We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
ProRule PRU00303
View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00303
General rule information
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| Accession | PRU00303 |
| Dates | 19-DEC-2003 (Created)
21-NOV-2019 (Last updated, Version 20) |
| Data class | Domain; |
| Predictors |
case c? <OC:Bacteria> or <OC:Archaea> or <OC:Viruses>
PROSITE; PS51257; PROKAR_LIPOPROTEIN end case
|
Name | Prokaryotic membrane lipoprotein lipid attachment site |
| Function | site of signal peptide cleavage and attachment of glyceride-fatty acid lipids that anchor proteins in the membrane |
| Scope(s) |
Bacteria Archaea Viruses |
| Example(s) | P23898; |
Propagated annotation
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Identifier, protein and gene names
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| Protein name | + Flags: Precursor; |
Comments
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| case not <Triggered> | |
| SUBCELLULAR LOCATION | Cell membrane; Lipid-anchor. |
| end case | |
Keywords
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| case not <Triggered> | |
| Membrane | |
| end case | |
| Palmitate | |
| Signal | |
| Lipoprotein | |
Gene Ontology
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| case not <Triggered> | |
| GO:0005886; Cellular component:plasma membrane | |
| end case | |
Features
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| From: PS51257 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| SIGNAL | 1 | 34 | ||||||||||
| LIPID | 35 | 35 | /note="N-palmitoyl cysteine" | |||||||||
| LIPID | 35 | 35 | /note="S-diacylglycerol cysteine" | |||||||||
| CHAIN | 35 | Cter | /note=" |
|||||||||
Additional information
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| Size range | 14-35 amino acids |
| Related rules |
ANA00006 ANA00002 |
| Fusion | None |
| Repeats | 1 |
| Topology | Not cytoplasmic |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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