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ProRule PRU00240


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PURL: https://purl.expasy.org/prosite/rule/PRU00240
General rule information [?]

Accession PRU00240
Dates 12-DEC-2003 (Created)
19-NOV-2022 (Last updated, Version 14)
Data class Domain;
Predictors PROSITE; PS50141; A_DEAMIN_EDITASE
Name Adenosine to inosine editase domain
Function Enzymes that catalyze the site-selective deamination of adenosine residue into inosine within double stranded regions of mRNA.
Scope(s) Eukaryota
Example(s) Q99MU3;

Propagated annotation [?]

Identifier, protein and gene names [?]

case <FTGroup:1> and <Feature:PS50141:27=E>
Protein name + RecName: EC=3.5.4.-;
end case

Keywords [?]

Hydrolase
end case
case <FTGroup:1>
Metal-binding
Zinc
end case

Gene Ontology [?]

case <FTGroup:1> and <Feature:PS50141:27=E>
GO:0016787; Molecular function:hydrolase activity

Features [?]

From: PS50141
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="A to I editase #"
BINDING 25 25 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"		 H 1
ACT_SITE 27 27 /note="Proton donor" E
BINDING 81 81 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"		 C 1
BINDING 149 149 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"		 C 1

Additional information [?]

Size range 325-367 amino acids
Related rules None
Fusion None
Repeats 1
Topology Not cytoplasmic

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]