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annotation rule: PRU00315

General rule information [?]

Accession PRU00315
Dates 22-JAN-2004 (Created)
19-DEC-2016 (Last updated, Version 18)
Data class Domain
Predictors PROSITE; PS50948; PAN
Name PAN/Apple domain
Function The PAN/Apple domain has been shown to bind directly to kininogen, factor XIIa, platelets,factor IX and heparin.

Propagated annotation [?]


Cross-references [?]

case not <AnyFeature:PS50948:1={C}> and not <AnyFeature:PS50948:78={C}>
PROSITE PS00495; APPLE; 1;
end case


Keywords [?]

case <FTTag:disulf>
end case


Features [?]

case <AnyFeature:PS50948:1={C}> or <AnyFeature:PS50948:78={C}>
From: PS50948
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       PAN #        
else
DOMAIN     from     to       Apple #        
end case

DISULFID     1     78           disulf   C-x*-C  
DISULFID     30     52           disulf   C-x*-C  
DISULFID     34     40           disulf   C-x*-C  

Additional information [?]

Size range 72-95 amino acids
Related rules None
Repeats 4
Topology Not cytoplasmic
Examples P03951 (FA11_HUMAN); P14210 (HGF_HUMAN): [Recover all]
Scope
Eukaryota; Metazoa

Copyright

PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to license@isb-sib.ch or see: prosite_license.html.



UniProtKB rule member sequences [?]