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annotation rule: PRU00361

General rule information [?]

Accession PRU00361
Dates 11-OCT-2004 (Created)
21-NOV-2019 (Last updated, Version 6)
Data class Domain
Predictors PROSITE; PS51021; BAR
Name BAR domain
Function BAR domain containing proteins are a unique class of adaptor proteins characterized by a common N-terminal fold termed the BAR domain.

Propagated annotation [?]

Keywords [?]

Features [?]

From: PS51021
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     from     to       BAR        

Additional information [?]

Size range 222 amino acids
Related rules None
Repeats 1
Topology Undefined
Example P49418 (AMPH_HUMAN)
Comments Recent papers, based on sequence and structural similarities have shown that a conserved region in more divergent families, like oligophrenin, centaurin beta, sorting nexin, ICA69, pick1 or arfaptins, is related to the BAR domain. These families are however too divergent to be detected by the profile.


PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]