PRU00239
General rule information
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| Accession | PRU00239 |
| Dates | 12-DEC-2003 (Created) 21-NOV-2019 (Last updated, Version 9) |
| Data class | Domain |
| Predictors | PROSITE; PS50203; CALPAIN_CAT |
| Name | Cysteine proteinase, calpain-type, catalytic domain |
| Function | Calpains are a family of cytosolic cysteine proteinases |
Propagated annotation
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Description
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case <FTGroup:1>
| + RecName: EC 3.4.22.-; |
end case
Gene Ontology
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case <FTGroup:1>
GO:0008234; Molecular function: cysteine-type peptidase activity.
GO:0016787; Molecular function: hydrolase activity.
GO:0008233; Molecular function: peptidase activity.
GO:0016787; Molecular function: hydrolase activity.
GO:0008233; Molecular function: peptidase activity.
Keywords
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end case
Features
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| From: PS50203 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | Calpain catalytic # | |||||||||
| ACT_SITE | 61 | 61 | C | 1 | ||||||||
| ACT_SITE | 222 | 222 | H | 1 | ||||||||
| ACT_SITE | 243 | 243 | N | 1 | ||||||||
Additional information
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| Size range | 291-344 amino acids |
| Related rules | None |
| Repeats | 1 |
| Topology | Cytoplasmic |
| Example | Q9HC96 (CAN10_HUMAN) |
| Scope | Eukaryota
Bacteria |
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UniProtKB rule member sequences
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-
UniProtKB/Swiss-Prot sets
Bacteria [1] Eukaryota [77] All [ 78 ]
- Retrieve set of proteins with 3D structure for this domain