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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00307


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00307
General rule information [?]

Accession PRU00307
Dates 22-DEC-2003 (Created)
27-JUN-2022 (Last updated, Version 10)
Data class Domain;
Predictors PROSITE; PS50949; HTH_GNTR
Name GntR-type HTH domain
Function The gntR-type HTH domain is a DNA-binding, winged helix-turn-helix (wHTH) domain of about 60-70 residues present in transcriptional regulators of the gntR family.
Scope(s) Bacteria
Example(s) Q9S470;

Propagated annotation [?]

Keywords [?]

DNA-binding
Transcription
Transcription regulation

Gene Ontology [?]

GO:0003677; Molecular function:DNA binding
GO:0006355; Biological process:regulation of DNA-templated transcription
GO:0006351; Biological process:DNA-templated transcription

Features [?]

From: PS50949
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="HTH gntR-type #"
DNA_BIND 29 48 /note="H-T-H motif"

Additional information [?]

Size range 50-75 amino acids
Related rules None
Fusion None
Repeats 1
Topology Cytoplasmic

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]