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annotation rule: PRU00331

General rule information [?]

Accession PRU00331
Dates 29-MAR-2004 (Created)
16-DEC-2016 (Last updated, Version 5)
Data class Domain
Predictors PROSITE; PS50957; JOSEPHIN
Name Josephin domain
Function The Josephin domain is believed to be a mainly alpha helical cysteine-protease domain predicted to be active against ubiquitin chains or related substrates.

Propagated annotation [?]


Gene Ontology [?]

case <FTGroup:1>
GO:0016787; Molecular function: hydrolase activity.

Keywords [?]

end case


Features [?]

From: PS50957
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       Josephin #        
ACT_SITE     14     14             C   1
ACT_SITE     117     117             H   1
ACT_SITE     132     132             [DN]   1

Additional information [?]

Size range 165-195 amino acids
Related rules None
Repeats 1
Topology Undefined
Example Q15040 (JOS1_HUMAN)
Scope
Eukaryota

Copyright

PROSITE is copyright. It is produced by the SIB Swiss Institute Bioinformatics. There are no restrictions on its use by non-profit institutions as long as its content is in no way modified. Usage by and for commercial entities requires a license agreement. For information about the licensing scheme send an email to license@isb-sib.ch or see: prosite_license.html.



UniProtKB rule member sequences [?]