PROSITE logo
Black ribbon
We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00361


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00361
General rule information [?]

Accession PRU00361
Dates 11-OCT-2004 (Created)
21-NOV-2019 (Last updated, Version 7)
Data class Domain;
Predictors PROSITE; PS51021; BAR
Name BAR domain
Function BAR domain containing proteins are a unique class of adaptor proteins characterized by a common N-terminal fold termed the BAR domain.
Scope(s) Eukaryota
Bacteria
Archaea
Example(s) P49418;

Propagated annotation [?]

Keywords [?]

Coiled coil

Features [?]

From: PS51021
Key From To Description Tag Condition FTGroup
DOMAIN from to /note="BAR"

Additional information [?]

Size range 222 amino acids
Related rules None
Fusion None
Repeats 1
Topology Undefined
Comments Recent papers, based on sequence and structural similarities have shown that a conserved region in more divergent families, like oligophrenin, centaurin beta, sorting nexin, ICA69, pick1 or arfaptins, is related to the BAR domain. These families are however too divergent to be detected by the profile.

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]