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ProRule PRU00239


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PURL: https://purl.expasy.org/prosite/rule/PRU00239
General rule information [?]

Accession PRU00239
Dates 12-DEC-2003 (Created)
21-NOV-2019 (Last updated, Version 10)
Data class Domain;
Predictors PROSITE; PS50203; CALPAIN_CAT
Name Cysteine proteinase, calpain-type, catalytic domain
Function Calpains are a family of cytosolic cysteine proteinases
Scope(s) Eukaryota
Bacteria
Example(s) Q9HC96 (CAN10_HUMAN);

Propagated annotation [?]

Identifier, protein and gene names [?]

case <FTGroup:1>
Protein name + RecName: EC=3.4.22.-;
end case

Keywords [?]

Hydrolase
Protease
Thiol protease
end case

Gene Ontology [?]

case <FTGroup:1>
GO:0008234; Molecular function:cysteine-type peptidase activity
GO:0016787; Molecular function:hydrolase activity
GO:0008233; Molecular function:peptidase activity

Features [?]

From: PS50203
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Calpain catalytic #"
ACT_SITE 61 61 C 1
ACT_SITE 222 222 H 1
ACT_SITE 243 243 N 1

Additional information [?]

Size range 291-344 amino acids
Related rules None
Fusion None
Repeats 1
Topology Cytoplasmic

Copyright

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UniProtKB rule member sequences [?]