ProRule PRU00331
General rule information
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| Accession | PRU00331 |
| Dates | 29-MAR-2004 (Created)
21-NOV-2019 (Last updated, Version 6) |
| Data class | Domain; |
| Predictors |
PROSITE; PS50957; JOSEPHIN |
Name | Josephin domain |
| Function | The Josephin domain is believed to be a mainly alpha helical cysteine-protease domain predicted to be active against ubiquitin chains or related substrates. |
| Scope(s) |
Eukaryota |
| Example(s) | Q15040 (JOS1_HUMAN); |
Propagated annotation
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Keywords
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| case <FTGroup:1> | |
| Hydrolase | |
| end case | |
Gene Ontology
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| case <FTGroup:1> | |
| GO:0016787; Molecular function:hydrolase activity | |
| end case | |
Features
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| From: PS50957 | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | from | to | /note="Josephin #" | |||||||||
| ACT_SITE | 14 | 14 | C | 1 | ||||||||
| ACT_SITE | 117 | 117 | H | 1 | ||||||||
| ACT_SITE | 132 | 132 | [DN] | 1 | ||||||||
Additional information
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| Size range | 165-195 amino acids |
| Related rules |
None |
| Fusion | None |
| Repeats | 1 |
| Topology | Undefined |
PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.
UniProtKB rule member sequences
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- UniProtKB/Swiss-Prot sets
Eukaryota [18] All [ 18 ]
- Retrieve set of proteins with 3D structure for this domain