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annotation rule: PRU00309

General rule information [?]

Accession PRU00309
Dates 14-JAN-2004 (Created)
21-NOV-2019 (Last updated, Version 10)
Data class Domain
Predictors PROSITE; PS50950; THAP
Name Zinc finger THAP-type
Function The THAP-type zinc finger is supposed to be a DNA-binding domain.

Propagated annotation [?]


Gene Ontology [?]

GO:0003677; Molecular function: DNA binding.
case <Feature:PS50950:5=[CH]> and <Feature:PS50950:10=[CH]> and <Feature:PS50950:55=[CH]> and <Feature:PS50950:58=[CH]>
GO:0046872; Molecular function: metal ion binding.
GO:0008270; Molecular function: zinc ion binding.
end case


Keywords [?]

Zinc-finger
DNA-binding
case <Feature:PS50950:5=[CH]> and <Feature:PS50950:10=[CH]> and <Feature:PS50950:55=[CH]> and <Feature:PS50950:58=[CH]>
Zinc
Metal-binding
end case


Features [?]

case <Feature:PS50950:5=C> and <Feature:PS50950:10=C> and <Feature:PS50950:55=C> and <Feature:PS50950:58=H>
From: PS50950
Key     From     To       Description   Tag   Condition   FTGroup
ZN_FING     5     58       THAP-type #        
else case <Feature:PS50950:5=[CH]> and <Feature:PS50950:10=[CH]> and <Feature:PS50950:55=[CH]> and <Feature:PS50950:58=[CH]>
ZN_FING     5     58       THAP-type #; atypical        
else
ZN_FING     5     58       THAP-type #; degenerate        
end case


Additional information [?]

Size range 70-100 amino acids
Related rules None
Repeats 1-27
Topology Cytoplasmic
Example Q9NVV9 (THAP1_HUMAN)
Scope
Eukaryota; Metazoa

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.


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UniProtKB rule member sequences [?]