ProRule PRU00318
General rule information
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| PURL | https://purl.expasy.org/prosite/rule/PRU00318 |
| Accession | PRU00318 |
| Dates | 22-JAN-2004 (Created)
21-NOV-2019 (Last updated, Version 6) |
| Data class | Domain; |
| Predictors |
PROSITE; PS50303; PUM_HD |
Name | Pumilio homology domain |
| Function | Pumilio homology domain has been shown to bind specific RNA sequences mainly found in the 3' UTR of mRNA and repress their translation. |
| Scope(s) |
Eukaryota |
| Example(s) | P25822 (PUM_DROME); |
Propagated annotation
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Features
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| From: PS50303 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="PUM-HD #" | |||||||||
Additional information
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| Size range | 300-450 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Not cytoplasmic |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [64] All [ 64 ]
- Retrieve set of proteins with 3D structure for this domain