PRU00276

General rule information [?]

Accession	PRU00276
Dates	12-DEC-2003 (Created) 19-NOV-2022 (Last updated, Version 13)

Data class

Domain

Predictors

PROSITE; PS50215; ADAM_MEPRO

Name	ADAM type metalloprotease domain

Function

Belongs to peptidase family M12B

Propagated annotation [?]

Keywords [?]

case <FTGroup:1>

Metal-binding
Zinc

end case

case <FTTag:disulf>

Disulfide bond

end case

Features [?]

From: PS50215

Key From To Description Tag Condition FTGroup

DOMAIN from to Peptidase M12B #

BINDING 137 137 /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_note="catalytic H 1

ACT_SITE 138 138 E

BINDING 141 141 /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_note="catalytic H 1

BINDING 147 147 /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" /ligand_note="catalytic H 1

DISULFID 112 192 disulf C-x*-C

DISULFID 152 176 disulf C-x*-C

DISULFID 154 159 disulf C-x*-C

Additional information [?]

Size range	150-252 amino acids
Related rules	None
Repeats	1
Topology	Undefined
Example	P83255 (VM1F_MACLB)
Scope	Eukaryota

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

View rule in raw text format (no links)

UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets

Eukaryota [334]
Retrieve set of proteins with 3D structure for this domain