We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU00257
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00257
General rule information
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| Accession | PRU00257 |
| Dates | 12-DEC-2003 (Created)
27-JUN-2022 (Last updated, Version 10) |
| Data class | Domain; |
| Predictors |
PROSITE; PS50943; HTH_CROC1 |
Name | Cro/C1-type HTH domain |
| Function | The cro/C1-type HTH domain is a DNA-binding, helix-turn-helix (HTH) domain in transcriptional regulators. |
| Scope(s) |
Eukaryota Bacteria Archaea Viruses |
| Example(s) | P14819; |
Propagated annotation
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Keywords
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Gene Ontology
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| GO:0003677; Molecular function:DNA binding |
| GO:0006355; Biological process:regulation of DNA-templated transcription |
| GO:0006351; Biological process:DNA-templated transcription |
Features
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| From: PS50943 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="HTH cro/C1-type #" | |||||||||
| DNA_BIND | 12 | 31 | /note="H-T-H motif" | |||||||||
Additional information
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| Size range | 53-62 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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