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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00288


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00288
General rule information [?]

Accession PRU00288
Dates 12-DEC-2003 (Created)
21-NOV-2019 (Last updated, Version 8)
Data class Domain;
Predictors PROSITE; PS50115; ARFGAP
Name ARF GTPase-activating proteins domain
Function GTPase-activating
Scope(s) Eukaryota
Example(s) Q8N6T3;

Propagated annotation [?]

Keywords [?]

Zinc-finger
case <Feature:PS50115:16=[CH]> and <Feature:PS50115:19=[CH]> and <Feature:PS50115:36=[CH]> and <Feature:PS50115:39=[CH]>
Zinc
Metal-binding
end case

Features [?]

From: PS50115
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Arf-GAP #"
case <Feature:PS50115:16=C> and <Feature:PS50115:19=C> and <Feature:PS50115:36=C> and <Feature:PS50115:39=C>
ZN_FING 16 39 /note="C4-type #"
else case <Feature:PS50115:16=[CH]> and <Feature:PS50115:19=[CH]> and <Feature:PS50115:36=[CH]> and <Feature:PS50115:39=[CH]>
ZN_FING 16 39 /note="C4-type #; atypical"
else
ZN_FING 16 39 /note="C4-type #; degenerate"
end case

Additional information [?]

Size range 110-144 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]