ProRule PRU00309
General rule information
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Accession | PRU00309 |
Dates | 14-JAN-2004 (Created)
21-NOV-2019 (Last updated, Version 10) |
Data class | Domain; |
Predictors |
PROSITE; PS50950; THAP |
Name | Zinc finger THAP-type |
Function | The THAP-type zinc finger is supposed to be a DNA-binding domain. |
Scope(s) |
Eukaryota Metazoa |
Example(s) | Q9NVV9 (THAP1_HUMAN); |
Propagated annotation
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Keywords
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Zinc-finger | |
DNA-binding | |
case <Feature:PS50950:5=[CH]> and <Feature:PS50950:10=[CH]> and <Feature:PS50950:55=[CH]> and <Feature:PS50950:58=[CH]> | |
Zinc | |
Metal-binding | |
end case |
Gene Ontology
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GO:0003677; Molecular function:DNA binding | |
case <Feature:PS50950:5=[CH]> and <Feature:PS50950:10=[CH]> and <Feature:PS50950:55=[CH]> and <Feature:PS50950:58=[CH]> | |
GO:0046872; Molecular function:metal ion binding | |
GO:0008270; Molecular function:zinc ion binding | |
end case |
Features
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From: PS50950 | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
case <Feature:PS50950:5=C> and <Feature:PS50950:10=C> and <Feature:PS50950:55=C> and <Feature:PS50950:58=H> | ||||||||||||
ZN_FING | 5 | 58 | /note="THAP-type #" | |||||||||
else case <Feature:PS50950:5=[CH]> and <Feature:PS50950:10=[CH]> and <Feature:PS50950:55=[CH]> and <Feature:PS50950:58=[CH]> | ||||||||||||
ZN_FING | 5 | 58 | /note="THAP-type #; atypical" | |||||||||
else | ||||||||||||
ZN_FING | 5 | 58 | /note="THAP-type #; degenerate" | |||||||||
end case |
Additional information
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Size range | 70-100 amino acids |
Related rules |
None |
Fusion | None |
Repeats | 1-27 |
Topology | Cytoplasmic |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [47] All [ 47 ]
- Retrieve set of proteins with 3D structure for this domain