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ProRule PRU00277


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PURL: https://purl.expasy.org/prosite/rule/PRU00277
General rule information [?]

Accession PRU00277
Dates 12-DEC-2003 (Created)
21-NOV-2019 (Last updated, Version 13)
Data class Domain;
Predictors PROSITE; PS50059; FKBP_PPIASE
Name PPIase FKBP-type domain
Function Peptidyl-prolyl cis-trans isomerase activity (EC 5.2.1.8)
Scope(s) Eukaryota
Bacteria
Archaea
Example(s) Q02790 (FKBP4_HUMAN);

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name + RecName: EC=5.2.1.8;

Comments [?]

CATALYTIC ACTIVITY Reaction=[protein]-peptidylproline (omega=180) = [protein]- peptidylproline (omega=0); Xref=Rhea:RHEA:16237, Rhea:RHEA- COMP:10747, Rhea:RHEA-COMP:10748, ChEBI:CHEBI:83833, ChEBI:CHEBI:83834; EC=5.2.1.8;

Keywords [?]

Isomerase
Rotamase

Gene Ontology [?]

GO:0016853; Molecular function:isomerase activity

Features [?]

From: PS50059
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="PPIase FKBP-type #"

Additional information [?]

Size range 72-130 amino acids
Related rules None
Fusion None
Repeats 1-2
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]