ProRule PRU00331

General rule information [?]

Accession PRU00331
Dates 29-MAR-2004 (Created)
21-NOV-2019 (Last updated, Version 6)
Data class Domain;
Predictors PROSITE; PS50957; JOSEPHIN
Name Josephin domain
Function The Josephin domain is believed to be a mainly alpha helical cysteine-protease domain predicted to be active against ubiquitin chains or related substrates.
Scope(s) Eukaryota
Example(s) Q15040 (JOS1_HUMAN);

Propagated annotation [?]

Keywords [?]

case <FTGroup:1>
end case

Gene Ontology [?]

case <FTGroup:1>
GO:0016787; Molecular function:hydrolase activity
end case

Features [?]

From: PS50957
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="Josephin #"
ACT_SITE 14 14 C 1
ACT_SITE 117 117 H 1
ACT_SITE 132 132 [DN] 1

Additional information [?]

Size range 165-195 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

View rule in raw text format (no links)

UniProtKB rule member sequences [?]