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annotation rule: PRU00304

General rule information [?]

Accession PRU00304
Dates 19-DEC-2003 (Created)
9-MAY-2017 (Last updated, Version 5)
Data class Domain
Predictors PROSITE; PS50211; DENN
Name DENN domain
Function The tripartite DENN domain is composed of three distinct modules which are always associated due to functional and/or structural constraints: upstream DENN or uDENN, the better conserved central or core or cDENN, and downstream or dDENN regions. The function of DENN domain remains to date unclear, although it appears to represent a good candidate for a GTP/GDP exchange activity.

Propagated annotation [?]


Features [?]

From: PS50211
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     162       uDENN #        
DOMAIN     185     321       cDENN #        
DOMAIN     323     to       dDENN #        

Additional information [?]

Size range 180-230 amino acids
Related rules None
Repeats 1
Topology Cytoplasmic
Example O02626 (MADD_CAEEL)
Scope
Eukaryota; Metazoa

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



UniProtKB rule member sequences [?]

UniProtKB/Swiss-Prot sets
Eukaryota [68]