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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00353


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00353
General rule information [?]

Accession PRU00353
Dates 17-AUG-2004 (Created)
27-JUN-2022 (Last updated, Version 12)
Data class Domain;
Predictors PROSITE; PS51005; NAC
Name NAC domain
Function The NAC domain has been shown to be a DNA-binding domain (DBD) and a dimerization domain.
Scope(s) Eukaryota
Viridiplantae
Example(s) Q9ZNU2;

Propagated annotation [?]

Comments [?]

SUBCELLULAR LOCATIONNucleus.
DOMAINThe NAC domain includes a DNA binding domain and a dimerization domain.

Keywords [?]

DNA-binding
Nucleus
Transcription
Transcription regulation

Gene Ontology [?]

GO:0003677; Molecular function:DNA binding
GO:0005634; Cellular component:nucleus
GO:0006355; Biological process:regulation of DNA-templated transcription
GO:0006351; Biological process:DNA-templated transcription

Features [?]

From: PS51005
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="NAC #"
DNA_BIND 102 to+6

Additional information [?]

Size range 145-175 amino acids
Related rules None
Fusion None
Repeats 1-2
Topology Not cytoplasmic

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]