe"
/ligand_part_id="ChEBI:CHEBI:18248"
/note="distal binding residue"		 [HQ] 2
BINDING 93 93 /ligand="heme b"
/ligand_id="ChEBI:CHEBI:60344"
/ligand_part="Fe"
/ligand_part_id="ChEBI:CHEBI:18248"
/note="proximal binding residue"		 H 2
end case

Additional information [?]

Size range 108-151 amino acids
Related rules None
Fusion None
Repeats 1-9
Topology Not cytoplasmic

Copyright

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UniProtKB rule member sequences [?]