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We are deeply saddened by the passing of Amos Bairoch (1957–2025), the creator of PROSITE. We wish to dedicate our latest paper, published shortly before his death, to him. He will always be a source of inspiration to us.
Our deepest condolences go out to his family and friends, and to all those who had the privilege of working with him. Rest in peace, Amos. Your work will live on long after you are gone.
Amos Bairoch

ProRule PRU00373


View rule in raw text format (no links)
PURL: https://purl.expasy.org/prosite/rule/PRU00373
General rule information [?]

Accession PRU00373
Dates 23-NOV-2004 (Created)
21-NOV-2019 (Last updated, Version 4)
Data class Domain;
Predictors PROSITE; PS50909; GAT
Name GAT domain
Function The GAT domain of GGAs serves as a molecular anchor of GGA to trans- Golgi network (TGN) membranes via its interaction with the GTP-bound form of a member of the ARF family of small GTPases and can bind specifically to the Rab GTPase effector rabaptin5 and to ubiquitin.
Scope(s) Eukaryota
Example(s) Q9UJY5; O60784;

Propagated annotation [?]

Keywords [?]

Membrane
Protein transport
Transport

Gene Ontology [?]

GO:0016020; Cellular component:membrane
GO:0015031; Biological process:protein transport
GO:0006810; Biological process:transport

Features [?]

From: PS50909
Key From To Description Tag Condition FTGroup
DOMAIN entry exit /note="GAT #"

Additional information [?]

Size range 85-130 amino acids
Related rules None
Fusion None
Repeats 1
Topology Cytoplasmic

Copyright

PROSITE is copyrighted by the SIB Swiss Institute of Bioinformatics and distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND 4.0) License, see prosite_license.html.

UniProtKB rule member sequences [?]