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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00295


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00295
General rule information [?]

Accession PRU00295
Dates 12-DEC-2003 (Created)
21-NOV-2019 (Last updated, Version 8)
Data class Domain;
Predictors PROSITE; PS50189; NTR
Name NTR domain
Function The NTR domain is implicated in inhibition of zinc metalloproteinases of the metzincin family.
Scope(s) Eukaryota
Example(s) P97299;

Propagated annotation [?]

Keywords [?]

case <FTTag:disulf>
Disulfide bond
end case

Features [?]

From: PS50189
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="NTR #"
DISULFID 1 76 disulf C-x*-C 1
case <FTGroup:1>
DISULFID 5 78 disulf C-x*-C
DISULFID 5 107 disulf C-x*-C
end case
DISULFID 19 134 disulf C-x*-C 1

Additional information [?]

Size range 110-200 amino acids
Related rules None
Fusion None
Repeats 1
Topology Not cytoplasmic

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]