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| annotation rule: PRU00331 |
General rule information
[?]
| Accession | PRU00331 |
| Dates | 29-MAR-2004 (Created) 21-NOV-2019 (Last updated, Version 6) |
| Data class | Domain |
| Predictors | PROSITE; PS50957; JOSEPHIN |
| Name | Josephin domain |
| Function | The Josephin domain is believed to be a mainly alpha helical cysteine-protease domain predicted to be active against ubiquitin chains or related substrates. |
Propagated annotation
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Gene Ontology
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case <FTGroup:1>
GO:0016787; Molecular function: hydrolase activity.
Keywords
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end case
Features
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| From: PS50957 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | Josephin # | |||||||||
| ACT_SITE | 14 | 14 | C | 1 | ||||||||
| ACT_SITE | 117 | 117 | H | 1 | ||||||||
| ACT_SITE | 132 | 132 | [DN] | 1 | ||||||||
Additional information
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| Size range | 165-195 amino acids |
| Related rules | None |
| Repeats | 1 |
| Topology | Undefined |
| Example | Q15040 (JOS1_HUMAN) |
| Scope | Eukaryota |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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-
UniProtKB/Swiss-Prot sets
Eukaryota [18]
- Retrieve set of proteins with 3D structure for this domain