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ProRule PRU00315


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PURL: https://purl.expasy.org/prosite/rule/PRU00315
General rule information [?]

Accession PRU00315
Dates 22-JAN-2004 (Created)
21-NOV-2019 (Last updated, Version 20)
Data class Domain;
Predictors PROSITE; PS50948; PAN
Name PAN/Apple domain
Function The PAN/Apple domain has been shown to bind directly to kininogen, factor XIIa, platelets,factor IX and heparin.
Scope(s) Eukaryota
Metazoa
Example(s) P03951 (FA11_HUMAN); P14210 (HGF_HUMAN);

Propagated annotation [?]

Keywords [?]

case <FTTag:disulf>
Disulfide bond
end case

Cross-references [?]

PROSITE PS00495; APPLE; 1;

Features [?]

From: PS50948
Key From To Description Tag Condition FTGroup
case <AnyFeature:PS50948:1={C}> or <AnyFeature:PS50948:78={C}>
DOMAIN from to /note="PAN #"
else
DOMAIN from to /note="Apple #"
end case
DISULFID 1 78 disulf C-x*-C
DISULFID 30 52 disulf C-x*-C
DISULFID 34 40 disulf C-x*-C

Additional information [?]

Size range 72-95 amino acids
Related rules None
Fusion None
Repeats 4
Topology Not cytoplasmic

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]