PROSITE logo

ProRule PRU00276


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00276
General rule information [?]

Accession PRU00276
Dates 12-DEC-2003 (Created)
19-NOV-2022 (Last updated, Version )
Data class Domain;
Predictors PROSITE; PS50215; ADAM_MEPRO
Name ADAM type metalloprotease domain
Function Belongs to peptidase family M12B
Scope(s) Eukaryota
Example(s) P83255;

Propagated annotation [?]

Keywords [?]

case <FTGroup:1>
Metal-binding
Zinc
end case
case <FTTag:disulf>
Disulfide bond
end case

Features [?]

From: PS50215
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Peptidase M12B #"
BINDING 137 137 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_note="catalytic"		 H 1
ACT_SITE 138 138 E
BINDING 141 141 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_note="catalytic"		 H 1
BINDING 147 147 /ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"
/ligand_note="catalytic"		 H 1
DISULFID 112 192 disulf C-x*-C
DISULFID 152 176 disulf C-x*-C
DISULFID 154 159 disulf C-x*-C

Additional information [?]

Size range 150-252 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]