PROSITE logo

ProRule logo
PRU00315


General rule information [?]

Accession PRU00315
Dates 22-JAN-2004 (Created)
21-NOV-2019 (Last updated, Version 19)
Data class Domain
Predictors PROSITE; PS50948; PAN
Name PAN/Apple domain
Function The PAN/Apple domain has been shown to bind directly to kininogen, factor XIIa, platelets,factor IX and heparin.

Propagated annotation [?]


Cross-references [?]

case not <AnyFeature:PS50948:1={C}> and not <AnyFeature:PS50948:78={C}>
PROSITE PS00495; APPLE; 1;
end case


Keywords [?]

case <FTTag:disulf>
Disulfide bond
end case


Features [?]

case <AnyFeature:PS50948:1={C}> or <AnyFeature:PS50948:78={C}>
From: PS50948
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       PAN #        
else
DOMAIN     from     to       Apple #        
end case

DISULFID     1     78           disulf   C-x*-C  
DISULFID     30     52           disulf   C-x*-C  
DISULFID     34     40           disulf   C-x*-C  

Additional information [?]

Size range 72-95 amino acids
Related rules None
Repeats 4
Topology Not cytoplasmic
Examples P03951 (FA11_HUMAN); P14210 (HGF_HUMAN): [Recover all]
Scope
Eukaryota; Metazoa

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.


View rule in raw text format (no links)


UniProtKB rule member sequences [?]