PROSITE logo

ProRule PRU00309


General rule information [?]

PURL https://purl.expasy.org/prosite/rule/PRU00309
Accession PRU00309
Dates 14-JAN-2004 (Created)
21-NOV-2019 (Last updated, Version 10)
Data class Domain;
Predictors PROSITE; PS50950; THAP
Name Zinc finger THAP-type
Function The THAP-type zinc finger is supposed to be a DNA-binding domain.
Scope(s) Eukaryota
Metazoa
Example(s) Q9NVV9 (THAP1_HUMAN);

Propagated annotation [?]

Keywords [?]

Zinc-finger
DNA-binding
case <Feature:PS50950:5=[CH]> and <Feature:PS50950:10=[CH]> and <Feature:PS50950:55=[CH]> and <Feature:PS50950:58=[CH]>
Zinc
Metal-binding
end case

Gene Ontology [?]

GO:0003677; Molecular function:DNA binding
case <Feature:PS50950:5=[CH]> and <Feature:PS50950:10=[CH]> and <Feature:PS50950:55=[CH]> and <Feature:PS50950:58=[CH]>
GO:0046872; Molecular function:metal ion binding
GO:0008270; Molecular function:zinc ion binding
end case

Features [?]

From: PS50950
Key From To Description Tag Condition FTGroup
case <Feature:PS50950:5=C> and <Feature:PS50950:10=C> and <Feature:PS50950:55=C> and <Feature:PS50950:58=H>
ZN_FING 5 58 /note="THAP-type #"
else case <Feature:PS50950:5=[CH]> and <Feature:PS50950:10=[CH]> and <Feature:PS50950:55=[CH]> and <Feature:PS50950:58=[CH]>
ZN_FING 5 58 /note="THAP-type #; atypical"
else
ZN_FING 5 58 /note="THAP-type #; degenerate"
end case

Additional information [?]

Size range 70-100 amino acids
Related rules None
Fusion None
Repeats 1-27
Topology Cytoplasmic

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.



View rule in raw text format (no links)

UniProtKB rule member sequences [?]